<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">diaendo</journal-id><journal-title-group><journal-title xml:lang="ru">Сахарный диабет</journal-title><trans-title-group xml:lang="en"><trans-title>Diabetes mellitus</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2072-0351</issn><issn pub-type="epub">2072-0378</issn><publisher><publisher-name>Endocrinology research centre</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14341/DM8030</article-id><article-id custom-type="elpub" pub-id-type="custom">diaendo-8030</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Диагностика, контроль, лечение</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Diagnosis, control, treatment</subject></subj-group></article-categories><title-group><article-title>Физическая активность и риск сахарного диабета 2 типа: обзор популяционных исследований</article-title><trans-title-group xml:lang="en"><trans-title>Physical activity and type 2 diabetes mellitus risk: population studies review</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Богатырев</surname><given-names>Сергей Николаевич</given-names></name><name name-style="western" xml:lang="en"><surname>Bogatyrev</surname><given-names>Sergey N.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"/><email xlink:type="simple">sellbor@ngs.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ Научно-исследовательский институт терапии и профилактической медицины</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Institute of Internal and Preventive Medicine</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2016</year></pub-date><pub-date pub-type="epub"><day>02</day><month>12</month><year>2016</year></pub-date><volume>19</volume><issue>6</issue><fpage>486</fpage><lpage>493</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Богатырев С.Н., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Богатырев С.Н.</copyright-holder><copyright-holder xml:lang="en">Bogatyrev S.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.dia-endojournals.ru/jour/article/view/8030">https://www.dia-endojournals.ru/jour/article/view/8030</self-uri><abstract><p>Физическая активность (ФА) является одним из важных компонентов образа жизни человека. Регулярная ФА способствует поддержанию нормального уровня глюкозы в крови и снижает риск возникновения СД, при этом положительно влияя на показатели липидов, АД, сердечно-сосудистыми заболеваниями (ССЗ), смертность и качество жизни. Обзор представляет анализ популяционных исследований, посвященных изучению ФА как фактора риска возникновения СД 2 типа (СД2). Поиск литературных источников проведен по ключевым словам «физическая активность», «сахарный диабет 2 типа», «риск». В обзоре представлены результаты более 40 актуальных оригинальных исследований и метаанализов. Показано положительное протективное влияние различных видов ФА на риск возникновения СД2, а также на снижение риска преждевременной смерти у больных СД2.</p></abstract><trans-abstract xml:lang="en"><p>Physical activity is one of the most important components of a healthy lifestyle. Regular physical activity helps to maintain normal blood glucose levels and reduce the risk of type 2 diabetes mellitus. This review presents population studies investigating physical activity as a factor for type 2 diabetes mellitus risk. A search using the keywords ‘physical activity’, ‘type 2 diabetes mellitus’ and ‘risk’ identified more than 40 relevant original studies and meta-analyses, which are presented in this review. Different types of physical activity have positive protective effects on type 2 diabetes mellitus risk and reduce the risk of death in patients with type 2 diabetes mellitus.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>физическая активность</kwd><kwd>сахарный диабет 2 типа</kwd><kwd>риск</kwd></kwd-group><kwd-group xml:lang="en"><kwd>physical activity</kwd><kwd>type 2 diabetes mellitus</kwd><kwd>risk</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Дедов И.И., Шестакова М.В., Галстян Г.Р. Распространенность сахарного диабета 2 типа у взрослого населения России (исследование NATION) // Сахарный диабет. – 2016. – Т. 19. – №2 – C. 104-112. [Dedov II, Shestakova MV, Galstyan GR. The prevalence of type 2 diabetes mellitus in the adult population of Russia (NATION study). Diabetes mellitus. 