Pancreatogenic diabetes mellitus: incidence and detection rate analysis
https://doi.org/10.14341/2072-0351-5820
Abstract
The article addresses incidence and causes of belated diagnostics of pancreatogenic diabetes mellitus (DM).
Materials and methods.
In 367 patients with chronic biliary or alcoholic pancreatitis (CP) glycemia and glycated hemoglobin HbA1c levels were testedin order to detect a metabolic disorder (DM or impaired glucose tolerance).
Results.
We observed positive correlation between duration of CP (1 to 10 years) and incidence of DM, with the latter being 3 to 5 times greater inpatients with 10 years of CP experience. During remission period 44,8% of patients were not aware of development of DM. In more than 80% ofpatients CP was diagnosed during admission for exacerbation of DM.
Conclusion.
Low detection rates of pancreatogenic DM is largely due to insufficient risk awareness of patients as well as inadequate attention of medicalpractitioners to the problem of CP and DM comorbidity.
About the Authors
Marina Alekseevna KunitsynaElena Igorevna Kashkina
References
1. М.Ю. Дробижев, Е.В. Суркова, О.Г. Мельникова Эпидемиология сахар- ного диабета у больных, наблюдающихся терапевтами, кардиологами, неврологами // Consilium medicum. - 2008. - ?12. - С. 92-96.
2. Маев, И.В. Хронический панкреатит / И.В. Маев, А.Н. Казюлин, Ю.А. Кучерявый. - М.: Медицина, 2005. - 504 с.
3. Губергриц Н.Б., Лукашевич Г.М., Голубова О.А. и др. Панкреатогeнный сахарный диабет // Рос. журн. гастроэнтерол., гепатол. колопроктол. - 2007. - Т. 17, ?6. - С. 12-16.
4. Тучина Л.М. Распространенность заболеваний поджелудочной железы среди населения г. Москвы / Л.М. Тучина, Г.Г. Порошенко // Рос. Га- строэнтерол. журн. - 2001. - ?2. - С. 154.
5. Губергриц Н.Б., Лукашевич Г.М., Голубова О.А. и др. Что нужно знать гастроэнтерологу о сахарном диабете третьего типа // Здоровье Укра- ины. - 2007. - ?7/1. - С. 14-15.
6. Malka D., Hammel P., Sauvanet A. et al. Acinar-islet cell interactions: Diabetes mellitus in chronic pancreatitis // Gastroenterology. - 2000. - Vol. 119. - P. 1324-1332.
7. Amadife M.U., Muogbo D.C. Chronic calcific pancreatitis presenting with stunting and diabetes mellitus //Niger. J. Clin. Pract. - 2008. - Vol. 11, ?3. - P. 254-246.
8. Buchle M.W.r, Uhl W., Malfertheiner P. et al. Diseases of the pancreas. - Basel; Freiburg; Paris:Karger, 2004. - 212 p.
9. Koizumi M., Yoshida Y., Abe N. et al. Pancreatic diabetes in Japan // Pancreas. - 1998. - Vol. 16. - P.385-391.
10. Ewald N., Kaufmann C., Raspe A. et al. Prevalence of diabetes mellitus secondary to pancreatic disease (type 3c) // Pancreatology. - 2006. - Vol.6. - P. 393.
Review
For citations:
Kunitsyna M.A., Kashkina E.I. Pancreatogenic diabetes mellitus: incidence and detection rate analysis. Diabetes mellitus. 2011;14(4):65-67. (In Russ.) https://doi.org/10.14341/2072-0351-5820

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