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Diabetic retinopathy. Results of international multicentre studies

https://doi.org/10.14341/2072-0351-6021

Abstract

Diabetic retinopathy (DR) is a main cause of blindness throughout the world, with chronic hyperglycemia and arterial hypertension being the keycontributors to the development of this microvascular complication. A few international multicentre studies have recently been conducted to assesseffect of intensive control of glycemia and AH on the development and progress of DR in type 1 and 2 DM patients. Results of DCCT, UKPDS,DIRECT, ADVANCE, and AdREM studies are reviewed.

About the Author

Olga Mikhailovna Smirnova
Endocrinological Research Centre, Moscow


References

1. Fong D.S., Aiello L., Gardner T.W., Berman E.R. et.al. Retinipathy in Diabetes // Diabetes Care. - 2004. - Vol.27, Suppl. 1, Jan. - P. S84- 87.

2. Cмирнова О.М. Диабетическая ретинопатия. Современные проблемы // Сахарный диабет. - 2008. - 3. - С.12-15.

3. The Diabetes Control and Complications Trial Research Group // New Engl. J. Med. - 1993. - 329. - Р. 977-986.

4. Stratton I.M., Kohner E.M., Aldington S.J. et.al. UKPDS 50: Risk factors for incidence and progression of retinopathy in Tipe II diabetes over 6 years frim diagnosis // Diabetiligia. - 2001. - 44. - Р. 156- 163.

5. Grading Diabetic Retinopathy from Stereoscopic Color Fundus Photographs - An Extension of the Modified Airlie House Classification. ETDRS Report Number 10 // Ophtalmology. - 1991. - May. Vol. - S786-806.

6. Sjolie A.K., Klein R., Porta M., et al. DIRECT Programme Study Group. Effect of Candesartan on progression and regression retinopathy in type 2 diabetes (DIRECT- Protect 2): a randomised placebo-controlled trial. // Lancet. - 2008. - 372. - Р. 1385-1393.

7. Shichiri M., Kishikawa H., Ohkubo Y., Wake N. Long-term Results of Kumamoto Study on Optimal Diabetes Control in Type 2 Diabetes Patients // Diabetes Care. - 2000. - 23. Suppl.2. - P. B21-B29.

8. Смирнова О.М. Цели и задачи исследования ADVANCE. Дизайн ис- следования. Обоснование применения Диабетона МВ // Сахарный диабет. - 2009. - №2. - С. 6-10.

9. Beulens J.W., Patel A., Vingerling J.R., Cruickshank J.K., Hughes A.D., Stanton A., Lu J., McG Thom S.A,. Grobbee D.E., Stolk R.P. Effects of blood pressure lowering and intensive glucose control on the incidents end progression of retinopathy in patients with type 2 diabetes mellitus: a randomized controlled trial // Diabetologia. - 2009. - 10. - P. 2027-2036.


Review

For citations:


Smirnova O.M. Diabetic retinopathy. Results of international multicentre studies. Diabetes mellitus. 2010;13(1):80-87. (In Russ.) https://doi.org/10.14341/2072-0351-6021

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ISSN 2072-0351 (Print)
ISSN 2072-0378 (Online)