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National Council of Experts: the place of DPP-4 inhibitors in the treatment of patients with type 2 diabetes mellitus

https://doi.org/10.14341/DM13110

Abstract

TThe annual increase in the prevalence of type 2 diabetes mellitus emphasizes the relevance of the search for new treatment options, along with necessity for regular review of proven therapeutic solutions. Today, dipeptidyl peptidase-4 inhibitors (DPP-4i, gliptins) are effective and safe hypoglycemic therapy, which is included in modern standards of treatment of type 2 diabetes. In 2022, the availability of this group of drugs for Russian patients has significantly increased. This circumstance became a prerequisite for holding a National Council of Experts with the participation of members of the Russian Association of Endocrinologists. The task of the Council was to determine the place of DPP-4i in the treatment of patients with type 2 diabetes in 2023. During the meeting of the Council, experts summarized the evidence base of DPP-4i taking into account the latest scientific data and determined the optimal clinical portraits of patients for the use of DPP-4i in accordance with updated national recommendations.

About the Authors

M. V. Shestakova
Endocrinology Research Centre
Russian Federation

Marina V. Shestakova, MD, PhD, Professor, Academician of the Russian Academy of Sciences

Researcher ID: HKO-5485-2023;
Scopus Author ID: 7004195530

11 Dm. Ulyanova street, 117036 Moscow



G. R. Vagapova
Kazan State Medical Academy
Russian Federation

Gulnar R. Vagapova, MD, PhD, Professor

Researcher ID: C-1421-2019;
Scopus Author ID: 56663181000

Kazan



O. K. Vikulova
Endocrinology Research Centre
Russian Federation

Olga K. Vikulova, MD, PhD, Associate Professor

Scopus Author ID: 8697054500

Moscow



G. R. Galstyan
Endocrinology Research Centre
Russian Federation

Gagik R. Galstyan, MD, PhD, Professor

Researcher ID: B-5925-2017;
Scopus Author ID: 6701438348

Moscow



T. Yu. Demidova
Pirogov Russian National Research Medical University
Russian Federation

Tatiana Y. Demidova, MD, PhD, Professor

Researcher ID: D-3425-2018;
Scopus Author ID: 7003771623

Moscow



E. N. Dudinskaya
Pirogov Russian National Research Medical University
Russian Federation

Ekaterina N. Dudinskaya, MD, PhD

Researcher ID: H-3281-2013;
Scopus Author ID: 55308206900

Moscow



T. P. Kiseleva
Ural State Medical University
Russian Federation

Tatiana P. Kiseleva, MD, PhD, Professor

Scopus Author ID: 57340680000

Ekaterinburg



A. M. Mkrtumyan
A.I. Yevdokimov Moscow State University of Medicine and Dentistry
Russian Federation

Ashot M. Mkrtumyan, MD, PhD, Professor

Scopus Author ID: 6602962407

Moscow



N. A. Petunina
I. M. Sechenov First Moscow State Medical University
Russian Federation

Nina A. Petunina, MD, PhD, Professor 

Researcher ID: P-7717-2015;
Scopus Author ID: 6603436552

Moscow



O. N. Tkacheva
Pirogov Russian National Research Medical University
Russian Federation

Olga N. Tkacheva, MD, PhD, Professor

Researcher ID: P-7717-2015;
Scopus Author ID: 6603436552

Moscow



V. V. Fadeev
I. M. Sechenov First Moscow State Medical University
Russian Federation

Valentin V. Fadeev, MD, PhD, Professor

Scopus Author ID: 7005742629

Moscow



Y. S. Khalimov
Health Committee of the Government of St. Petersburg
Russian Federation

Iurii S. Khalimov, MD, PhD, Professor

Scopus Author ID: 55531165300

Saint Petersburg



E. A. Shestakova
Endocrinology Research Centre
Russian Federation

Ekaterina A. Shestakova, MD, PhD, leading research associate

Researcher ID: N-8409-2014;
Scopus Author ID: 55554041400

Moscow



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Supplementary files

1. Figure 1. Level of glycated hemoglobin on various treatment regimens with dipeptidyl peptidase type 4 inhibitors in the Russian Federation as of 01/01/23 (Data from the Federal Register of Diabetes Mellitus).
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Shestakova M.V., Vagapova G.R., Vikulova O.K., Galstyan G.R., Demidova T.Yu., Dudinskaya E.N., Kiseleva T.P., Mkrtumyan A.M., Petunina N.A., Tkacheva O.N., Fadeev V.V., Khalimov Y.S., Shestakova E.A. National Council of Experts: the place of DPP-4 inhibitors in the treatment of patients with type 2 diabetes mellitus. Diabetes mellitus. 2023;26(6):619-625. (In Russ.) https://doi.org/10.14341/DM13110

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ISSN 2072-0351 (Print)
ISSN 2072-0378 (Online)