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Arterial diseases of lower extremities in diabetic patients: current state and prospects of therapy

https://doi.org/10.14341/2072-0351-6253

Abstract

Peripheral artery diseases (PAD) are most serious diabetic complications responsible for the high risk of amputation of lower extremities. The occurrenceof PAD in diabetic patients is much higher than in subjects with undisturbed carbohydrate metabolism. PAD in diabetic patients is frequentlyan asymptomatic condition affecting distal portions of arterial segments and associated with pronounced mediacalcinosis. Standard diagnostic proceduresfor the screening of arterial lesions must be supplemented by non-invasive visualization and measurement of transcutaneous oxygen tensionin patients at risk of PAD and persisting foot ulcers. Of special importance is early diagnosis of critical limb ischemia and prevention of foot lesions.Combined treatment of diabetic foot syndrome in patients with critical limb ischemia includes normalization of foot circulation, surgical interventionand conservative therapy of the wound, monitoring concomitant micro- and macrovascular diabetic complications?

About the Authors

Gagik Radikovich Galstyan
Endocrinology Research Centre, Moscow


Alla Yur'evna Tokmakova
Endocrinology Research Centre, Moscow


Olga Nikolaevna Bondarenko
Endocrinology Research Centre, Moscow


Ivan Ivanovich Sitkin
Endocrinology Research Centre, Moscow


Kira Yur'evna Pryakhina
Endocrinology Research Centre, Moscow


Valeriy Afanas'evich Mitish
Endocrinology Research Centre, Moscow


Lyubov' Petrovna Doronina
Endocrinology Research Centre, Moscow


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Review

For citations:


Galstyan G.R., Tokmakova A.Yu., Bondarenko O.N., Sitkin I.I., Pryakhina K.Yu., Mitish V.A., Doronina L.P. Arterial diseases of lower extremities in diabetic patients: current state and prospects of therapy. Diabetes mellitus. 2011;14(1):74-80. (In Russ.) https://doi.org/10.14341/2072-0351-6253

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ISSN 2072-0351 (Print)
ISSN 2072-0378 (Online)