Risk factors for diabetic autonomic cardiovascular neuropathy in children and adolescents with type 1 diabetes mellitus
https://doi.org/10.14341/2072-0351-821
Abstract
Aim.
To determine risk factors for diabetic autonomic cardiovascular neuropathy (DACN) and to optimize diagnostic procedures for children and adolescents with type 1 diabetes mellitus.
Materials and methods.
Heart rate variability (HRV) was assessed in 101 subjects with type 1 diabetes mellitus aged 5?17 y.o. in 4 functional tests. Subjects with 3 positive tests out 4 were considered positive for DACN.
Results.
Increased glycemic variability (9+ mmol/l per day), regular hypoglycemic events and late diabetes complications were found to be DACN risk factors in children and adolescents.
Conclusions.
A diagnostic algorithm for DACN in children and adolescents with type 1 diabetes mellitus based on orthostatic HRV variability assessment shows high sensitivity and efficiency.
To determine risk factors for diabetic autonomic cardiovascular neuropathy (DACN) and to optimize diagnostic procedures for children and adolescents with type 1 diabetes mellitus.
Materials and methods.
Heart rate variability (HRV) was assessed in 101 subjects with type 1 diabetes mellitus aged 5?17 y.o. in 4 functional tests. Subjects with 3 positive tests out 4 were considered positive for DACN.
Results.
Increased glycemic variability (9+ mmol/l per day), regular hypoglycemic events and late diabetes complications were found to be DACN risk factors in children and adolescents.
Conclusions.
A diagnostic algorithm for DACN in children and adolescents with type 1 diabetes mellitus based on orthostatic HRV variability assessment shows high sensitivity and efficiency.
About the Authors
Maria Rustemovna Shaidullina
Kazan State Medical University, Kazan; Republican Children Hospital, Kazan
Russian Federation
Russian Federation
Farida Vadutovna Valeeva
Kazan State Medical University, Kazan
Russian Federation
Russian Federation
Eduard Zakirzyanovich Yakupov
Kazan State Medical University, Kazan
Russian Federation
Russian Federation
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Review
For citations:
Shaidullina M.R., Valeeva F.V., Yakupov E.Z. Risk factors for diabetic autonomic cardiovascular neuropathy in children and adolescents with type 1 diabetes mellitus. Diabetes mellitus. 2013;16(3):84-89. (In Russ.) https://doi.org/10.14341/2072-0351-821
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