Cornea and its changes in diabetes mellitus: the review
https://doi.org/10.14341/DM7972
Abstract
About the Authors
Mukharram M. BikbovRussian Federation
MD, PhD, Director
Competing Interests: Конфтикт интересов отсутствует
Valentina K. Surkova
Russian Federation
MD, PhD, Professor, leading research associate
Competing Interests: No conflict of interests
References
1. Дедов И.И., Шестакова М.В., Галстян Г.Р. Распространенность сахарного диабета 2 типа у взрослого населения России (исследование NATION) // Сахарный диабет. – 2016. – Т. 19. – №2 – C. 104-112. [Dedov II, Shestakova MV, Galstyan GR. The prevalence of type 2 diabetes mellitus in the adult population of Russia (NATION study). Diabetes mellitus. 2016;19(2):104-112. (In Russ).] doi: 10.14341/DM2004116-17
2. Дедов И.И., Омельяновский В.В., Шестакова М.В., и др. Cахарный диабет как экономическая проблема в Российской Федерации // Сахарный диабет. – 2016. – Т. 19. – №1 – C. 30-43. [Dedov II, Omelyanovskiy VV, Shestakova MV, Avksentieva MV, Ignatieva VI. Diabetes mellitus as an economic problem in Russian Federation. Diabetes mellitus. 2016;19(1):30-43. (In Russ).]. doi: 10. 14341/DM 7784
3. Сахарный диабет и нарушения углеводного обмена. Эндокринология по Вильямсу / Под ред. Дедова И.И., Мельниченко Г.А. – Рид Элсивер; 2010. [Diabetes mellitus and disorders of carbohydrate metabolism. Endocrinology for Williams / Ed by Dedov II, Mel’nichenko GA. Rid Elsiver; 2010. (In Russ).]
4. Балашевич Л.И., Бржевский В.В., Измайлов А.С., и др. Глазные проявления диабета. – М.: Медицина; 2004. [Balashevich LI, Brzhevskii VV, Izmailov AS, et al. Glaznye proyavleniya diabeta. Moscow: Medicina; 2004. (In Russ).]
5. Lockwood A, Hope-Ross M, Chell P. Neurotrophic keratopathy and diabetes mellitus. Eye (Lond). 2006;20(7):837-839. doi: 10.1038/sj.eye.6702053
6. Sweeney DF, Millar TJ, Raju SR. Tear film stability: a review. Exp Eye Res. 2013;117:28-38. doi: 10.1016/j.exer.2013.08.010
7. Сафонова Т.Н., Патеюк А.С. Система глазной поверхности. // Вестник офтальмологии. 2015. – Т. 131. – №1. – С.96 – 102. [Safonova TN, Pateyuk LS. Ocular surface system integrity. Vestnik oftal’mologii. 2015;131(1):96-102. (In Russ)]. doi: 10.17116/oftalma2015131196-102
8. Marfurt CF, Cox J, Deek S, Dvorscak L. Anatomy of the human corneal innervation. Exp Eye Res. 2010;90(4):478-492. doi: 10.1016/j.exer.2009.12.010
9. Вит В.В. Строение зрительной системы человека. – Одесса: Астропринт; 2010. [Vit VV. The structure of the human visual system. Odessa: Astroprint; 2010. (In Russ).]
10. Krachmer J., Mannis M., Holland E. Eds. Cornea fundamentals, diagnosis, and management. 3 rd ed. Mosby Elsevier. St. Louis; 2011.
