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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">diaendo</journal-id><journal-title-group><journal-title xml:lang="ru">Сахарный диабет</journal-title><trans-title-group xml:lang="en"><trans-title>Diabetes mellitus</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2072-0351</issn><issn pub-type="epub">2072-0378</issn><publisher><publisher-name>Endocrinology research centre</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14341/DM9292</article-id><article-id custom-type="elpub" pub-id-type="custom">diaendo-9292</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Обзоры</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Review</subject></subj-group></article-categories><title-group><article-title>Возможности метаболической хирургии в лечении сахарного диабета 2 типа у больных с алиментарным ожирением 1 степени</article-title><trans-title-group xml:lang="en"><trans-title>Possibilities of metabolic surgery for the treatment of type 2 diabetes mellitus in patients with grade 1 alimentary obesity</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1851-0941</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Салухов</surname><given-names>Владимир Владимирович</given-names></name><name name-style="western" xml:lang="en"><surname>Salukhov</surname><given-names>Vladimir V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>доктор медицинских наук, начальник 1 кафедры  и клиники (терапии усовершенствования врачей)</p></bio><bio xml:lang="en"><p>Head of the 1st (Clinic of therapy for postgraduate course)</p></bio><email xlink:type="simple">vlasaluk@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7406-753X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ильинский</surname><given-names>Никита Сергеевич</given-names></name><name name-style="western" xml:lang="en"><surname>Ilinskii</surname><given-names>Nikita S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Клинический ординатор по терапии при 1 кафедре (терапии усовершенствования врачей)</p></bio><bio xml:lang="en"><p>resedent in therapy</p></bio><email xlink:type="simple">nika_il2@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0064-0465</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Васильев</surname><given-names>Евгений Владимирович</given-names></name><name name-style="western" xml:lang="en"><surname>Vasil'ev</surname><given-names>Evgenii V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>врач- эндокринолог</p></bio><bio xml:lang="en"><p>endocrinologist</p></bio><email xlink:type="simple">vasilievev@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5402-3975</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сардинов</surname><given-names>Руслан Тальгатович</given-names></name><name name-style="western" xml:lang="en"><surname>Sardinov</surname><given-names>Ruslan T.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кандидат медицинских наук, преподаватель 1 кафедры (терапии усовершенствования врачей)</p></bio><bio xml:lang="en"><p>Associate professor </p></bio><email xlink:type="simple">sardinovr@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5318-2619</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гладышев</surname><given-names>Дмитрий Владимирович</given-names></name><name name-style="western" xml:lang="en"><surname>Gladyshev</surname><given-names>Dmitrii V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кандидат медицинских наук, главный специалист по хирургии </p></bio><bio xml:lang="en"><p>Head in surgery</p></bio><email xlink:type="simple">gladyshevd@gmail.com</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>&lt;p&gt;ФГБВОУ ВО &amp;laquo;Военно-медицинская академия имени С.М. Кирова&amp;raquo; Министерства обороны РФ&lt;/p&gt;</institution><country>Россия</country></aff><aff xml:lang="en"><institution>&lt;p&gt;S.M. Kirov Military Medical Academy&lt;/p&gt;</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>&lt;p&gt;ГБУЗ Городская больница №40&lt;/p&gt;</institution><country>Россия</country></aff><aff xml:lang="en"><institution>&lt;p&gt;City Hospital №. 40&lt;/p&gt;</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>27</day><month>03</month><year>2018</year></pub-date><volume>21</volume><issue>1</issue><fpage>15</fpage><lpage>25</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Салухов В.В., Ильинский Н.С., Васильев Е.В., Сардинов Р.Т., Гладышев Д.В., 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Салухов В.В., Ильинский Н.С., Васильев Е.В., Сардинов Р.Т., Гладышев Д.В.</copyright-holder><copyright-holder xml:lang="en">Salukhov V.V., Ilinskii N.S., Vasil'ev E.V., Sardinov R.T., Gladyshev D.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.dia-endojournals.ru/jour/article/view/9292">https://www.dia-endojournals.ru/jour/article/view/9292</self-uri><abstract><p>Многочисленные исследования показали высокую эффективность бариатрической хирургии у пациентов, страдающих ожирением 2–3 степени и сахарным диабетом 2 типа (СД2). В настоящее время хирургическое лечение ожирения является одним из наиболее действенных способов снижения и долгосрочного удержания массы тела и управления СД2. При этом особый интерес вызывает выраженное положительное влияние бариатрических оперативных вмешательств (БОВ) на нарушения углеводного обмена у прооперированных больных, приводящее не только к улучшению течения СД2, но и в значительном числе случаев к его ремиссии. В настоящем обзоре освещены механизмы, связанные с улучшением гликемического контроля у больных ожирением после БОВ, проведен сравнительный анализ различных БОВ на течение СД2, приведены причины постбариатрических гипогликемий, а также предикторы послеоперационного прогноза эффективности бариатрических операций в отношении метаболического контроля у пациентов с ожирением и СД2.</p><p>До недавнего времени основной массив исследований результатов БОВ касался только пациентов с СД2 и ожирением 2–3 степени, однако особое внимание в статье уделено пациентам с индексом массы тела (ИМТ) от 30 до 35 кг/м2. Накопленный опыт демонстрирует убедительную эффективность БОВ во влиянии на течение СД2 у больных ожирением 1 степени, что позволяет серьезно расширить круг пациентов, которым может быть показан тот или иной вариант оперативного лечения. Вместе с тем приводятся данные, касающиеся хирургических и метаболических осложнений БОВ, что определяет необходимость взвешенного подхода к выбору оперативной стратегии лечения.</p></abstract><trans-abstract xml:lang="en"><p>Many studies have demonstrated the high effectiveness of bariatric surgery in patients with grade 2–3 obesity and type 2 diabetes mellitus. Currently, surgery is one of the most effective ways to decrease body mass, to maintain long-term weight loss and to manage type 2 diabetes mellitus. Particular interest has been generated by the strong influence of bariatric surgical interventions on the disruption of carbohydrate metabolism in patients who undergo surgery. This change leads to an improvement in the course of type 2 diabetes mellitus as well as its full remission. This review presents information on the mechanisms that are needed to improve glycaemic control in patients with obesity even after bariatric surgery. This review also contains a comparative analysis of how various surgical interventions influence the course of diabetes, the reasons for postbariatric glycaemia and predictors of the effectiveness of bariatric surgeries in terms of metabolic control in patients with type 2 diabetes mellitus.</p><p>Until recently, the primary focus of the studies by bariatric surgeons was on patients with grade 2–3 obesity and type 2 diabetes mellitus. However, in this review, special attention is given to the patients with a body mass index that ranges from 30 to 35 kg/m. Gained experience of the bariatric surgeons leads to high effectiveness with respect to the influence on the course of diabetes in patients with grade 1 obesity, which allows us to significantly expand the range of patients who should be recommended for this surgery. In addition, some information concerning surgical and metabolic complications of bariatric surgical intervention is provided, which allows us to seriously consider this treatment.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>ожирение</kwd><kwd>сахарный диабет 2 типа</kwd><kwd>бариатрические операции</kwd></kwd-group><kwd-group xml:lang="en"><kwd>obesity</kwd><kwd>type 2 Diabetes Mellitus</kwd><kwd>bariatric surgery</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">International Diabetes Federation. IDF Diabetes Atlas. 8th ed. International Diabetes Federation; 2017.</mixed-citation><mixed-citation xml:lang="en">International Diabetes Federation. IDF Diabetes Atlas. 8th ed. 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