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Specific features of urogenital disorders in patents with diabetes mellitus

https://doi.org/10.14341/2072-0351-5396

Abstract

По данным Всемирной организации здравоохранения в настоящее время на планете насчитывается около 220 млн. больных СД, и их число прогрессивно растет. СД оказывает негативное влияние практически на все системы организма человека, в том числе и мочеполовую. С одной сто- роны, вследствие декомпенсации углеводного обмена у пациен- тов с СД развиваются нейропатия и васкулопатия, приводящие, прежде всего к функциональным нарушениям, с другой ? СД является фоном для развития инфекционно-воспалительных за- болеваний мочеполовой системы. К типичным нейрогенным и ва- скулогеным осложнениям СД относятся эректильная дисфунк ция (ЭД), нарушения эякуляции и диабетическая цистопатия. К ин- фекционно-воспалительным заболеваниям, развивающимся на фоне СД, относятся пиелонефрит, цистит и баланопостит.

About the Authors

Roman Viktorovich Rozhivanov
Endocrinology Research Centre, Moscow


A N Akimova
Endocrinology Research Centre, Moscow


S A Dubsky
Endocrinology Research Centre, Moscow


Dmitriy Gennad'evich Kurbatov
Endocrinology Research Centre, Moscow


Ivan Ivanovich Dedov
Endocrinology Research Centre, Moscow


References

1. Ayta I.A., McKinlay J.B., Krane R.J. The likely worldwide increase in erectile dysfunction between 1995 and 2025 and some possible policy consequences. Br J Urol Int 1999; 84: 50-56.

2. Craig A. One in Ten. London: Impotence Association; 1998.

3. Vinik A., Richardson D. Erectile dysfunction in diabetes. Diabetes Rev 1998; 6(1):16-33.

4. Brunner G.A., Pieber T.R., Schattenberg S., et al. Erectile dysfunction in patients with type I diabetes mellitus. Wien Med Wochenschr 1995; 145(21): 584-586.

5. El-Rufaie O.E., Bener A., Abuzeid M.S., Ali T.A. Sexual dysfunction among type II diabetic men: a controlled study. J Psychosom Res 1997; 43(6): 605-612.

6. Eardley I., Gale E. Diabetic impotence. In: Kirby R.S., Carson C.C., Webster G.D., eds. Impotence Diagnosis and Management of Erectile Dysfunction. Butterworth-Heinemann; 2001.

7. Bancroft J., Gutierrez P. Erectile dysfunction in men with and -without diabetes mellitus: a comparative study. Diabet Med 1996; 13(1): 84-89.

8. Роживанов Р. В. Эректильная дисфункция у больных сахарным диабетом: скрининг, структура, прогностическое значение. Дисс. к.м.н. - Москва; 2005: 133.

9. Bacon C.G., Hu F.B., Giovannucci E. Association of Type and Duration of Diabetes With Erectile Dysfunction in a Large Cohort of Men. Diabetes Care 2002; 25(8): 1417.

10. Под ред. Коган М.И. Нарушения половой функции у мужчин при сахарном диабете. Москва; 2005: 224.

11. Fedele D., Bortolotti A., Coscelli C., et al. Erectile dysfunction in type 1 and type 2 diabetics in Italy. Int J Epidemiol 2000; 29: 524-531.

12. Jonler M., Moon T., Brannan W., Stone N.N., Heisey D., Bruskewitz R.C. The effect of age, ethnicity and geographical location on impotence and quality of life. Br J Uro 1995; 75: 651-655.

13. De la Vega J. S., Amaya Gutierrez J., Alonso Flores J.J., et al. Erectile dysfunction in those under 40. Etiological and contributing factors. Arch Esp Urol 2003; 56(2): 161-164.

