A comparison of the clinical outcomes of induced and spontaneous labour in patients with gestational diabetes
https://doi.org/10.14341/DM2004130-33
Abstract
Aim. To evaluate the clinical outcomes of induced and spontaneous labour in patients with gestational diabetes (GD).
Materials and methods. This retrospective cohort study conducted at the Federal Almazov Northwest Medical Research Centre included 251 patients with GD who had given birth during 2014. The patients were divided into the following two groups: one included 210 patients who were treated with diet and the other included 41 patients who were treated with insulin. Clinical outcomes were compared between patients who had induced (n = 43) or spontaneous (n = 188) labour.
Results. Complications of labour, such as dysthyroidism and uterine inertia, were significantly more common (p < 0. 05) in induced labour patients than in those who had spontaneous labour (16. 3 vs. 3. 2% and 7% vs. 0%, respectively). Fetal distress occurred in 10. 6% and 9. 3% of patients during spontaneous and induced labour, respectively. The frequency of ceasarean section after induced labour was not significantly greater than that among patients who had spontaneous labour.
Conclusion. Delivery at 38 to 39 weeks in women with GD has led to an increase in the rate of birth complications, such as uterine inertia and dysthyroidism. Gestational age cannot be considered as a sufficient indicator of labour induction at full-term in the absence of foetus distress or poor maternal glycemic control.
About the Authors
Ofelia A. BettikherRussian Federation
MD, Clinical resident at Obstetrics and Gynaecology Department
Irina E. Zazerskaya
Russian Federation
MD, PhD (Institute of Perinatology and Pediatrics, Research Laboratory of Women’s Health and Reproduction), Head of Obstetrics and Gynaecology Department
Polina V. Popova
Russian Federation
MD, PhD, Head of the Scientific Laboratory of Endocrine Diseases in Pregnant at Federal Almazov North-West Medical Research Centre
Vitaliy N. Kustarov
Russian Federation
MD, PhD, Professor at Obstetrics and Gynaecology Department of Federal Almazov North-West Medical Research Centre
References
1. Бурумкулова Ф.Ф. Гестационный сахарный диабет (эндокринологические, акушерские и перинатальные аспекты): Автореф. дисс. … докт. мед. наук. – Москва; 2011. [Burumkulova FF. Gestatsionnyi sakharnyi diabet (endokrinologicheskie, akusherskie i perinatal’nye aspekty). [dissertation] Moscow; 2011. (In Russ).]
2. Kong JM, Lim K, Thompson DM. Evaluation of the International Association of the Diabetes In Pregnancy Study Group new criteria: gestational diabetes project. Can J Diabetes. 2015;39(2):128-132. doi: 10.1016/j.jcjd.2014.09.007
3. Дедов И.И., Краснопольский В.И., Сухих Г.Т. Российский национальный консенсус – гестационный сахарный диабет: диагностика, лечение, послеродовое наблюдение? // Сахарный диабет. – 2012. – Т. 15. – №4 – C. 4-10. [Dedov II, Krasnopolskiy VI, Sukhikh GT. Russian National Consensus Statement on gestational diabetes: diagnostics, treatment and postnatal care. Diabetes mellitus. 2012;15(4):4-10. (In Russ).] doi: 10.14341/2072-0351-5531
4. Sela HY, Raz I, Elchalal U. Managing labor and delivery of the diabetic mother. Expert Review of Obstetrics & Gynecology. 2014;4(5):547-554. doi: 10.1586/eog.09.44
5. Ордынский В.Ф., Макаров О.В. Сахарный диабет и беременность. Пренатальная ультразвуковая диагностика. Руководство для врачей. – М.: Издательский дом Видар-М; 2010. – с.77-82. [ Ordynskii VF, Makarov OV. Diabetes mellitus and pregnancy. Prenatal ultrasound diagnosis. A guide for physicians. Moscow: Vidar-M; 2010. p.77-82. (In Russ)]
6. Бенсон К.Б., Блют Э.И. Ультразвуковая диагностика. Практическое решение клинических проблем. Т. 3. УЗИ в акушерстве. – М.: Медицинская литература; 2014. [Benson C, Bluth E. A practical solution to clinical problems. Vol. 3. Ultrasound in obstetrics. – Moscow: Medical literature; 2014. (In Russ)]
7. Капустин Р.В., Аржанова О.Н., Беспалова О.Н., и др. Современные представления о тактике родоразрешения беременных с гестационным сахарным диабетом // Журнал акушерства и женских болезней. – 2014. – Т. LXIII. – 4. – С.4-16. [Kapustin RV, Arzhanova ON, Bespalova ON, et al. Modern concepts of tactics delivery of pregnant women with gestational diabetes mellitus. Zhurnal akusherstva i zhenskikh bolezni︠e︡ĭ. – 2014;LXIII(4):4-16. (In Russ)].
