A mathematical model for stratification of LADA risk groups
https://doi.org/10.14341/DM2014115-20
Abstract
Aim.
To stratify risk groups via discriminant analysis based on the most clinically relevant indications of LADA onset derived from medical history.
Materials and Methods.
Present study included 141 patients with diabetes mellitus (DM) of whom 65 had preliminary diagnosis of LADA, 40 patients were diagnosed with type 1 diabetes mellitus (T1DM) and 36 ? with type 2 diabetes mellitus (T2DM). Discriminant analysis was performed to evaluate the differences between the clinical onsets in study groups.
Results.
Aside from torpid onset with early evidence for insulin resistance, clinical characteristics of LADA included diagnosis during random examination, progressive loss of body mass, hyperglycemia greater than 14 mmol/L at the diagnosis and, possibly, ketonuria without history of acute ketoacidosis.
Conclusion.
Discriminant analysis is beneficial in stratifying risk groups for the development of LADA.
About the Author
Tatiana M. Tikhonova
V. Danilevsky Institute for Endocrine Pathology Problems, Kharkiv
Ukraine
Competing Interests:
Ukraine
MD, PhD, Senior Researcher in Age endocrinology department
Competing Interests:
Автор заявляет об отсутствии конфликта интересов, связанных с данной рукописью
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Tikhonova T.M. A mathematical model for stratification of LADA risk groups. Diabetes mellitus. 2014;17(1):15-20. (In Russ.) https://doi.org/10.14341/DM2014115-20
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