14. Whitehead E.D., Klyde B.J. Diabetes-related impotence in the elderly. Clin Geriatr Med 1990; 6: 771-795.

15. Sullivan M.E., Thompson C.S., Dashwood M.R., Khan M.A., Jeremy J.Y., Morgan R.J. et al. Nitric oxide and penile erection: is erectile dysfunction another manifestation of vascular diseae? Cardiovasc Res 1999; 43(3): 58-665.

16. Siu S.C., Lo S.K., Wong K.W., et al. Prevalence of and risk factors for erectile dysfunction in Hong Kong diabetic patients. Diabet Med 2001; 18(9): 732-738.

17. Romeo J.H., Seftel A.D., Madhun Z.T., Aron D.C. Sexual function in men with diabetes type 2: association with glycemic control. J Urol 2000; 163(3): 788-791.

18. Naya Y., Mizutani Y., Ochiai A., et al. Preliminary report of association of chronic diseases and erectile dysfunction in middle-aged men in Japan. Urology 2003; 62(3): 532-536.

19. Shiri R., Koskimaki J., Hakama M., et al. Effect of chronic diseases on incidence of erectile dysfunction. Urology 2003; 62(6): 1097-1102.

20. Klein R., Klein B.E, Lee K.E, et al. Prevalence of selfreported erectile dysfunction in people with long-term IDDM. Diabetes Care 1996; 19(2): 135-141.

21. Tesfaye S., Stevens L.K., Stephenson J.M., et al. Prevalence of diabetic peripheral neuropathy and its relation to glycaemic control and potential risk factors: the EURODIAB IDDM Complications Study. Diabetologia 1996; 39: 1377-1384.

22. Фомкин Р.Г. Патогенез, диагностика и лечение эректильной дисфункции при сахарном диабете. Дисс. к.м.н. - Ростов-на-Дону 2001; 197с.

23. Hakim L.S., Goldstein I. Diabetic sexual dysfunction. Endocrinol Metab Clin.North Am 1996; 25: 379-400.

24. Harati Y. Diabetes and the nervous system. Endocrinology and Metabolism Clinics; Chronic complications of diabetes 1996; 25(2): 552-607.

25. O'Hare J.A., Abuaisha F., Geoghegan M. Prevalence and forms of neuropathic morbidity in 800 diabetics. Ir J Med Sci 1994; 163: 132-135.

26. Vardi Y., Sprecher E., Kanter Y., et al. Polyneuropathy in impotence. Int J Impot Res 1996; 8(2): 65-68.

27. Vinik A.I., Maser R.E., Mitchell B.D., Freeman R. Diabetic autonomic neuropathy. Diabetes Care 2003; 26(5): 1553-1579.

28. Ziegler D. Clinical aspects, diagnosis and therapy of diabetic neuropathy. Ther Umsch 1996; 53(12): 948-957.

29. Rozhivanov R.V., Kalinchenko S.Yu. Neurological criteria of neurogenic erictile dysfunction diagnostics in patients with diabetes. Abstract of 3rd- European Congress of Andrology Munster, Germany, 11-14 September 2004. - P.193

30. Benvenuti F., Boncinelli L., Vignoli G.C. Male sexual impotence in diabetes mellitus: vasculogenic versus neurogenic factors. Neurourol. Urodyn 1993;12: 145-151.

31. Kloner R.A., Speakman M. Erectile dysfunction and atherosclerosis. Curr Atheroscler Rep 2002; 4(5): 397-401.

32. Nisen И.О., Alfthan O.S., Lindstrom B.L, et al. Cardiovascular reflexes in the neurological evaluation of impotence. Br J Urol 1993; 71(2): 199-203.

33. Kayigil 0., Atahan 0., Metin A. Multifactorial evaluation of diabetic erectile dysfunction. Int Urol Nephrol 1996; 28(5): 717-721.

34. Walczak M.K., Lokhandwala N., Hodge M.B., Guay A.T. Prevalence of cardiovascular risk factors in erectile dysfunction. J Gend Specif Med 2002; 5(6): 19-24.

