MODY3 in the child with type 2 diabetes mellitus phenotype: case report
https://doi.org/10.14341/2072-0351-3762
Abstract
MODY is a heterogeneous group of diseases that stem from certain genetic mutations and are characterized by beta-cell dysfunction, early clinical onset (before the age of 25) and autosomal dominant inheritance. Nowadays many studies address atypical variants of diabetes mellitus (DM) and consequential problems in differential diagnosis. Though generally patients with MODY have normal body weight, the ongoing spread of obesity will probably produce comorbid forms and thus alter clinical picture. We present a case of DM in a 13-year-old patient that characterizes development of MODY3 in type 2 DM-like phenotype.
About the Authors
Tamara Leonidovna Kuraeva
Endocrinology Research Centre, Moscow
prof., d.m.n., zav. otdeleniem diabeta Instituta detskoy endokrinologii
Elena Alexandrovich Sechko
Endocrinology Research Centre, Moscow
klinicheskiy ordinator Instituta detskoy endokrinologii
Irina Alexandrovna Eremina
Endocrinology Research Centre, Moscow
aspirant Instituta detskoy endokrinologii
O N Ivanova
Endocrinology Research Centre, Moscow
k.b.n., v.n.s. laboratorii genetiki i klinicheskoy immunologii
Sergey Alexandrovich Prokof’ev
Endocrinology Research Centre, Moscow
k.b.n.
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Review
For citations:
Kuraeva T.L., Sechko E.A., Eremina I.A., Ivanova O.N., Prokof’ev S.A. MODY3 in the child with type 2 diabetes mellitus phenotype: case report. Diabetes mellitus. 2013;16(2):88-93. (In Russ.) https://doi.org/10.14341/2072-0351-3762
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