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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">diaendo</journal-id><journal-title-group><journal-title xml:lang="ru">Сахарный диабет</journal-title><trans-title-group xml:lang="en"><trans-title>Diabetes mellitus</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2072-0351</issn><issn pub-type="epub">2072-0378</issn><publisher><publisher-name>Endocrinology research centre</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14341/DM2015269-78</article-id><article-id custom-type="elpub" pub-id-type="custom">diaendo-6990</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Хроническая болезнь почек</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Chronic Kidney Disease</subject></subj-group></article-categories><title-group><article-title>Влияние сочетанной трансплантации почки и поджелудочной железы на динамику поздних осложнений у больных сахарным диабетом 1 типа</article-title><trans-title-group xml:lang="en"><trans-title>Late Diabetic Complications in Patients with Type 1 Diabetes who Received Simultaneous Pancreas-Kidney Transplantation</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Глазунова</surname><given-names>Александра Михайловна</given-names></name><name name-style="western" xml:lang="en"><surname>Glazunova</surname><given-names>Alexandra Michailovna</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"><p>MD, Research fellow, Department of Diabetic Nephropathy and Haemodialysis</p></bio><email xlink:type="simple">ivetta_86@inbox.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Арутюнова</surname><given-names>Маргарита Станиславовна</given-names></name><name name-style="western" xml:lang="en"><surname>Arutyunova</surname><given-names>Margarita Stanislavovna</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"><p>MD, Research fellow, Department of Diabetic Nephropathy and Haemodialysis</p></bio><email xlink:type="simple">rituzik-uezd@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тарасов</surname><given-names>Евгений Владимирович</given-names></name><name name-style="western" xml:lang="en"><surname>Tarasov</surname><given-names>Evgeny Vladimirovich</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"><p>MD, Endocrinologist, Department of Diabetic Nephropathy and Haemodialysis</p></bio><email xlink:type="simple">tarasov-ev@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шамхалова</surname><given-names>Минара Шамхаловна</given-names></name><name name-style="western" xml:lang="en"><surname>Shamhalova</surname><given-names>Minara Shamkhalovna</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"><p>MD, PhD, Head of Department of Diabetic Nephropathy and Haemodialysis</p></bio><email xlink:type="simple">shamkhalova@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шестакова</surname><given-names>Марина Владимировна</given-names></name><name name-style="western" xml:lang="en"><surname>Shestakova</surname><given-names>Marina Vladimirovna</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"><p>MD, PhD, Professor, Corresponding member of RAS, Director of Institute of Diabetes</p></bio><email xlink:type="simple">nephro@endocrincentr.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мойсюк</surname><given-names>Ян Геннадьевич</given-names></name><name name-style="western" xml:lang="en"><surname>Moysyuk</surname><given-names>Yan Gennad'evich</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"><p>MD, PhD, Professor, Head of Department of Liver and Kidney Transplantation</p></bio><email xlink:type="simple">moysyuktrans@list.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Пинчук</surname><given-names>Алексей Валерьевич</given-names></name><name name-style="western" xml:lang="en"><surname>Pinchuk</surname><given-names>Aleksey Valer'evich</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"><p>MD, Head of Scientific Department of Kidney and Pancreas Transplantation</p></bio><email xlink:type="simple">AVPIN@rambler.ru</email><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дмитриев</surname><given-names>Илья Викторович</given-names></name><name name-style="western" xml:lang="en"><surname>Dmitriev</surname><given-names>Ilya Viktorovich</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"><p>MD, Head of Clinical Department of Kidney and Pancreas Transplantation</p></bio><email xlink:type="simple">ildmi@mail.ru</email><xref ref-type="aff" rid="aff-5"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Арзуманов</surname><given-names>Сергей Викторович</given-names></name><name name-style="western" xml:lang="en"><surname>Arzumanov</surname><given-names>Sergei Viktorovich</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"><p>MD, PhD, Head of Department of Transplantation and Renal Replacement Therapy</p></bio><email xlink:type="simple">kidneytranspl@gmail.com</email><xref ref-type="aff" rid="aff-6"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ Эндокринологический научный центр, Москва</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Endocrinology Research Centre, Moscow</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБУ Эндокринологический научный центр, Москва; ГБОУ ВПО Первый МГМУ им. И.