2016;19(2):104-112.] doi: 10.14341/DM2004116-17</mixed-citation><mixed-citation xml:lang="en">Дедов И.И., Шестакова М.В., Галстян Г.Р. Распространенность сахарного диабета 2 типа у взрослого населения России (исследование NATION) // Сахарный диабет. – 2016. – Т. 19. – №2 – C. 104-112. [Dedov II, Shestakova MV, Galstyan GR. The prevalence of type 2 diabetes mellitus in the adult population of Russia (NATION study). Diabetes mellitus. 2016;19(2):104-112.] doi: 10.14341/DM2004116-17</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Мустафина С.В., Рымар О.Д., Сазонова О.В., и др. Валидизация финской шкалы риска «FINDRISC» на европеоидной популяции Сибири // Сахарный диабет. – 2016. – Т. 19. – №2 – C. 113-118. [Mustafina SV, Rymar OD, Sazonova OV, Shcherbakova LV, Voevoda MI. Validation of the Finnish diabetes risk score (FINDRISC) for the Caucasian population of Siberia. Diabetes mellitus. 2016;19(2):113-118.] doi: 10.14341/DM200418-10</mixed-citation><mixed-citation xml:lang="en">Мустафина С.В., Рымар О.Д., Сазонова О.В., и др. Валидизация финской шкалы риска «FINDRISC» на европеоидной популяции Сибири // Сахарный диабет. – 2016. – Т. 19. – №2 – C. 113-118. [Mustafina SV, Rymar OD, Sazonova OV, Shcherbakova LV, Voevoda MI. Validation of the Finnish diabetes risk score (FINDRISC) for the Caucasian population of Siberia. Diabetes mellitus. 2016;19(2):113-118.] doi: 10.14341/DM200418-10</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Caspersen CJ. Physical Activity Epidemiology. Exercise and Sport Sciences Reviews. 1989;16:423-474. doi: 10.1249/00003677-198900170-00015</mixed-citation><mixed-citation xml:lang="en">Caspersen CJ. Physical Activity Epidemiology. Exercise and Sport Sciences Reviews. 1989;16:423-474. doi: 10.1249/00003677-198900170-00015</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Colberg SR, Sigal RJ, Fernhall B, et al. Exercise and type 2 diabetes: the American College of Sports Medicine and the American Diabetes Association: joint position statement executive summary. Diabetes Care. 2010;33(12):2692-2696. doi: 10.2337/dc10-1548</mixed-citation><mixed-citation xml:lang="en">Colberg SR, Sigal RJ, Fernhall B, et al. Exercise and type 2 diabetes: the American College of Sports Medicine and the American Diabetes Association: joint position statement executive summary. Diabetes Care. 2010;33(12):2692-2696. doi: 10.2337/dc10-1548</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Duncan GE, Perri MG, Theriaque DW, et al. Exercise Training, Without Weight Loss, Increases Insulin Sensitivity and Postheparin Plasma Lipase Activity in Previously Sedentary Adults. Diabetes Care. 2003;26(3):557-562. doi: 10.2337/diacare.26.3.557</mixed-citation><mixed-citation xml:lang="en">Duncan GE, Perri MG, Theriaque DW, et al. Exercise Training, Without Weight Loss, Increases Insulin Sensitivity and Postheparin Plasma Lipase Activity in Previously Sedentary Adults. Diabetes Care. 2003;26(3):557-562. doi: 10.2337/diacare.26.3.557</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Knowler WC, Barrett-Connor E, Fowler SE, et al. Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N Engl J Med. 2002;346(6):393-403. doi: 10.1056/NEJMoa012512</mixed-citation><mixed-citation xml:lang="en">Knowler WC, Barrett-Connor E, Fowler SE, et al. Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N Engl J Med. 2002;346(6):393-403. doi: 10.1056/NEJMoa012512</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Hamman RF, Wing RR, Edelstein SL, et al. Effect of weight loss with lifestyle intervention on risk of diabetes. Diabetes Care. 2006;29(9):2102-2107. doi: 10.2337/dc06-0560</mixed-citation><mixed-citation xml:lang="en">Hamman RF, Wing RR, Edelstein SL, et al. Effect of weight loss with lifestyle intervention on risk of diabetes. Diabetes Care. 2006;29(9):2102-2107. doi: 10.2337/dc06-0560</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Laaksonen DE, Lindstrom J, Lakka TA, et al. Physical Activity in the Prevention of Type 2 Diabetes: The Finnish Diabetes Prevention Study. Diabetes. 