Hyponatremia as acute adrenal insufficiency in patients with type 1 diabetes mellitus and kidney transplantation cause end-stage chronic kidney disease
I. S. Khagabanova,
O. K. Vikulova,
M. S. Shamkhalova,
E. A. Pigarova,
S. A. Martinov,
V. Y. Kalashnikov https://doi.org/10.14341/DM13163
Abstract
Diabetes mellitus type 1 (DM1) and chronic adrenal insufficiency (CAF) are among the most common autoimmune endocrine diseases that develop both isolated and in combination with each other and with other diseases of autoimmune origin, as part of various syndromes. At the same time, type 1 diabetes is quite often the first component of a systemic autoimmune lesion and acts as a predictor of the development of congenital disorder, which, in turn, against the background of type 1 diabetes, acquires a mild, sometimes atypical course, which complicates the diagnosis and prescription of therapy. The clinical case describes a patient with type 1 diabetes and end-stage chronic kidney disease (CKD), kidney allotransplantation (ART), who was on triple immunosuppressive therapy, who developed CHN, which was manifested by severe hyponatremia and the occurrence of frequent hypoglycemic conditions.
About the Authors
I. S. Khagabanova
Endocrinology Research Centre
Russian Federation
Russian Federation
Ilona S. Khagabanova, MD, PhD student
11 Dm. Ulyanov street, 117036 Moscow
O. K. Vikulova
Endocrinology Research Centre
Russian Federation
Russian Federation
Olga K. Vikulova, MD, PhD, Associate Professor
Scopus Author ID: 8697054500
Moscow
M. S. Shamkhalova
Endocrinology Research Centre
Russian Federation
Russian Federation
Minara S. Shamkhalova, MD, PhD
Moscow
E. A. Pigarova
Endocrinology Research Centre
Russian Federation
Russian Federation
Ekaterina A. Pigarova, MD, PhD
Moscow
S. A. Martinov
Endocrinology Research Centre
Russian Federation
Russian Federation
Sergey A. Martynov, MD, PhD
Moscow
V. Y. Kalashnikov
Endocrinology Research Centre
Russian Federation
Russian Federation
Viktor Y. Kalashnikov, MD, PhD, Professor
Moscow
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For citations:
Khagabanova I.S., Vikulova O.K., Shamkhalova M.S., Pigarova E.A., Martinov S.A., Kalashnikov V.Y. Hyponatremia as acute adrenal insufficiency in patients with type 1 diabetes mellitus and kidney transplantation cause end-stage chronic kidney disease. Diabetes mellitus. 2024;27(3):295-301. (In Russ.) https://doi.org/10.14341/DM13163
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