Особенности сахарного диабета в пожилом возрасте и принципы терапии

В настоящее время меется широкий выбор препаратов для эффективного и безопасного лечения сахарного диабета типа 2 в пожилом возрасте, позволяющего снизить риск развития и прогрессирования сосудистых осложнений, увеличить продолжительность и повысить качество жизни.

пожилой возраст, терапия, сахарный диабет

1. Справочник по диагностике и лечению заболеваний у пожилых /Под ред. Л.И. Дворецкого, Л.Б. Лазебника. M.: Новая Волна, Оникс, 2000.

2. Старостина Е.Г., Древаль А.В. Бигуаниды в лечении сахарного диабета. - М.: Мед.практика, 2000

3. Титов С.А., Крутько В.Н. Современные представления о механизмах старения (Обзор). //Физиология человека. 1996. -Т.22. -N2. -c.l 18-123.

4. Хорошина Л.П. Особенности питания людей старших возрастных групп. / / Клиническая геронтология. 2000.- №3-4. -с.54-61.

5. Чеботарев Д.Ф. Особенности лекарственной терапии в пожилом возрасте: Методические рекомендации. М.,1982. -34 с.

6. Abraria С, Duckworth W., McCarren М. et al. Desing of cooperative study on glycemic control and complication in diabetes mellitus type 2 Veterans Affairs Diabetes Trial / / J Diabetes Complications. - 2003; 17: 314-322.

7. Bruse D.G., Davis W.A., Davis T.M. Glycemic control in older subjects with type 2 diabetes mellitus in the Fremantle Diabetes Study. / / J Am Geriatr Soc-2000; 48(1 1): 1449-1453.

8. Burge M.R., Sobhy T.A., Quails C.R., Schade D.S. Effect of short-term . glucose control on glycemic thresholds for epinephrine and hypoglycemic symptoms. / / J Clin Endocrinol Metab. -2001; 86(1 1): 5471-5478.

9. California Healthcare Foundation/ American Geriatrics Society Panel on Improving Care for Elders with Diabetes. Guidelines for Improving the care of the older person with diabetes mellitus / / J Am Geriatr Soc-2003; 51:S265-280.

10. Castaneda C, Layne J.E., Munoz-Orians L. et al. A randomized controlled trial of resistance exercise training to improve glycemic control in older adults with type 2 diabetes. / / Diabetes Care.-2002; 25(12):2335-2341.

11. Droin P. Diamicron MR once daily is effective and well tolerated in type 2 diabetes: double-blind, randomized, multinational study. / / J Diabetes Complications. - 2000; 14(4): 185-191.

12. Elahi D., Muller D.C. Carbohydrate metabolism in the elderly. / / Eur J Clin Nutr. - 2000; 54 Suppl 3: SI 12-120.

13. Janson J., Laedtke Т., Parisi J.E. et al. Increased risk of type 2 diabetes in Alzheimer disease. / / Diabetes. - 2004; 53(2):474-481.

14. Jasik M., Rasperska-Czyzykowa Т., Karnafel W. et al. Evaluation of efficacy, safety and tolerance of glimepiride (Amaryl) in patients with type 2 diabetes / / Przegl Lek .-2000; 57, Suppl 4:23-27.

15. Henderson J.N., Allen K.V., Dearly I.J., Frier B.M. Hypoglycemia in insulin-treated Type 2 diabetis: freguency, symptoms and impaired awareness. / / Diabet Med. - 2003; 20( 12): 101 6-1021.

16. Holstein A., Plaschke F., Egberts E.H. Lower incidence of severe hypoglycaemia in patients with type 2 diabetes treated with glimepiride versus glibenclamid. / / Diabetes Metab Res Rev.-20001; 17(6): 467-473.

17. Geerlings S.E., Stolk R.P., Camps M.J. et al. Asymptomatic bacteriuria may be a complication in women with diabetes. / / Diabetes Care.- 2000; 23(6):744-749.

18. Gregori F., Ambrosi F., Manfrini S. et al. Poorly controlled elderly Type 2 diabetic patients: the effects of increasing sulphonylurea dosages or adding metformin. / / Diabet/ Med. -1999; 160 2): 1016-1024.

