Primenenie ubikhinona (koenzima Q) v kompleksnoy terapii sakharnogo diabeta i ego sosudistykh oslozhneniy
https://doi.org/10.14341/2072-0351-5865
Abstract
Изучение роли и значимости свободных радикалов в нарушении метаболизма позволило установить, что свободные радикалы кислорода участвуют в патогенезе почти 100 заболеваний, включая сахарный диабет и его сосудистые осложнения. Установлено, что при этих заболеваниях в мембранах и цитозоле клеток различных тканей выявляется повышенное содержание как свободных радикалов, так и продуктов их свободнорадикального окисления (альдегиды, кетоны, эпоксиды, гидроперекиси, диеновые и триеновые конъюгаты). Исследованиями подтверждено, что источниками образования свободных радикалов кислорода являются шесть путей метаболизма глюкозы.
About the Authors
Mikhail Ivanovich Balabolkin
ММА им. И.М.Сеченова, Москва
Elena Michailovna Klebanova
ММА им. И.М.Сеченова, Москва
Viktoriya Michailovna Kreminskaya
ММА им. И.М.Сеченова, Москва
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Review
For citations:
Balabolkin M.I., Klebanova E.M., Kreminskaya V.M. Primenenie ubikhinona (koenzima Q) v kompleksnoy terapii sakharnogo diabeta i ego sosudistykh oslozhneniy. Diabetes mellitus. 2007;10(4):37-42. (In Russ.) https://doi.org/10.14341/2072-0351-5865
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