The combination of common neuroosteoarthropathy and diabetic dermatopathy in type 2 diabetes mellitus
Abstract
Diabetic neuroosteoarthropathy (Charcot’s osteoarthropathy, DNAP, Charcot’s foot) is a common complication of diabetic neuropathy, which can be easily diagnosed in clinical practice and usually is corrected without leading to severe deformation of the affected joint in case of timely and adequate treatment. We present the result of long-term clinical observation of a patient with early development of complications of type 2 diabetes mellitus, diabetic dermatopathy, common DNOAP with damage to the joints of the feet, ankles, knees and elbows. A feature of the described clinical case is the prevalence of osteoarticular disorders with seizure of atypical diabetes zones – knee and elbow joints, the defeat of which is more characteristic of other diseases (such as collagenoses and syphilis), as well as a combination of DNOAP with diabetic dermatopathy. It seems that the causes of such a common arthropathic process lie in the long course of diabetic neuropathy, which debuted long before the diagnosis of type 2 diabetes, as well as the development and progression of this patient in the last decade of observing diabetic nephropathy and associated secondary hyperparathyroidism. In the modern literature, descriptions of combinations of dermatopathies with other complications of diabetes mellitus are extremely rare, and references to a combination of common DNAP and diabetic bullosis have not been found.
About the Authors
Alla Yu. TokmakovaRussian Federation
PhD
Ekaterina S. Gracheva
Russian Federation
MD, clinical resident
Ekaterina L. Zaitseva
Endocrinology Research Centre
Russian Federation
MD, PhD
Alexandr V. Vorontsov
Russian Federation
ScD
References
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Supplementary files
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1. Fig. 1. Radiographs of the left knee joint, 1996 | |
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2. Fig. 2. X-ray of the left knee joint, made in lateral projection, 2009 | |
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3. Fig. 3. Radiographs of the ankle joints, 2004 | |
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4. Fig. 4. X-ray of both feet, 2016 | |
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5. Fig. 5. The appearance of the limbs upon admission. Foci of opening bullae in the middle third of the anterior surface of the legs | |
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6. Fig. 6. Appearance of deformation of the feet and knee joints. | |
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7. Fig. 7. X-ray of both feet upon admission, 2018 | |
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8. Fig. 8. Radiograph of both knee joints upon admission, 2018 | |
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9. Fig. 9. Radiographs of the elbow joints upon admission, 2018 | |
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Review
For citations:
Tokmakova A.Yu., Gracheva E.S., Zaitseva E.L., Vorontsov A.V. The combination of common neuroosteoarthropathy and diabetic dermatopathy in type 2 diabetes mellitus. Diabetes mellitus. 2020;23(2):201-208. (In Russ.)