Use of dual action inhibitor (duloxetine) in diabetic neuropathy
https://doi.org/10.14341/2072-0351-5424
Abstract
Невропатическая боль при сахарном диабете имеет сложный характер и вызывается в отличие от ноцицептив- ной боли ? нарушениями как в периферической, так и центральной нервной системе. Накапливается все больше данных, свидетель- ствующих о целом спектре нарушений, включая изменения струк- туры и функции спинного мозга, тала мическую нейрональную дисфунк цию, снижение ингибиторного влияния нисходящих невро- нальных путей. Прогресс в изучении патогенеза невропатии открывает новые пути поиска препаратов, оказывающих непо- средственное влияние на патофизиологические механизмы боли. Применение у больных сахарным диабетом дулоксетина (симбал- ты) ? сбалансированного селективного двойного ингибитора обратного захвата серотонина и норадреналина, занимает важное место в комплексном лечении болевой диабетической невропатии
About the Author
Irina Vladimirovna Gur'eva
Федеральное бюро медико-социальной экспертизы, Москва; Российская медицинская академия последипломного образования, Москва
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Review
For citations:
Gur'eva I.V. Use of dual action inhibitor (duloxetine) in diabetic neuropathy. Diabetes mellitus. 2009;12(1):55-58. (In Russ.) https://doi.org/10.14341/2072-0351-5424
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