М.Сеченова, Москва</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Endocrinology Research Centre, Moscow</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ФГБУ Федеральный научный центр трансплантологии и искусственных органов им. академика В.И. Шумакова, Москва</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal Research Center of Transplantology and Artificial Organs named after V.I. Shumakov, Moscow</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>Научно-исследовательский институт скорой помощи им. Н.В. Склифосовского, Москва</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Scientific and Research Institute for Emergency Care named.after N.V. Sklifosovsky, Moscow</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-5"><aff xml:lang="ru"><institution>Научно-исследовательский институт скорой помощи имени Н.В. Склифосовского, Москва</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Scientific and Research Institute for Emergency Care named.after N.V. Sklifosovsky, Moscow</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-6"><aff xml:lang="ru"><institution>НИИ урологии им. Н.А. Лопаткина. ФГБУ ФМИЦ им. П.А. Герцена, Москва</institution><country>Россия</country></aff><aff xml:lang="en"><institution>“NII Urologii” named after N.A. Lopatkin, Hertsen Federal Medical Research Centre, Moscow</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2015</year></pub-date><pub-date pub-type="epub"><day>04</day><month>03</month><year>2015</year></pub-date><volume>18</volume><issue>2</issue><fpage>69</fpage><lpage>78</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Глазунова А.М., Арутюнова М.С., Тарасов Е.В., Шамхалова М.Ш., Шестакова М.В., Мойсюк Я.Г., Пинчук А.В., Дмитриев И.В., Арзуманов С.В., 2015</copyright-statement><copyright-year>2015</copyright-year><copyright-holder xml:lang="ru">Глазунова А.М., Арутюнова М.С., Тарасов Е.В., Шамхалова М.Ш., Шестакова М.В., Мойсюк Я.Г., Пинчук А.В., Дмитриев И.В., Арзуманов С.В.</copyright-holder><copyright-holder xml:lang="en">Glazunova A.M., Arutyunova M.S., Tarasov E.V., Shamhalova M.S., Shestakova M.V., Moysyuk Y.G., Pinchuk A.V., Dmitriev I.V., Arzumanov S.V.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.dia-endojournals.ru/jour/article/view/6990">https://www.dia-endojournals.ru/jour/article/view/6990</self-uri><abstract/><trans-abstract xml:lang="en"/><kwd-group xml:lang="ru"><kwd>сахарный диабет 1 типа</kwd><kwd>диабетическая нефропатия</kwd><kwd>сочетанная трансплантация поджелудочной железы и почки</kwd><kwd>динамика осложнений сахарного диабета</kwd></kwd-group><kwd-group xml:lang="en"><kwd>diabetes mellitus type 1</kwd><kwd>diabetic nephropathy</kwd><kwd>simultaneous pancreas-kidney transplantation</kwd><kwd>complications of diabetes</kwd></kwd-group></article-meta></front><body><sec><title>Актуальность</title></sec><sec><title>Цель</title></sec><sec><title>Материалы и методы</title></sec><sec><title>Результаты и их обсуждение</title><table-wrap id="table-1"><table><tbody><tr><td>Параметры</td><td>Группа СТПиПЖ (n=16)</td></tr><tr><td>ИМТ, кг/м2</td><td>19,6 [17,9; 22,6]</td></tr><tr><td>СКФ, мл/мин/1,73м2</td><td>76 [68; 90]</td></tr><tr><td>Альбуминурия, мг/л</td><td>5,45[2,7; 6,5]</td></tr><tr><td>HbA1c, %</td><td>5,7 [5,5; 5,9]</td></tr><tr><td>САД, мм рт. ст.</td><td>110 [105; 122]</td></tr><tr><td>ДАД, мм рт. ст.</td><td>70 [64; 80]</td></tr><tr><td>Холестерин общий, ммоль/л</td><td>4,9 [3,95; 5,5]</td></tr><tr><td>ЛПНП, ммоль/л</td><td>3,25 [2,3; 3,5]</td></tr><tr><td>ЛПВП, ммоль/л</td><td>1,48 [1,37; 1,85]</td></tr><tr><td>Триглицериды, ммоль/л</td><td>1,0 [0,74; 1,18]</td></tr><tr><td>ФВ левого желудочка, %</td><td>62 [60; 63,3]</td></tr><tr><td>ИММЛЖ, г/м2</td><td>114,1 [102,5; 141]</td></tr><tr><td>Стентирование СНК, n (%)</td><td>1 (6,25)</td></tr><tr><td>Диабетическая ретинопатия(ДР 3 ст, n (%))</td><td>16 (100)</td></tr></tbody></table></table-wrap></sec><sec><title>Информация о финансировании и конфликте интересов</title></sec></body><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Дедов И.И. 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