Severe neuropathy in a patient with ischemic heart disease and type 2 diabetes
https://doi.org/10.14341/DM8052
Abstract
The article describes a variety of severe clinical manifestations of diabetic autonomic neuropathy in patients with type 2 diabetes mellitus and coronary heart disease. The peculiarity of this case is the simultaneous onset of autonomic neuropathy and lesions of the cardiovascular system, complications of untreated diabetes, without acute decompensation in carbohydrate metabolism.
About the Authors
Victor Yur'evich Kalashnikov
Endocrinology Research Centre
Russian Federation
MD, PhD, Professor, correspondence fellow of the Russian Academy of Sciences
Competing Interests: no conflict of interest
Russian Federation
MD, PhD, Professor, correspondence fellow of the Russian Academy of Sciences
Competing Interests: no conflict of interest
Olga Michailovna Smirnova
Endocrinology Research Centre;
I.M.Sechenov First Moscow State Medical University
Russian Federation
MD, PhD, Professor
Competing Interests: no conflict of interest
Russian Federation
MD, PhD, Professor
Competing Interests: no conflict of interest
Konstantin Vladimirovich Melkozerov
Endocrinology Research Centre
Russian Federation
MD, PhD
Competing Interests: no conflict of interest
Russian Federation
MD, PhD
Competing Interests: no conflict of interest
Diana Dzhemalovna Beshlieva
Endocrinology Research Centre
Russian Federation
MD
Competing Interests: no conflict of interest
Russian Federation
MD
Competing Interests: no conflict of interest
Anastasiya Andreevna Tovarnova
Endocrinology research center
Russian Federation
MD
Competing Interests: no conflict of interest
Russian Federation
MD
Competing Interests: no conflict of interest
References
1. Дедов И.И., Шестакова М.В., Галстян Г.Р., и др. Алгоритмы специализированной медицинской помощи больным сахарным диабетом. Под редакцией И.И. Дедова, М.В. Шестаковой (7-й выпуск) // Сахарный диабет. – 2015. – Т. 18. – №1S – C. 1-112. [Dedov II, Shestakova MV, Galstyan GR, et al. Standards of specialized diabetes care. Edited by Dedov I.I., Shestakova M.V. (7th edition). Diabetes mellitus. 2015;18(1S):1-112. (in Russ)] doi: 10.14341/DM20151S1-112
2. Сахарный диабет. Острые и хронические осложнения. / Под редакцией Дедова И.И., Шестаковой М.В. – М.: Медицинское информационное агентство; 2011. [Diabetes Mellitus. Acute and chronic complications. Edited by Dedov II, Shestakova MV. Moscow: Medical news Agency; 2011. (in Russ)]
3. Maser RE, Mitchell BD, Vinik AI, Freeman R. The Association Between Cardiovascular Autonomic Neuropathy and Mortality in Individuals With Diabetes. A meta-analysis. Diabetes Care. 2003;26(6):1895-1901. doi: 10.2337/diacare.26.6.1895
4. Kempler P. Review: Autonomic neuropathy: a marker of cardiovascular risk. Br. J. Diabetes Vasc. Dis. 2003;3(2):84-90.
5. Gazzaruso C, Giordanetti S, De Amici E, et al. Relationship between erectile dysfunction and silent myocardial ischemia in apparently uncomplicated type 2 diabetic patients. Circulation. 2004;110(1):22-26. doi: 10.1161/01.cir.0000133278.81226.c9
6. Vinik AI, Maser RE, Mitchell BD, Freeman R. Diabetic Autonomic Neuropathy. Diabetes Care. 2003;26(5):1553-1579. doi: 10.2337/diacare.26.5.1553
7. Vinik A.I., Erbas T. Recognizing and treating diabetic autonomicneuropathy. Cleve Clin J Med. 2001;68(11):928-30, 932, 934-44.
8. Черникова Н.А. Диабетическая автономная нейропатия: проблемы и решения. // Эффективная фармакотерапия. Эндокринология. – 2012. – №5 – С.62-68. [Chernikova NA. Diabeticheskaya avtonomnaya neyropatiya: problemy i resheniya. Effektivnaya farmakoterapiya. Endokrinologiya. 2012;(5):62-68. (in Russ)]
9. Бешлиева Д.Д., Калашников В.Ю., Смирнова О.М. Кардиоваскулярная автономная невропатия у больных сахарным диабетом 2-го типа и ишемической болезнью сердца: диагностика и оценка тяжести. // Терапевтический архив. – 2015. – Т. 87. – №10 – С.11-18. [Beshlieva DD, Kalashnikov VYu, Smirnova OM. Cardiovascular autonomic neuropathy in patients with type 2 diabetes mellitus and coronary artery disease: Diagnosis and severity assessment. Ter. Arkh. 2015;87(10): 11-18 (in Russ)] doi: 10.17116/terarkh2015871011-18
10. Spallone V, Ziegler D, Freeman R, et al. Cardiovascular autonomic neuropathy in diabetes: clinical impact, assessment, diagnosis, and management. Diabetes Metab Res Rev. 2011;27(7):639-653. doi: 10.1002/dmrr.1239
11. Дедов И.И., Бондаренко И.З., Ахматова Ф.Д., и др. Кардиальная автономная нейропатия в диагностике ишемической болезни сердца у больных сахарным диабетом типа 1 // Сахарный диабет. – 2003. – Т. 6. – №4 – C. 2-7. [Dedov II, Bondarenko IZ, Akhmatova FD, et al. Kardial’naya avtonomnaya neyropatiya v diagnostike ishemicheskoy bolezni serdtsa u bol’nykh sakharnym diabetom tipa 1. Diabetes mellitus. 2003;6(4):2-7. (in Russ)] doi: 10.14341/2072-0351-5836
12. Task Force of the European Society of Cardiology and the North American Society of Pacing and Electrophysiology: Heart Rate Variability. Standards of Measurement, Physiological Interpretation, and Clinical Use. Circulation. 1996;93:1043-1065. doi: 10.1161/01.cir.93.5.1043
13. Ziegler D, Piolot R. Evaluation of statistical, geometric, frequence domain, and nonlinear measures of 244-hour heart rate variability in diabetic patients with various degrees of cardiovascular autonomic neuropathy. Clin Auton Res. 1998;8:282-283.
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For citations:
Kalashnikov V.Yu., Smirnova O.M., Melkozerov K.V., Beshlieva D.D., Tovarnova A.A. Severe neuropathy in a patient with ischemic heart disease and type 2 diabetes. Diabetes mellitus. 2016;19(5):421-427. (In Russ.) https://doi.org/10.14341/DM8052
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