35. Metro M.J., Broderick G.A. Diabetes and vascular impotence: does insulin dependence increase the relative severity? Int J Impot Res 1999; 11(2): 87-89.

36. Зубарев А.Р., Митькова М.Д., Корякин М.В., Митьков В.В. Ультразвуковая диагностика заболеваний наружных половых органов у мужчин. Москва; 1999: 96 с.

37. Кротовский Г.С., Зудин А.М. Виагра-пять лет успеха. Москва; 2003: 191 с.

38. Jevtich M.J., Kass M., Khawand N. Changes in the corpora cavernosa of impotent diabetics: comparing histological with clinical findings. J d'Urol (Paris) 1985; 91: 281-285.

39. Seftel A.D., Vaziri N.D., Ni Z., et al. Advanced glycation end products in human penis: elevation in diabetic tissue, site of deposition, and possible effect through iNOS or eNOS. Urology 1997; 50(6): 1016-1026.

40. Hayashi К., Takamizawa К., Nakamura Т., et al. Effects of elastase on the stiffness and elastic properties of arterial walls in cholesterol-fed rabbits. Atherosclerosis 1987; 66: 259-267.

41. Bar-Moshe O., Vandendris M. Treatment of impotence due to perineal venous leakage by ligation of crura penis. J Urol 1988; 139: 1217-1219.

42. El-Sakka A.I. Penile axial rigidity and Doppler ultrasonography parameters in patients with erectile dysfunction: association with type 2 diabetes. Urology 2003; 62(3): 525-531.

43. Dhindsa S., Prabhakar S., Sethi M., Yopadhyay A.B., Chaudhuri A., Dandona P. Frequent Occurrence of Hypogonadotropic Hypogonadism in Type 2 Diabetes. The J of Clinical Endocrinology and Metabolism 2004; 89(11): 5462-5468.

44. Rossi P., Menchini Fabris F., Fiorini I., et al. Comparison between plasma concentrations of testosterone, nitric oxide and endothelin 1-2 in penile and brachial venous blood: preliminary results in men with psychogenic impotence. Biomed. Pharmacother 1998; 52(7-8): 308-310.

45. Schirar A., Chang С., Rousseau J.P. Localization of androgen receptor in nitric oxide synthase- and vasoactive intestinal peptide-containing neurons of the major pelvic ganglion innervating the rat penis. J Neuroendocrinol 1997; 9(2): 141-150.

46. Schiavi R.C., White D., Mandeli J., Schreiner-Engel P. Hormones and nocturnal penile tumescence in healthy aging men. Arch Sex Behav 1993; 22(3): 207-215.

47. Alexopoulou O., Jamart J., Maiter D., et al. Erectile dysfunction and lower androgenicity in type 1 diabetic patients. Diabetes Metab 2001; 27(3): 329-336.

48. Baskin H.J. Endocrinologic evaluation of impotence. South Med J 1989; 82(4): 446-449.

49. Cunningham M.J., Clifton D.K., Steiner R.A. Leptin's actions on the reproductive axis: perspectives and mechanisms. Biol Reprod 1999; 60: 216-222.

50. Дедов И.И., Калинченко С.Ю. Возрастной андрогенный дефицит у мужчин; 2006 - 240 с.

51. Ермачек Е. А. Влияние пероральной сахароснижающей терапии на андрогенный статус и состояние половой функции у мужчин с сахарным диабетом типа 2. Дисс. к.м.н. - Москва, 2007. - 79 с.

52. Veves A., Webster L., Chen T.F., et al. Aetiopathogenesis and management of impotence in diabetic males: four years experience from a combined clinic. Diabet Med 1995; 12(1): 77-82.

53. De Berardis G., Franciosi M., Belfiglio M., et al. The Quality of Care and Outcomes in Type 2 Diabetes (QuED) Study Group: Erectile dysfunction and quality of life in type 2 diabetic patients. Diabetes Care 2002; 25: 284-291.

