The role of apoptosis in pathogenesis of type 1 diabetes mellitus
https://doi.org/10.14341/2072-0351-6016
Abstract
Type 1 diabetes mellitus (DM1) is known to be associated with progressive destruction of pancreatic beta-cells. Apoptosis plays the key role in this destructiveprocess. The paper focuses on major mechanisms underlying activation of beta-cell apoptosis and its role in regulation of immune processes inpatients with DM1.
About the Authors
Elena Vladimirovna Pekareva
Endocrinological Research Centre, Moscow
Tatiana Vasil'evna Nikonova
Endocrinological Research Centre, Moscow
Olga Mikhailovna Smirnova
Endocrinological Research Centre, Moscow
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Review
For citations:
Pekareva E.V., Nikonova T.V., Smirnova O.M. The role of apoptosis in pathogenesis of type 1 diabetes mellitus. Diabetes mellitus. 2010;13(1):45-49. (In Russ.) https://doi.org/10.14341/2072-0351-6016
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