11. Al-Aqaba MA, Fares U, Suleman H, et al. Architecture and distribution of human corneal nerves. Br J Ophthalmol. 2010;94(6):784-789. doi: 10.1136/bjo.2009.173799
12. He J, Bazan NG, Bazan HE. Mapping the entire human corneal nerve architecture. Exp Eye Res. 2010;91(4):513-523. doi: 10.1016/j.exer.2010.07.007
13. DeMill DL, Hussain M, Pop-Busui R, Shtein RM. Ocular surface disease in patients with diabetic peripheral neuropathy. Br J Ophthalmol. 2015. pii: bjophthalmol-2015-307369. doi: 10.1136/bjophthalmol-2015-307369
14. Edwards K, Pritchard N, Gosschalk K, et al. Wide-Field Assessment of the Human Corneal Subbasal Nerve Plexus in Diabetic Neuropathy Using a Novel Mapping Technique. Cornea. 2012;31(9):1078-1082. doi: 10.1097/ICO.0b013e318245c012
15. Nitoda E, Kallinikos P, Pallikaris A, et al. Correlation of diabetic retinopathy and corneal neuropathy using confocal microscopy. Curr Eye Res. 2012;37(10):898-906. doi: 10.3109/02713683.2012.683507
16. Tavakoli M, Ferdousi M, Petropoulos IN, et al. Normative values for corneal nerve morphology assessed using corneal confocal microscopy: a multinational normative data set. Diabetes Care. 2015;38(5):838-843. doi: 10.2337/dc14-2311
17. Малюгин Б.Э., Марцинкевич А.О. Современные подходы к профилактике послеоперационных воспалительных осложнений в хирургии катаракты у больных с сахарным диабетом. // Офтальмохирургия. – 2016. – Т. 1. – С.85-90. [Malyugin BE, Martsinkevich AO. Modern approaches to the prevention of post-cataract surgery inflammation in diabetic patients. Oftal’mohirurgija. 2016;1:85-90. (In Russ)].
18. Lauria G, Hsieh ST, Johansson O, et al. European Federation of Neurological Societies/Peripheral Nerve Society Guideline on the use of skin biopsy in the diagnosis of small fiber neuropathy. Report of a joint task force of the European Federation of Neurological Societies and the Peripheral Nerve Society. Eur J Neurol. 2010;17(7):903-912, e944-909. doi: 10.1111/j.1468-1331.2010.03023.x
19. Tesfaye S, Boulton AJ, Dyck PJ, et al. Diabetic neuropathies: update on definitions, diagnostic criteria, estimation of severity, and treatments. Diabetes Care. 2010;33(10):2285-2293. doi: 10.2337/dc10-1303
20. Аветисов С.Э., Егорова Г.Б., Кобзева М.В., и др. Клиническое значение современных методов исследования роговицы. // Вестник офтальмологии. – 2013 – №5. – С.22-31. [Avetisov SE, Egorova GB, Kobzeva MV, et al. The clinical significance of contemporary research methods cornea. Vestnik oftal’mologii. 2013;(5):22-31. (In Russ)]
21. Tavakoli M, Hossain P, Malik RA. Clinical applications of corneal confocal microscopy. Clinical ophthalmology (Auckland, N.Z.). 2008;2(2):435-445.
22. Petropoulos IN, Manzoor T, Morgan P, et al. Repeatability of In Vivo Corneal Confocal Microscopy to Quantify Corneal Nerve Morphology. Cornea. 2013;32(5):e83-e89. doi: 10.1097/ICO.0b013e3182749419
23. Dabbah MA, Graham J, Petropoulos IN, et al. Automatic analysis of diabetic peripheral neuropathy using multi-scale quantitative morphology of nerve fibres in corneal confocal microscopy imaging. Med Image Anal. 2011;15(5):738-747. doi: 10.1016/j.media.2011.05.016
24. Егорова Г.Б., Рогова А.Я., Митичкина Т.С. Диагностические возможности конфокальной микроскопии первичных эктазий роговицы. // Вестник офтальмологии. – 2012 – №6 – С.25-29. [Egorova GB, Rogova AYa, Mitichkina TS. The diagnostic capabilities of confocal microscopy of primary corneal ectasia. Vestnik oftal’mologii. 2012;(6):25-29. (In Russ)].
25. Malik RA, Kallinikos P, Abbott CA, et al. Corneal confocal microscopy: a non-invasive surrogate of nerve fibre damage and repair in diabetic patients. Diabetologia. 2003;46(5):683-688. doi: 10.1007/s00125-003-1086-8
26. Quattrini C, Tavakoli M, Jeziorska M, et al. Surrogate markers of small fiber damage in human diabetic neuropathy. Diabetes. 2007;56(8):2148-2154. doi: 10.2337/db07-0285
27. Артемова Е.В., Галстян Г.Р., Атарщиков Д.С., и др. Конфокальная микроскопия роговицы – новый неинвазивный метод диагностики начальных проявлений повреждения периферической нервной системы при сахарном диабете. // Проблемы эндокринологии. – 2015 – Т. 61. – №2 – С.32-38. [Artemova EV, Galstyan GR, Atarshchikov DS, et al. Confocal retinal microscopy – the new non-invasive method for diagnostics of the early manifestations of the lesions in the peripheral nervous system associated with diabetes mellitus. Problems of Endocrinology. 2015;61(2):32-38. (In Russ)] doi: 10.14341/probl201561232-38.