8. ACOG Practice Bulletin No. 107: Induction of labor. Obstet Gynecol. 2009;114(2 Pt 1):386-397. doi: 10.1097/AOG.0b013e3181b48ef5
9. Vendittelli F, Riviere O, Neveu B, et al. Does induction of labor for constitutionally large-for-gestational-age fetuses identified in utero reduce maternal morbidity? BMC Pregnancy Childbirth. 2014;14:156. doi: 10.1186/1471-2393-14-156
10. Sacks DA, Sacks A. Induction of labor versus conservative management of pregnant diabetic women. J Matern Fetal Neonatal Med. 2002;12(6):438-441. doi: 10.1080/jmf.12.6.438.441
11. Boulvain M, Stan C, Irion O. Elective delivery in diabetic pregnant women. Cochrane Database Syst Rev. 2001(2):CD001997. doi: 10.1002/14651858.CD001997
12. Chatfield J. Practice Guidelines. ACOG Issues Guidelines on Fetal Macrosomia. Am Fam Physician. 2001 Jul 1;64(1):169-170. Available from: http://www.aafp.org/afp/2001/0701/p169.html
13. Jacquemyn Y, Michiels I, Martens G. Elective induction of labour increases caesarean section rate in low risk multiparous women. J Obstet Gynaecol. 2012;32(3):257-259. doi: 10.3109/01443615.2011.645091
14. Bas-Lando M, Srebnik N, Farkash R, et al. Elective induction of labor in women with gestational diabetes mellitus: an intervention that modifies the risk of cesarean section. Arch Gynecol Obstet. 2014;290(5):905-912. doi: 10.1007/s00404-014-3313-6
15. McGeown P. Practice recommendations for the induction of labour. BJM. 2001;9(1):13-15. doi: 10.12968/bjom.2001.9.1.8025
16. Metzger BE, Buchanan TA, Coustan DR, et al. Summary and recommendations of the Fifth International Workshop-Conference on Gestational Diabetes Mellitus. Diabetes Care. 2007;30 Suppl 2:S251-260. doi: 10.2337/dc07-s225
17. Красный А.М., Дегтярева Е.И., и др. Гестационный сахарный диабет: перинатальное программирование – поиск новых предикторов. / VII региональный научный форум «Мать и Дитя»; 2010; Москва. [Krasnyi AM, Degtyareva EI, et al. Gestational diabetes mellitus: perinatal programming – the search for new predictors. / In the VII regional scientific forum «Mother and Child»; 2010; Moscow. (inRuss)]. Доступно по: http://www.mediexpo.ru/fileadmin/user_upload/content/pdf/thesis/tez_mdr14. pdf.
18. Шестакова Т.П. Новые подходы к диагностике и лечению сахарного диабета у беременных. / Научно-практическая конференция «Высокие технологии в лечении и профилактике сахарного диабета»; 2014; Москва. [Shestakova TP. Novye podkhody k diagnostike i lecheniyu sakharnogo diabeta u beremennykh. / Nauchno-prakticheskaya konferentsiya «Vysokie tekhnologii v lechenii i profilaktike sakharnogo diabeta»; 2014; Moscow. (inRuss)]. Доступно по: www.diabet.ru/news/?ELEMENT_ID=591
Supplementary files
Review
For citations:
Bettikher O.A., Zazerskaya I.E., Popova P.V., Kustarov V.N. A comparison of the clinical outcomes of induced and spontaneous labour in patients with gestational diabetes. Diabetes mellitus. 2016;19(2):158-163. https://doi.org/10.14341/DM2004130-33

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (CC BY-NC-ND 4.0).