19. Koivhto V.A. Insulin treatment in Type II diabetes / / Diabetes.- 1993;16(Suppl 3):29-39.

20. КхллкЛо J., fA-yWuaneti 1., Р-услсАа К., Loatao W,. Hon- depended diabetes and its metabolic control are important predictors of stroke in elderly subjects. / / Stroke. - 1994; 25(6): 1157-1 164

21. Lodroscino G., Kang J.h., Grodstein F. Prospective study of type 2 diabetes and cognitive decline in women aged 70-81 years.// BMJ.- 2004; 3(6):328-548.

22. Lustman P, Clouse R, Freedland K. Management of major depression in adults with diabetes. Implications of recent clinical trials.// Semin Clin Neuropsychiatry.- 1998; 3: 102-1 14.

23. Misra A. Insulin treatment in non- insulin dependent diabetes mellitus / / The national Medical Journal of lndia.-1995; 8(4):169-177.

24. Meneilly G.S., Dawson K., Tessier D. Alteretion ih glucose metabolism in elderly patients with diabetes. // Diabetes Care.-l 993; 16(9):1241 -1248.

25. Meneilly G.S., Ryan E.A., Radziuk J et al. Effect of acarbose on insulin sensitivity in patients with diabetes. / / Diabetes Care.-2000; 23(8):1 162-1167

26. Najeed S.A., Khan I.A., Molnar J., Somberg J.C. Differential of glyburide (glibenclamidi) and metformin on QT dispersion a potential adenosine triphosptate sensitive K+ channel effect. / / Am J Cardiol.-2002; 90(10): 1103-1106.

27. Naor M., Steingruber H.J., Westhoff K. et al. Congitive function in elderly non- insulin-dependent diabetic patients before and after inpatient treatment for metabolic control. / / J Diabetes Complications. - 1997; 11(1): 40-46.

28. Oiknine R., Mooradian A.D. Drug therapy of diabetes in the elderly / / Biomed Pharmacother.-2003; 57(5-6):231-239.

29. Olson D.E., Norris. Diabetes in older adults. Overview of AGS guidelines for the treatment of diabetes mellitus in geriatric population/ //Geriatrics.- 2004; 59(4): 18-24.

30. Robert M.W. Hypoglycemia: still a risk in the elderly. / / Geriatrics. - 1990; 45(3): 69-75.

31. Ruigomez A., Rodrigues L.A. Presence of diabetes related complication at the time of NIDDM diagnosis: an important prognostic factor / / Eur. J. Epidemiol. . - 1 998; 14(15): 439 -445.

32. Shorr R.I., France L.V., Resnick H.E. et al. Glycemic control of older adults with type 2 diabetes: findinds from the Third National Health and Nutrition Examination Survey, 1988-1994. / / J Am Geriatr Soc-2000; 48(3):264-267

33. Sinclair A.J., Coll J. Diabetes in old age- changing concept in the secondary care arena. / / Coll. Physiacian London. 2000; 354( 1 ):240-244.

34. Ubink-Veltman L.J., Bilo H.J., Groenier K.H. et al. Prevalens, incidence and mortality of type 2 diabetes mellitus revisited: a prospective populacion-based study in the Nefterlands (ZODIAC-1).// Eur JEpidemiol.-2003; 1 8(8):793-800.

35. Velussi M. Lispro insulin treatment in comparision with regular human insulin in type 2 diabetic patients living in nursing homes. / / Diabetes Nutr Metab.-2002; 15(2): 96-100.

36. Wolffenbuttel B.H., Sels J.P., Rondas-Colbers G.J. et al. Comparison of different insulin regimens in elderly patients with NIDDM. / / Diabetes Care.-l 996; 19(12):1 326-1332.

37. Worrall G.j., Chaulk P.S., Moulton N. Congitive function fnd glycosylated hemoglobin in older with type 1 1 diabetes. / / J Diabetes Complications. - 1996; 10(6): 320-324.

38. Yki-Jarvinen H., Dressier A., Ziemen M. Less nostural hypoglycemia and better post-dinner glucose control with bedtime insulin glargine compared, vuth. bedtime NPH during, insulin combination therapy in type 2 diabetes. HOE 901/3002 Study Group. / / Diabetes Care.-2000; 23(8):1 130-1 136.