28. Huang D, Li Y, Radhakrishnan S. Optical coherence tomography of the anterior segment of the eye. Ophthalmology Clinics of North America. 2004;17(1):1-6. doi: 10.1016/s0896-1549(03)00103-2
29. Тахчиди Х.П., Егорова Э.В., Узунян Д.Г. Ультразвуковая биомикроскопия в диагностике патологии переднего сегмента глаза. – М.: Издательский центр «Микрохирургия глаза»; 2007. [Takhchidi KhP, Egorova EV, Uzunyan DG. Ultrasound biomicroscopy in the diagnosis of diseases of anterior segment of the eye. Moscow: Izdatel’skii tsentr «Mikrokhirurgiya glaza»; 2007. (In Russ)].
30. Bikbova G, Oshitari T, Tawada A, Yamamoto S. Corneal Changes in Diabetes Mellitus. Current Diabetes Reviews. 2012;8(4):294-302. doi: 10.2174/157339912800840479
31. Inoue K, Kato S, Ohara C, et al. Ocular and Systemic Factors Relevant to Diabetic Keratoepitheliopathy. Cornea. 2001;20(8):798-801. doi: 10.1097/00003226-200111000-00004
32. Nakahara M, Miyata K, Otani S, et al. A randomised, placebo controlled clinical trial of the aldose reductase inhibitor CT-112 as management of corneal epithelial disorders in diabetic patients. Br J Ophthalmol. 2005;89(3):266-268. doi: 10.1136/bjo.2004.049841
33. Бржеский В.В. Синдром «сухого глаза». Офтальмология. Национальное руководство / Под редакцией С.Э. Аветисова, Е.А. Егорова, Л.К. Мошетовой, В.В. Нероева, Х.П. Тахчиди. М.: ГЭОТАР-Медиа; 2008. [Brzheskii VV. The syndrome of «dry eye». Ophthalmology. National leadership / Edited by SE Avetisov, EA Egorov, LK Mosheta, VV Neroev, KhP Takhchidi. Moscow: GEOTAR-Media; 2008. (In Russ).]
34. Petropoulos IN, Manzoor T, Morgan P, et al. Repeatability of in vivo corneal confocal microscopy to quantify corneal nerve morphology. Cornea. 2013;32(5):e83-89. doi: 10.1097/ICO.0b013e3182749419
35. Dehghani C, Pritchard N, Edwards K, et al. Fully automated, semiautomated, and manual morphometric analysis of corneal subbasal nerve plexus in individuals with and without diabetes. Cornea. 2014;33(7):696-702. doi: 10.1097/ICO.0000000000000152
36. Сурнина З.В. Возможности световой и лазерной биомикроскопии роговицы в ранней диагностике диабетической полинейропатии. // Вестник офтальмологии. – 2015. – Т. 131. – №1 – С.104-108. [Surnina ZV. Opportunities for confocal and laser biomicroscopy of corneal nerves in diabetic polyneuropathy. Vestnik oftal’mologii. 2015;131(1):104-108. (In Russ).] doi: 10.17116/oftalma20151311104-108
37. Аветисов С.Э., Новиков И.А., Махотин С.С., Сурнина З.В. Новый принцип морфометрического исследования нервных волокон роговицы на основе конфокальной биомикроскопии при сахарном диабете. // Вестник офтальмологии. – 2015 – №4. – С.5-14. [Avetisov SE, Novikov IA, Makhotin SS, Surnina ZV. New approach to corneal nerve fibers morphometry in diabetes mellitus on the basis of confocal biomicroscopy. Vestnik oftal’mologii. 2015;131(4):5-14. (In Russ)] doi: 10.17116/oftalma201513145-14
38. Edwards K, Pritchard N, Vagenas D, et al. Standardizing corneal nerve fibre length for nerve tortuosity increases its association with measures of diabetic neuropathy. Diabet Med. 2014;31(10):1205-1209. doi: 10.1111/dme.12466
39. Quadrado MJ, Popper M, Morgado AM, et al. Diabetes and corneal cell densities in humans by in vivo confocal microscopy. Cornea. 2006;25(7):761-768. doi: 10.1097/01.ico.0000224635.49439.d1
40. Efron N, Lee G, Lim RN, et al. Development and validation of the QUT corneal nerve grading scale. Cornea. 2014;33(4):376-381. doi: 10.1097/ICO.0000000000000084
41. Leelawongtawun W, Suphachearaphan W, Kampitak K, Leelawongtawun R. A comparative study of corneal endothelial structure between diabetes and non-diabetes. J Med Assos Thai. 2015;98(5):484-488.