54. Rubin R.R., Peyrot M. Persistence of depressive symptoms in diabetic adults. Diabetes Care 1999; 22(3): 448-452.

55. Carton J.A., J.A. Maradona, F.J. Nuno, R. Fernandez-Alvarez, F. Perez- Gonzalez and V. Asensi, Diabetes mellitus and bacteraemia: a comparative study between diabetic and non-diabetic patients. Eur J Med 1992; 1: 281-287

56. Rendell M.S., Rajfer J., Wicker P.A., Smith M. D. For the Sildenafil Diabetes Study Group: Sildenafil for treatment of erectile dysfunction in men with diabetes: a randomized controlled trial. JAMA 1999; 281: 421-426.

57. Willke R.J., Yen W., Parkerson G.R., Linet O.I., Erder M.H., Glick H.A. Quality of life effects of alprostadil therapy for erectile dysfunction: results of a trial in Europe and South Africa. Int J Impot Res 1998; 10: 239-246.

58. Enzlin P., Chantal M., Van Den Bruel A., et al. Prevalence and Predictors of Sexual Dysfunction in Patients With Type 1 Diabetes. Diabetes Care 2003; 26: 409-414.

59. Кратохвил С. Психотерапия семейно-сексуальных дисгармоний. Москва; 1991.

60. Richardson D., A. Nalabanda, D. Goldmeier. Retarded ejaculation - a review. Int J STD AIDS 2006; 17: 143-150.

61. Nicolosi A., D. B. Glasser, G. Brock, E. Laumann, C. Gingell Diabetes and sexual function in older adults: results of an international survey. The British Journal of Diabetes & Vascular Disease 2002; 2: 336-339.

62. Takahashi Y and Y Iwamoto Sexual dysfunction in diabetes mellitus. Nippon Rinsho 1997; 55(11): 2991-5.

63. Chartier-Kastler E., Averous M., Barrou B., Lopez C., Moscovici J., Roman F, Delmas V. Diabetes and urination disorders. Prog Urol 2000; 10(1): 14-23.

64. Hill S. R., Fayyad A. M., Jones G. R. Diabetes mellitus and female lower urinary tract symptoms. Neurourol Urodyn 2007.

65. Hunter K. F., Moore K. N. Diabetes-associated bladder dysfunction in the older adult (CE). Geriatr Nurs 2003; 24(3): 138-45.

66. Hampel C., Gillitzer R., Pahernik S., Melchior S., Thџroff J. W. Diabetes mellitus and bladder function. What should be considered? Urologe A 2003; 42(12): 1556-63.

67. Yang Z., Dolber P. C., Fraser M. O. Diabetic urethropathy compounds the effects of diabetic cystopathy. J Urol 2007; 178(5): 2213-19.

68. Kebapc N., Yenilmez A., Efe B., Entok E., Demirustu C. Bladder dysfunction in type 2 diabetic patients. Neurourol Urodynam 2007; 26: 814-819.

69. Esteghamati A., Rashidi A., Nikfallah A., Yousefizadeh A. The association between urodynamic findings and microvascular complications in patients with long-term type 2 diabetes but without voiding symptoms. Diabetes Res Clin Pract 2007; 78(1): 42-50.

70. Michel M. C., Mehlburger L., Schumacher H., Bressel H. U., Goepel M. Effect of diabetes on lower urinary tract symptoms in patients with benign prostatic hyperplasia. J Urol 2000; 163 :1725-1729.

71. Aruna V. Sarma. Associations Between Diabetes and Clinical Markers of Benign Prostatic Hyperplasia Among Community-Dwelling Black and White Men. Diabetes Care 2008; 31: 476-482.

72. Dib P.T., Trigo-Rocha F., Gomes C. M., Srougi M. Urodynamic evaluation in diabetic patients with prostate enlargement and lower urinary tract symptoms. Urol Int 2008; 80(4): 378-82.