2004;54(1):158-165. doi: 10.2337/diabetes.54.1.158</mixed-citation><mixed-citation xml:lang="en">Laaksonen DE, Lindstrom J, Lakka TA, et al. Physical Activity in the Prevention of Type 2 Diabetes: The Finnish Diabetes Prevention Study. Diabetes. 2004;54(1):158-165. doi: 10.2337/diabetes.54.1.158</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Li G, Zhang P, Wang J, et al. The long-term effect of lifestyle interventions to prevent diabetes in the China Da Qing Diabetes Prevention Study: a 20-year follow-up study. The Lancet. 2008;371(9626):1783-1789. doi: 10.1016/s0140-6736(08)60766-7</mixed-citation><mixed-citation xml:lang="en">Li G, Zhang P, Wang J, et al. The long-term effect of lifestyle interventions to prevent diabetes in the China Da Qing Diabetes Prevention Study: a 20-year follow-up study. The Lancet. 2008;371(9626):1783-1789. doi: 10.1016/s0140-6736(08)60766-7</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Helmrich SP, Ragland DR, Leung RW, Paffenbarger RS, Jr. Physical activity and reduced occurrence of non-insulin-dependent diabetes mellitus. N Engl J Med. 1991;325(3):147-152. doi: 10.1056/NEJM199107183250302</mixed-citation><mixed-citation xml:lang="en">Helmrich SP, Ragland DR, Leung RW, Paffenbarger RS, Jr. Physical activity and reduced occurrence of non-insulin-dependent diabetes mellitus. N Engl J Med. 1991;325(3):147-152. doi: 10.1056/NEJM199107183250302</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Manson JE, Stampfer MJ, Colditz GA, et al. Physical activity and incidence of non-insulin-dependent diabetes mellitus in women. The Lancet. 1991;338(8770):774-778. doi: 10.1016/0140-6736(91)90664-b</mixed-citation><mixed-citation xml:lang="en">Manson JE, Stampfer MJ, Colditz GA, et al. Physical activity and incidence of non-insulin-dependent diabetes mellitus in women. The Lancet. 1991;338(8770):774-778. doi: 10.1016/0140-6736(91)90664-b</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Hu FB, Sigal RJ, Rich-Edwards JW, et al. Walking Compared With Vigorous Physical Activity and Risk of Type 2 Diabetes in Women. Jama. 1999;282(15):1433. doi: 10.1001/jama.282.15.1433</mixed-citation><mixed-citation xml:lang="en">Hu FB, Sigal RJ, Rich-Edwards JW, et al. Walking Compared With Vigorous Physical Activity and Risk of Type 2 Diabetes in Women. Jama. 1999;282(15):1433. doi: 10.1001/jama.282.15.1433</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Sui X, Hooker SP, Lee IM, et al. A prospective study of cardiorespiratory fitness and risk of type 2 diabetes in women. Diabetes Care. 2008;31(3):550-555. doi: 10.2337/dc07-1870</mixed-citation><mixed-citation xml:lang="en">Sui X, Hooker SP, Lee IM, et al. A prospective study of cardiorespiratory fitness and risk of type 2 diabetes in women. Diabetes Care. 2008;31(3):550-555. doi: 10.2337/dc07-1870</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Pan XR, Li GW, Hu YH, et al. Effects of Diet and Exercise in Preventing NIDDM in People With Impaired Glucose Tolerance: The Da Qing IGT and Diabetes Study. Diabetes Care. 1997;20(4):537-544. doi: 10.2337/diacare.20.4.537</mixed-citation><mixed-citation xml:lang="en">Pan XR, Li GW, Hu YH, et al. Effects of Diet and Exercise in Preventing NIDDM in People With Impaired Glucose Tolerance: The Da Qing IGT and Diabetes Study. Diabetes Care. 1997;20(4):537-544. doi: 10.2337/diacare.20.4.537</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Eriksson J, Lindström J, Valle T, et al. Prevention of Type II diabetes in subjects with impaired glucose tolerance: the Diabetes Prevention Study (DPS) in Finland. Diabetologia. 1999;42(7):793-801. doi: 10.1007/s001250051229</mixed-citation><mixed-citation xml:lang="en">Eriksson J, Lindström J, Valle T, et al. Prevention of Type II diabetes in subjects with impaired glucose tolerance: the Diabetes Prevention Study (DPS) in Finland. Diabetologia. 1999;42(7):793-801. doi: 10.1007/s001250051229</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Lindström J, Ilanne-Parikka P, Peltonen M, et al. Sustained reduction in the incidence of type 2 diabetes by lifestyle intervention: follow-up of the Finnish Diabetes Prevention Study. The Lancet. 