42. Shenoy R, Khandekar R, Bialasiewicz A, Al Muniri A. Corneal endothelium in patients with diabetes mellitus: a historical cohort study. Eur J Ophthalmol. 2009;19(3):369. doi: 10.5301/EJO.2009.4277
43. Larsson L-I. Structure and Function of the Corneal Endothelium in Diabetes Mellitus Type I and Type II. Archives of Ophthalmology. 1996;114(1):9. doi: 10.1001/archopht.1996.01100130007001
44. Wollensak G, Wilsch M, Spoerl E, Seiler T. Collagen Fiber Diameter in the Rabbit Cornea After Collagen Crosslinking by Riboflavin/UVA. Cornea. 2004;23(5):503-507. doi: 10.1097/01.ico.0000105827.85025.7f
45. Бикбов М.М., Суркова В.К., Зайнуллина Н.Б., и др. Морфологические изменения роговицы после лечения кератоконуса методом кросслинкинга роговичного коллагена. // Катарактальная и рефракционная хирургия. – 2014. – Т. 14. – №3 – С.18-22. [Bikbov M, Bikbova G, Surkova V, et al. Morphological changes in cornea after corneal collagen cross-linking as keratoconus treatment. Cataractal and Refractive Surgery. 2014;14(3):18-22. (In Russ)]
46. Бикбов М.М., Бикбова Г.М. Эктазия роговицы. – М.: Офтальмология; 2011. [Bikbov MM, Bikbova GM. Corneal ectasia. Moscow: Oftal’mologija; 2011. (In Russ)].
47. Naderan M, Naderan M, Rezagholizadeh F, et al. Association between diabetes and keratoconus: a case-control study. Cornea. 2014;33(12):1271-1273. doi: 10.1097/ICO.0000000000000282
48. Seiler T, Huhle S, Spoerl E, Kunath H. Manifest diabetes and keratoconus: A retrospective case-control study. Graefe’s Archive for Clinical and Experimental Ophthalmology. 2000;238(10):822-825. doi: 10.1007/s004179900111
49. Kuo IC, Broman A, Pirouzmanesh A, Melia M. Is there an association between diabetes and keratoconus? Ophthalmology. 2006;113(2):184-190. doi: 10.1016/j.ophtha.2005.10.009
50. Halkiadakis I, Belfair N, Gimbel HV. Laser in situ keratomileusis in patients with diabetes. J Cataract Refract Surg. 2005;31(10):1895-1898. doi: 10.1016/j.jcrs.2005.03.075
51. Simpson RG, Moshirfar M, Edmonds JN, Christiansen SM. Laser in-situ keratomileusis in patients with diabetes mellitus: a review of the literature. Clin Ophthalmol. 2012;6:1665-1674. doi: 10.2147/OPTH.S36382
52. Балашевич Л.И., Измайлов А.С. Диабетическая офтальмопатия. – СПб.: Изд. «Человек»; 2012. [Balashevich LI, Izmailov AS. Diabetic ophthalmopathy. Saint-Petersburg.: Izd. «Chelovek»; 2012. (In Russ).]
53. Pinarci EY, Bayar SA, Sizmaz S, et al. Anterior segment complications after phacovitrectomy in diabetic and nondiabetic patients. Eur J Ophthalmol. 2013;23(2):223-229. doi: 10.5301/ejo.5000203
54. Chen H-F, Yeung L, Yang K-J, Sun C-C. Persistent corneal epithelial defect after pars plana vitrectomy. Retina. 2016;36(1):148-155.
Supplementary files
Review
For citations:
Bikbov M.M., Surkova V.K. Cornea and its changes in diabetes mellitus: the review. Diabetes mellitus. 2016;19(6):479-485. (In Russ.) https://doi.org/10.14341/DM7972

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