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Сахарный диабет

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Особенности поражения артерий нижних конечностей и клинические исходы эндоваскулярных вмешательств у больных сахарным диабетом с критической ишемией нижних конечностей и хронической болезнью почек

https://doi.org/10.14341/DM2013485-94

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Аннотация

Цель. Оценить выраженность кальциноза артерий нижних конечностей, проанализировать отдаленные результаты чрескожной транслюминальной баллонной ангиопластики (ЧТБА) и клинические исходы у пациентов с сахарным диабетом (СД), критической ишемией нижних конечностей (КИНК) и хронической болезнью повек (ХБП).
Материалы и методы. У 48 пациентов без ХБП и 46 пациентов с ХБП и КИНК проведена бесконтрастная мультиспиральная компьютерная томография (МСКТ) нижних конечностей для количественной оценки степени кальциноза артерий голени, анализ отдаленных исходов ЧТБА артерий нижних конечностей.
Результаты. Отдаленные клинические исходы ЧТБА достоверно хуже в группе пациентов с ХБП, чем у лиц без ХБП. Тем не менее, сохранение конечности и выживаемость обследуемых групп  пациентов за 2-летний период наблюдения достигают удовлетворительных значений, 74% и 72% соответственно.
Выводы. Несмотря на технические трудности ЧТБА у больных СД, КИНК с нарушением выделительной функции почек, эндоваскулярное вмешательство позволяет избежать высокой ампутации конечности и повысить выживаемость в большинстве случаев.

Об авторах

Наталья Леонидовна Аюбова
ФГБУ Эндокринологический научный центр Минздрава России, Москва
Россия
аспирант отделения диабетической стопы, Институт диабета


Ольга Николаевна Бондаренко
ФГБУ Эндокринологический научный центр Минздрава России, Москва
Россия
кандидат медицинских наук, ведущий научный сотрудник, отделение диабетической стопы, Институт диабета


Гагик Радикович Галстян
ФГБУ Эндокринологический научный центр Минздрава России, Москва
Россия
доктор медицинских наук, профессор, заведующий отделением диабетической стопы, Институт диабета


Оксана Владимировна Манченко
ФГБУ Эндокринологический научный центр Минздрава России, Москва
Россия
кандидат медицинских наук, научный сотрудник отделения лучевой диагностики


Иван Иванович Дедов
ФГБУ Эндокринологический научный центр Минздрава России, Москва
Россия
доктор медицинских наук, профессор, академик РАН и РАМН, директор ФГБУ ЭНЦ


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Для цитирования:


Аюбова Н.Л., Бондаренко О.Н., Галстян Г.Р., Манченко О.В., Дедов И.И. Особенности поражения артерий нижних конечностей и клинические исходы эндоваскулярных вмешательств у больных сахарным диабетом с критической ишемией нижних конечностей и хронической болезнью почек. Сахарный диабет. 2013;16(4):85-94. https://doi.org/10.14341/DM2013485-94

For citation:


Ayubova N.L., Bondarenko O.N., Galstyan G.R., Manchenko O.V., Dedov I.I. Clinical outcomes of lower limb peripheral vascular disease after endovascular intervention in patients with diabetes mellitus, critical limb ischemia and chronic kidney disease. Diabetes mellitus. 2013;16(4):85-94. (In Russ.) https://doi.org/10.14341/DM2013485-94

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