Preview

Diabetes mellitus

Advanced search

Validation of the Finnish diabetes risk score (FINDRISC) for the Caucasian population of Siberia

Abstract

Aim. A validation of the Finnish diabetes risk score (FINDRISC) was conducted among the Siberian population. FINDRISC was used to study the prevalence of risk factors for type 2 diabetes mellitus (T2DM) and to estimate the incidence of T2DM in high-risk groups during a 10-year observation period. 

Materials and methods. A total of 9,360 subjects aged between 45 and 69 years were enrolled in this cross-sectional, population-based study. FINDRISC was used to group 8,050 people without diabetes according to their risk for T2DM. Statistical analysis was performed using SPSS. 

Results. When a cutoff point of 11 was used to identify those with diabetes, sensitivity was 76. 0% and specificity was 60. 2%. The area under the receiver operating curve for diabetes was 0. 73 (0. 73 for men and 0. 70 for women). More than one-third (31. 7%) of the adult population of Novosibirsk was estimated to have medium, high or very high risk of developing T2DM in the next 10 years. Cases of T2DM estimated to occur during the 10 years of follow-up had significantly higher incidence of risk factors such as BMI ≥30 kg/m2, waist circumference >102 cm in men and >88 cm in women and a family history of T2DM and were more likely to take drugs to lower blood pressure. 

Conclusion. FINDRISC provided good results in our sample, and we recommend its use in the Siberian population. 

About the Authors

Svetlana V. Mustafina
Institution of Internal and Preventive Medicine, Novosibirsk
Russian Federation
MD, PhD, Senior Researcher, Laboratory of clinical and population-based preventive and therapeutic research and endocrine diseases


Oksana D. Rymar
Institution of Internal and Preventive Medicine, Novosibirsk
Russian Federation
MD, PhD, Head of the Laboratory, Laboratory of clinical and population-based preventive and therapeutic research and endocrine diseases
Competing Interests: Федеральное государственное бюджетное научное учреждение «Научно-исследовательский институт терапии и профилактической медицины»


Olga V. Sazonova
Novosibirsk State Medical University, Novosibirsk
Russian Federation
MD, PhD, chief endocrinologist of the city, Associate Professor of Medical University «Novosibirsk State Medical University of Ministry of Health of Russia"


Liliya V. Shcherbakova
Institution of Internal and Preventive Medicine, Novosibirsk
Russian Federation
MD, PhD, Senior Researcher, Laboratory of clinical and population-based preventive and therapeutic research and endocrine diseases


Michail I. Voevoda
Institution of Internal and Preventive Medicine, Novosibirsk
Russian Federation
Corresponding Member of RAN, MD, PhD, director of the Institution of Internal and Preventive Medicine


References

1. IDF Diabetes Atlas. Sixth edition 2013; р. 160. URL: http://www.idf.org/sites/default/files/EN_6E_Atlas_Full_0.pdf

2. Никитин Ю.П., Симонова Г.И., Малахина Е.С., и др. Распространенность сахарного диабета у населения Сибири и Дальнего Востока. // Консилиум. – 1999. – №6 – С. 6-9. [Nikitin YP, Simonova GI, Malachina E. S., etc. Prevalence of diabetes among the population of Siberia and the Far East. Consilium. 1999;(6):6-9. (in Russ)]

3. Никитин Ю.П., Воевода М.И., Симонова Г.И. Сахарный диабет и метаболический синдром в Сибири и на Дальнем Востоке. // Вестник Российской академии медицинских наук. – 2012. – Т. 67. – №1. – С. 66-74. [Nikitin YP, Voevoda МI, Simonova GI. Diabetes mellitus and metabolic syndrome in Siberia and in the Far East. Annals of the Russian academy of medical sciences. 2012;67(1):66-74. (In Russ.)] DOI: 10.15690/vramn.v67i1.113

4. Herder C, Peltonen M, Koenig W, et al. Systemic immune mediators and lifestyle changes in the prevention of type 2 diabetes: results from the Finnish Diabetes Prevention Study. Diabetes. 2006;55(8):2340-2346. doi: 10.2337/db05-1320

5. Lindstrom J, Tuomilehto J. The Diabetes Risk Score: A practical tool to predict type 2 diabetes risk. Diabetes Care. 2003;26(3):725-731. doi: 10.2337/diacare.26.3.725.