73. Parsons JK, Carter HB, Partin AW, Windham BG, Metter EJ, Ferrucci L, Landis P, Platz EA. Metabolic factors associated with benign prostatic hyperplasia. J Clin Endocrinol Metab 2006; 91(7): 2562-8

74. Hammarsten J, Hљgstedt B. Clinical, anthropometric, metabolic and insulin profile of men with fast annual growth rates of benign prostatic hyperplasia. Blood Press 1999; 8(1): 29-36

75. Дедов И.И., Шестакова М.В. Диабетическая нефропатия. Москва; 2000 - 241 с.

76. Geerlings S.E., R.P. Stolk, M.J. Camps, P.M. Netten, J.B.L. Hoekstra and K.P. Bouter et al., Asymptomatic bacteriuria may be considered a complication in women with diabetes. Diabetes Mellitus Women Asymptomatic Bacteriuria Utrecht Study Group.00 Diabetes Care 2000; 23: 744-749

77. Joshi N., G.M. Caputo, M.R. Weitekamp and A.W. Karchmer, Infections in patients with diabetes mellitus. N Engl J Med 1999; 341: 1906-1912

78. Ludwig E. Urinary tract infections in diabetes mellitus. Orv Hetil 2008; 149(13): 597-600.

79. Geerlings S.E., E.C. Brouwer, K.C. Van Kessel, W. Gaastra, R.P. Stolk and A.I. Hoepelman, Cytokine secretion is impaired in women with diabetes mellitus. Eur J Clin Invest 2000; 30: 995-1001

80. Geerlings S.E., R. Meiland, E.C. van Lith, E.C. Brouwer, W. Gaastra and A.I. Hoepelman, Adherence of type 1-fimbriated Escherichia coli to uroepithelial cells: more in diabetic women than in control subjects. Diabetes Care 2002; 25: 1405-1409.

81. Geerlings S. E. Urinary tract infections in patients with diabetes mellitus: epidemiology, pathogenesis and treatment. Int J Antimicrob Agents 2008; 31(Suppl 1): 54-7

82. Mulvey M. A., J.D. Schilling, J.J. Martinez et al., Bad bugs and beleaguered bladders: interplay between uropathogenic Escherichia coli and innate host defenses. Proc Natl Acad Sci USA 2000; 97(16): 8829-8835.

83. Geerlings S.E., R.P. Stolk, M.J.L. Camps et al. Risk factors for symptomatic urinary tract infection in women with diabetes mellitus. Diabetes Care 2000; 23(12): 1737-1741.

84. Hooton T.M., D. Scholes, A.E. Stapleton et al. A prospective study of asymptomatic bacteriuria in sexually active young women. N Engl J Med 2000; 343(14): 992-997

85. Забиров К.И., Деревянко И.И., Марчук Н.В. Современные аспекты проблемы баланопостита. Consilium Medicum 2004; 6(3).

86. Hoepelman A. I., Meiland R, Geerlings SE. Pathogenesis and management of bacterial urinary tract infections in adult patients with diabetes mellitus. Int J Antimicrob Agents 2003; 22 (Suppl 2): 35-43.

87. Dutta P., Bhansali A, Singh SK, Gupta KL, Bhat MH, Masoodi SR, Kumar Y. Presentation and outcome of emphysematous renal tract disease in patients with diabetes mellitus. Urol Int 2007; 78(1): 13-22

88. Guillausseau P. J., Farah R, Laloi-Michelin M, Tielmans A, Rymer R, Warnet A. Urinary tract infections and diabetes mellitus. Rev Prat 2003; 53(16): 1790-6.


Review

For citations:


Rozhivanov R.V., Akimova A.N., Dubsky S.A., Kurbatov D.G., Dedov I.I. Specific features of urogenital disorders in patents with diabetes mellitus. Diabetes mellitus. 2009;12(2):40-45. (In Russ.) https://doi.org/10.14341/2072-0351-5396

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ISSN 2072-0351 (Print)
ISSN 2072-0378 (Online)