2006;368(9548):1673-1679. doi: 10.1016/s0140-6736(06)69701-8</mixed-citation><mixed-citation xml:lang="en">Lindström J, Ilanne-Parikka P, Peltonen M, et al. Sustained reduction in the incidence of type 2 diabetes by lifestyle intervention: follow-up of the Finnish Diabetes Prevention Study. The Lancet. 2006;368(9548):1673-1679. doi: 10.1016/s0140-6736(06)69701-8</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Kosaka K, Noda M, Kuzuya T. Prevention of type 2 diabetes by lifestyle intervention: a Japanese trial in IGT males. Diabetes Res Clin Pract. 2005;67(2):152-162. doi: 10.1016/j.diabres.2004.06.010</mixed-citation><mixed-citation xml:lang="en">Kosaka K, Noda M, Kuzuya T. Prevention of type 2 diabetes by lifestyle intervention: a Japanese trial in IGT males. Diabetes Res Clin Pract. 2005;67(2):152-162. doi: 10.1016/j.diabres.2004.06.010</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Tuomilehto J, Lindstrom J, Eriksson JG, et al. Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance. N Engl J Med. 2001;344(18):1343-1350. doi: 10.1056/NEJM200105033441801</mixed-citation><mixed-citation xml:lang="en">Tuomilehto J, Lindstrom J, Eriksson JG, et al. Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance. N Engl J Med. 2001;344(18):1343-1350. doi: 10.1056/NEJM200105033441801</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Lee DC, Sui X, Church TS, et al. Associations of cardiorespiratory fitness and obesity with risks of impaired fasting glucose and type 2 diabetes in men. Diabetes Care. 2009;32(2):257-262. doi: 10.2337/dc08-1377</mixed-citation><mixed-citation xml:lang="en">Lee DC, Sui X, Church TS, et al. Associations of cardiorespiratory fitness and obesity with risks of impaired fasting glucose and type 2 diabetes in men. Diabetes Care. 2009;32(2):257-262. doi: 10.2337/dc08-1377</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Sieverdes JC, Sui X, Lee DC, et al. Physical activity, cardiorespiratory fitness and the incidence of type 2 diabetes in a prospective study of men. Br J Sports Med. 2010;44(4):238-244. doi: 10.1136/bjsm.2009.062117</mixed-citation><mixed-citation xml:lang="en">Sieverdes JC, Sui X, Lee DC, et al. Physical activity, cardiorespiratory fitness and the incidence of type 2 diabetes in a prospective study of men. Br J Sports Med. 2010;44(4):238-244. doi: 10.1136/bjsm.2009.062117</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Carnethon MR, Sternfeld B, Schreiner PJ, et al. Association of 20-year changes in cardiorespiratory fitness with incident type 2 diabetes: the coronary artery risk development in young adults (CARDIA) fitness study. Diabetes Care. 2009;32(7):1284-1288. doi: 10.2337/dc08-1971</mixed-citation><mixed-citation xml:lang="en">Carnethon MR, Sternfeld B, Schreiner PJ, et al. Association of 20-year changes in cardiorespiratory fitness with incident type 2 diabetes: the coronary artery risk development in young adults (CARDIA) fitness study. Diabetes Care. 2009;32(7):1284-1288. doi: 10.2337/dc08-1971</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Gray BJ, Stephens JW, Williams SP, et al. Cardiorespiratory fitness is a stronger indicator of cardiometabolic risk factors and risk prediction than self-reported physical activity levels. Diab Vasc Dis Res. 2015;12(6):428-435. doi: 10.1177/1479164115599907</mixed-citation><mixed-citation xml:lang="en">Gray BJ, Stephens JW, Williams SP, et al. Cardiorespiratory fitness is a stronger indicator of cardiometabolic risk factors and risk prediction than self-reported physical activity levels. Diab Vasc Dis Res. 2015;12(6):428-435. doi: 10.1177/1479164115599907</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Juraschek SP, Blaha MJ, Blumenthal RS, et al. Cardiorespiratory fitness and incident diabetes: the FIT (Henry Ford ExercIse Testing) project. Diabetes Care. 2015;38(6):1075-1081. doi: 10.2337/dc14-2714</mixed-citation><mixed-citation xml:lang="en">Juraschek SP, Blaha MJ, Blumenthal RS, et al. Cardiorespiratory fitness and incident diabetes: the FIT (Henry Ford ExercIse Testing) project. Diabetes Care. 2015;38(6):1075-1081. doi: 10.2337/dc14-2714</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Qin L, Knol MJ, Corpeleijn E, Stolk RP. Does physical activity modify the risk of obesity for type 2 diabetes: a review of epidemiological data. Eur J Epidemiol. 