Features of diagnostics and treatments of the patient with type 2 diabetes mellitus and chronic ischtmia with threating lower limb loss
https://doi.org/10.14341/DM13038
Abstract
The article presents the result of our own observation of the patient with a poor control of type 2 diabetes mellitus (DM) for a long period, complicated by obliterating atherosclerosis of the arteries of the lower extremities, Menckeberg’s sclerosis and chronic ischemia threatening loss of the lower extremity (CLLI). A feature of the clinical manifestation are complications associated with potentially regional (angiosomal) ischemia of the foot, as well as variant anatomy, represented by hypoplasia of the vascular lower leg in the patient. The clinical consequences of vascular calcification due to long-term decompensation of carbohydrate metabolism and the development of diabetic distal polyneuropathy (DDP) led to falsely high values of the cuff test in the patient. Disadvantages of non-invasive methods for diagnosing limb ischemia and advantages of the complex application of tests for diseases of the arteries of the lower extremities are discussed. Using WIFI classification according to the degree of ulceration, the degree of ischemia, and the degree of infection on the foot (Wound, Ischemia and Foot Infection), the tactics of managing the patient are presented. The important role of ultrasonic duplex scanning (USDS) in the visualization of the arteries of the legs and feet in patients with DM is substantiated. The importance of a multidisciplinary approach in the management of a comorbid patient with type 2 diabetes and CLTI is emphasized.
About the Authors
O. N. BondarenkoRussian Federation
Olga N. Bondarenko - MD, PhD, leading research associate.
11 Dm. Ulyanova street, 117036 Moscow
Competing Interests:
none
M. V. Yaroslavceva
Russian Federation
Marianna V. Yaroslavceva - MD, PhD, senior researcher.
Moscow
Competing Interests:
none
G. R. Galstyan
Russian Federation
Gagik. R. Galstyan - MD, PhD, Professor.
Moscow
Competing Interests:
none
V. A. Larina
Russian Federation
Valeria A. Larina - clinical resident.
Moscow
Competing Interests:
none
A. S. Petrosyan
Russian Federation
Albina S. Petrosyan - clinical resident.
Moscow
Competing Interests:
none
N. G. Mokrysheva
Russian Federation
Natalya G. Mokrysheva - MD, PhD, Professor.
Moscow
Competing Interests:
none
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Supplementary files
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1. Figure 1. Appearance of the foot upon admission to the hospital. | |
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2. Figure 2. Ultrasound duplex scanning of the arteries of the lower extremities upon admission. | |
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3. Figure 3. Radiograph. Osteomyelitis of the heads of the 4th and 5th metatarsals. | |
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4. Figure 4. Condition after disarticulation of the 4th toe of the right foot on 08/06/22, resection of the heads of the 4th and 5th metatarsal bones on 08/19/22. | |
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5. Figure 5. Intraoperative X-ray contrast angiography before mechanical recanalization and balloon angioplasty in the lateral projection (slow and weak filling of the arteries of the foot with contrast), lateral projection. | |
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6. Figure 6. X-ray contrast angiography of the arteries of the right lower limb before and after revascularization. | |
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7. Figure 7. Control ultrasound duplex scanning of the arteries of the lower extremities. | |
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8. Figure 8. Condition of the wound of the right lower limb: a — on the 2nd day after surgery, b — 5 weeks after surgery. | |
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Review
For citations:
Bondarenko O.N., Yaroslavceva M.V., Galstyan G.R., Larina V.A., Petrosyan A.S., Mokrysheva N.G. Features of diagnostics and treatments of the patient with type 2 diabetes mellitus and chronic ischtmia with threating lower limb loss. Diabetes mellitus. 2024;27(2):185-195. (In Russ.) https://doi.org/10.14341/DM13038

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