On pathogenesis of arterial hypertension in type 2 diabetes mellitus
https://doi.org/10.14341/2072-0351-5635
Abstract
Aim.
To study the functional state of arterioles in patients with type 2 diabetes mellitus and concomitant arterial hypertension (AH) and evaluatethe role of sodium in mechanisms of elevation of arterial pressure (AP) in this pathology.
Materials and methods.
163 patients of whom 83 had DM2 with AH and 80 essential hypertension. They were examined by dopplerography of themicrocirclatory bed, measurement of arterial blood flow and daily sodium urinary excretion.
Results.
Patients with essential AH showed increased arteriolar circulation rate and enhanced reactivity of microvessels. These parameters werereduced in patients with DM2 and AH who consumed large amount of table salt.
Conclusion.
Mechanisms of development of essential AH and AH in DM2 are significantly different.
To study the functional state of arterioles in patients with type 2 diabetes mellitus and concomitant arterial hypertension (AH) and evaluatethe role of sodium in mechanisms of elevation of arterial pressure (AP) in this pathology.
Materials and methods.
163 patients of whom 83 had DM2 with AH and 80 essential hypertension. They were examined by dopplerography of themicrocirclatory bed, measurement of arterial blood flow and daily sodium urinary excretion.
Results.
Patients with essential AH showed increased arteriolar circulation rate and enhanced reactivity of microvessels. These parameters werereduced in patients with DM2 and AH who consumed large amount of table salt.
Conclusion.
Mechanisms of development of essential AH and AH in DM2 are significantly different.
About the Authors
Violen Stepanovich Volkov
Tver State Medical Academy, Tver
Evgenia Vladimirovna Rudenko
Tver State Medical Academy, Tver
Svetlana Anatol'evna Rokkina
Tver State Medical Academy, Tver
Olga Borisovna Poselyugina
Tver State Medical Academy, Tver
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Review
For citations:
Volkov V.S., Rudenko E.V., Rokkina S.A., Poselyugina O.B. On pathogenesis of arterial hypertension in type 2 diabetes mellitus. Diabetes mellitus. 2011;14(2):53-55. (In Russ.) https://doi.org/10.14341/2072-0351-5635
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