2010;25(1):5-12. doi: 10.1007/s10654-009-9395-y</mixed-citation><mixed-citation xml:lang="en">Qin L, Knol MJ, Corpeleijn E, Stolk RP. Does physical activity modify the risk of obesity for type 2 diabetes: a review of epidemiological data. Eur J Epidemiol. 2010;25(1):5-12. doi: 10.1007/s10654-009-9395-y</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Lee DC, Park I, Jun TW, et al. Physical activity and body mass index and their associations with the development of type 2 diabetes in korean men. Am J Epidemiol. 2012;176(1):43-51. doi: 10.1093/aje/kwr471</mixed-citation><mixed-citation xml:lang="en">Lee DC, Park I, Jun TW, et al. Physical activity and body mass index and their associations with the development of type 2 diabetes in korean men. Am J Epidemiol. 2012;176(1):43-51. doi: 10.1093/aje/kwr471</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Wei M. The Association between Cardiorespiratory Fitness and Impaired Fasting Glucose and Type 2 Diabetes Mellitus in Men. Annals of Internal Medicine. 1999;130(2):89. doi: 10.7326/0003-4819-130-2-199901190-00002</mixed-citation><mixed-citation xml:lang="en">Wei M. The Association between Cardiorespiratory Fitness and Impaired Fasting Glucose and Type 2 Diabetes Mellitus in Men. Annals of Internal Medicine. 1999;130(2):89. doi: 10.7326/0003-4819-130-2-199901190-00002</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Jeon CY, Lokken RP, Hu FB, van Dam RM. Physical activity of moderate intensity and risk of type 2 diabetes: a systematic review. Diabetes Care. 2007;30(3):744-752. doi: 10.2337/dc06-1842</mixed-citation><mixed-citation xml:lang="en">Jeon CY, Lokken RP, Hu FB, van Dam RM. Physical activity of moderate intensity and risk of type 2 diabetes: a systematic review. Diabetes Care. 2007;30(3):744-752. doi: 10.2337/dc06-1842</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Petersen CB, Bauman A, Tolstrup JS. Total sitting time and the risk of incident diabetes in Danish adults (the DANHES cohort) over 5 years: a prospective study. Br J Sports Med. 2016;50(22):1382-1387. doi: 10.1136/bjsports-2015-095648</mixed-citation><mixed-citation xml:lang="en">Petersen CB, Bauman A, Tolstrup JS. Total sitting time and the risk of incident diabetes in Danish adults (the DANHES cohort) over 5 years: a prospective study. Br J Sports Med. 2016;50(22):1382-1387. doi: 10.1136/bjsports-2015-095648</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Williams PT, Thompson PD. Effects of Statin Therapy on Exercise Levels in Participants in the National Runners’ and Walkers’ Health Study. Mayo Clin Proc. 2015;90(10):1338-1347. doi: 10.1016/j.mayocp.2015.06.019</mixed-citation><mixed-citation xml:lang="en">Williams PT, Thompson PD. Effects of Statin Therapy on Exercise Levels in Participants in the National Runners’ and Walkers’ Health Study. Mayo Clin Proc. 2015;90(10):1338-1347. doi: 10.1016/j.mayocp.2015.06.019</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Wei M. The Association between Cardiorespiratory Fitness and Impaired Fasting Glucose and Type 2 Diabetes Mellitus in Men. Annals of Internal Medicine. 1999;130(2):89. doi: 10.7326/0003-4819-130-2-199901190-00002</mixed-citation><mixed-citation xml:lang="en">Wei M. The Association between Cardiorespiratory Fitness and Impaired Fasting Glucose and Type 2 Diabetes Mellitus in Men. Annals of Internal Medicine. 1999;130(2):89. doi: 10.7326/0003-4819-130-2-199901190-00002</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Batty GD, Shipley MJ, Marmot M, Davey Smith G. Physical activity and cause-specific mortality in men with Type 2 diabetes/impaired glucose tolerance: evidence from the Whitehall study. Diabetic Medicine. 2002;19(7):580-588. doi: 10.1046/j.1464-5491.2002.00748.x</mixed-citation><mixed-citation xml:lang="en">Batty GD, Shipley MJ, Marmot M, Davey Smith G. Physical activity and cause-specific mortality in men with Type 2 diabetes/impaired glucose tolerance: evidence from the Whitehall study. Diabetic Medicine. 