6. Saaristo T, Peltonen M, Lindstrom J, et al. Cross-sectional evaluation of the Finnish Diabetes Risk Score: a tool to identify undetected type 2 diabetes, abnormal glucose tolerance and metabolic syndrome. DiabVasc Dis Res. 2005;2(2):67. doi: 10.3132/dvdr.2005.011

7. Noble D, Mathur R, Dent T, et al. Risk models and scores for type 2 diabetes: systematic review. BMJ. 2011;343:d7163. doi: 10.1136/bmj.d7163

8. Мустафина С.В., Симонова Г.И., Рымар О.Д. Сравнительная характеристика шкал риска сахарного диабета 2 типа // Сахарный диабет. – 2014. – Т. 17. – №3 – C. 17-22. [Mustafina SV, Simonova GI, Rymar OD. Comparative characteristics of diabetes risk scores. Diabetes mellitus. 2014;17(3):17-22. (in Russ)] doi: 10.14341/DM2014317-22

9. Bergmann A, Li J, Wang L, et al. A simplified Finnish diabetes risk score to predict type 2 diabetes risk and disease evolution in a German population. Horm Metab Res. 2007;39(9):677-682. doi: 10.1055/s-2007-985353

10. Zhang L, Zhang Z, Zhang Y, et al. Evaluation of Finnish Diabetes Risk Score in screening undiagnosed diabetes and prediabetes among U.S. adults by gender and race: NHANES 1999-2010. PLoS One. 2014;9(5):e97865. doi: 10.1371/journal.pone.0097865

11. Schmid R, Vollenweider P, Bastardot F, et al. Validation of 7 type 2 diabetes mellitus risk scores in a population-based cohort: CoLaus study. Arch Intern Med. 2012;172(2):188-189. doi: 10.1001/archinte.172.2.188

12. Robinson CA, Agarwal G, Nerenberg K. Validating the CANRISK prognostic model for assessing diabetes risk in Canada’s multi-ethnic population. Chronic Dis Inj Can. 2011;32(1):19-31.

13. Al-Lawati JA, Tuomilehto J. Diabetes risk score in Oman: a tool to identify prevalent type 2 diabetes among Arabs of the Middle East. Diabetes Res Clin Pract. 2007;77(3):438-444. doi: 10.1016/j.diabres.2007.01.013

14. Дедов И.И., Шестакова М.В., Галстян Г.Р., и др. Алгоритмы специализированной медицинской помощи больным сахарным диабетом. Под редакцией И.И. Дедова, М.В. Шестаковой (7-й выпуск) // Сахарный диабет. – 2015. – Т. 18. – №1S – C. 1-112. [Dedov II, Shestakova MV, Galstyan GR, et al. Standards of specialized diabetes care. Edited by Dedov I.I., Shestakova M.V. (7th edition). Diabetes mellitus. 2015;18(1S):1-112. (in Russ)] doi: 10.14341/DM20151S1-112

15. Peasey A, Bobak M, Kubinova R, et al. Determinants of cardiovascular disease and other non-communicable diseases in Central and Eastern Europe: rationale and design of the HAPIEE study. BMC Public Health. 2006;6:255. doi: 10.1186/1471-2458-6-255

16. Makrilakis K, Liatis S, Grammatikou S, et al. Validation of the Finnish diabetes risk score (FINDRISC) questionnaire for screening for undiagnosed type 2 diabetes, dysglycaemia and the metabolic syndrome in Greece. Diabetes Metab. 2011;37(2):144-151. doi: 10.1016/j.diabet.2010.09.006


Supplementary files

Review

For citations:


Mustafina S.V., Rymar O.D., Sazonova O.V., Shcherbakova L.V., Voevoda M.I. Validation of the Finnish diabetes risk score (FINDRISC) for the Caucasian population of Siberia. Diabetes mellitus. 2016;19(2):113-118. (In Russ.)

Views: 1832


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 2072-0351 (Print)
ISSN 2072-0378 (Online)