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Diabetes mellitus type 1 and coronary artery disease with severe systolic heart failure in 25 year-old adult

https://doi.org/10.14341/DM12865

Abstract

Diabetes mellitus (DM) type 1 accounts for up to 90% of all cases of diabetes among children, adolescents and young adults (10 % are represented by T2DM, MODY, etc.). DM is characterized not only by glucose metabolism disorder, but also by abnormal protein and lipid metabolism, leading to severe macrovascular complications. A clinical case of diabetes type 1, hyperlipidemia, coronary artery disease (CAD) and chronic heart failure (HF) in a 25-year-old adult has been demonstrated. The medical examination revealed lipid metabolism disorders, multivessel coronary artery disease, which required myocardial revascularization, and severe heart failure with a reduced ejection fraction (HFrEF). The clinical case demonstrates that proper cardiovascular examination should be performed in all patients with diabetes and lipid disorders, regardless of age and type of diabetes. The authors also consider the use of sodium-glucose 

About the Authors

A. A. Voznesenskaya
Endocrinology Research Centre
Russian Federation

Anastasia A. Voznesenskaya - clinical resident; eLibrary SPIN: 9188-7450.

11 Dm. Ulyanova street, 117036 Moscow


Competing Interests:

none



I. Z. Bondarenko
Endocrinology Research Centre
Russian Federation

Bondarenko I.Z. - MD, PhD, leading research associate; eLibrary SPIN: 4524-4803

Moscow


Competing Interests:

none



K. V. Melkozerov
Endocrinology Research Centre
Russian Federation

Konstantin V. Melkozerov - MD, PhD; eLibrary SPIN: 5307-9820.

Moscow


Competing Interests:

none



R. S. Kosharnaya
Endocrinology Research Centre
Russian Federation

Raisa S. Kosharnaya – cardiologist.

Moscow


Competing Interests:

none



A. S. Zakharov
Endocrinology Research Centre
Russian Federation

Alexander S. Zakharov, endovascular surgeon; eLibrary SPIN: 7597-4979.

Moscow


Competing Interests:

none



M. Yu. Movsesyants
Endocrinology Research Centre
Russian Federation

Mikhail Yu. Movsesyants - MD, PhD; eLibrary SPIN: 3846-3746

Moscow


Competing Interests:

none



M. D. Kuklina
Endocrinology Research Centre
Russian Federation

Maria D. Kuklina - MD, PhD; eLibrary SPIN: 1077-5118.

Moscow


Competing Interests:

none



V. Yu. Kalashnikov
Endocrinology Research Centre
Russian Federation

Victor Yu. Kalashnikov - MD, PhD, Professor; eLibrary SPIN: 5342-7253.

Moscow


Competing Interests:

none



References

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Supplementary files

1. Figure 1. Right coronary artery.
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2. Figure 2. Anterior interventricular artery.
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3. Figure 3. Right coronary artery after stenting.
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4. Figure 4. Anterior interventricular artery after stenting.
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Type Исследовательские инструменты
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Review

For citations:


Voznesenskaya A.A., Bondarenko I.Z., Melkozerov K.V., Kosharnaya R.S., Zakharov A.S., Movsesyants M.Yu., Kuklina M.D., Kalashnikov V.Yu. Diabetes mellitus type 1 and coronary artery disease with severe systolic heart failure in 25 year-old adult. Diabetes mellitus. 2022;25(5):514-521. (In Russ.) https://doi.org/10.14341/DM12865

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ISSN 2072-0351 (Print)
ISSN 2072-0378 (Online)