2002;19(7):580-588. doi: 10.1046/j.1464-5491.2002.00748.x</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru">Gregg EW, Gerzoff RB, Caspersen CJ, et al. Relationship of walking to mortality among US adults with diabetes. Arch Intern Med. 2003;163(12):1440-1447. doi: 10.1001/archinte.163.12.1440</mixed-citation><mixed-citation xml:lang="en">Gregg EW, Gerzoff RB, Caspersen CJ, et al. Relationship of walking to mortality among US adults with diabetes. Arch Intern Med. 2003;163(12):1440-1447. doi: 10.1001/archinte.163.12.1440</mixed-citation></citation-alternatives></ref><ref id="cit33"><label>33</label><citation-alternatives><mixed-citation xml:lang="ru">Tanasescu M, Leitzmann MF, Rimm EB, Hu FB. Physical activity in relation to cardiovascular disease and total mortality among men with type 2 diabetes. Circulation. 2003;107(19):2435-2439. doi: 10.1161/01.CIR.0000066906.11109.1F</mixed-citation><mixed-citation xml:lang="en">Tanasescu M, Leitzmann MF, Rimm EB, Hu FB. Physical activity in relation to cardiovascular disease and total mortality among men with type 2 diabetes. Circulation. 2003;107(19):2435-2439. doi: 10.1161/01.CIR.0000066906.11109.1F</mixed-citation></citation-alternatives></ref><ref id="cit34"><label>34</label><citation-alternatives><mixed-citation xml:lang="ru">Hu G, Eriksson J, Barengo NC, et al. Occupational, commuting, and leisure-time physical activity in relation to total and cardiovascular mortality among Finnish subjects with type 2 diabetes. Circulation. 2004;110(6):666-673. doi: 10.1161/01.CIR.0000138102.23783.94</mixed-citation><mixed-citation xml:lang="en">Hu G, Eriksson J, Barengo NC, et al. Occupational, commuting, and leisure-time physical activity in relation to total and cardiovascular mortality among Finnish subjects with type 2 diabetes. Circulation. 2004;110(6):666-673. doi: 10.1161/01.CIR.0000138102.23783.94</mixed-citation></citation-alternatives></ref><ref id="cit35"><label>35</label><citation-alternatives><mixed-citation xml:lang="ru">Hu G, Jousilahti P, Barengo NC, et al. Physical Activity, Cardiovascular Risk Factors, and Mortality Among Finnish Adults With Diabetes. Diabetes Care. 2005;28(4):799-805. doi: 10.2337/diacare.28.4.799</mixed-citation><mixed-citation xml:lang="en">Hu G, Jousilahti P, Barengo NC, et al. Physical Activity, Cardiovascular Risk Factors, and Mortality Among Finnish Adults With Diabetes. Diabetes Care. 2005;28(4):799-805. doi: 10.2337/diacare.28.4.799</mixed-citation></citation-alternatives></ref><ref id="cit36"><label>36</label><citation-alternatives><mixed-citation xml:lang="ru">Jonker JT, De Laet C, Franco OH, et al. Physical Activity and Life Expectancy With and Without Diabetes: Life table analysis of the Framingham Heart Study. Diabetes Care. 2005;29(1):38-43. doi: 10.2337/diacare.29.01.06.dc05-0985</mixed-citation><mixed-citation xml:lang="en">Jonker JT, De Laet C, Franco OH, et al. Physical Activity and Life Expectancy With and Without Diabetes: Life table analysis of the Framingham Heart Study. Diabetes Care. 2005;29(1):38-43. doi: 10.2337/diacare.29.01.06.dc05-0985</mixed-citation></citation-alternatives></ref><ref id="cit37"><label>37</label><citation-alternatives><mixed-citation xml:lang="ru">Nelson KM, Boyko EJ, Koepsell T. All-cause mortality risk among a national sample of individuals with diabetes. Diabetes Care. 2010;33(11):2360-2364. doi: 10.2337/dc10-0846</mixed-citation><mixed-citation xml:lang="en">Nelson KM, Boyko EJ, Koepsell T. All-cause mortality risk among a national sample of individuals with diabetes. Diabetes Care. 2010;33(11):2360-2364. doi: 10.2337/dc10-0846</mixed-citation></citation-alternatives></ref><ref id="cit38"><label>38</label><citation-alternatives><mixed-citation xml:lang="ru">Sluik D, Buijsse B, Muckelbauer R, et al. Physical Activity and Mortality in Individuals With Diabetes Mellitus: A Prospective Study and Meta-analysis. Arch Intern Med. 2012;172(17):1285-1295. doi: 10.1001/archinternmed.2012.3130</mixed-citation><mixed-citation xml:lang="en">Sluik D, Buijsse B, Muckelbauer R, et al. Physical Activity and Mortality in Individuals With Diabetes Mellitus: A Prospective Study and Meta-analysis. Arch Intern Med. 2012;172(17):1285-1295. doi: 10.1001/archinternmed.2012.3130</mixed-citation></citation-alternatives></ref><ref id="cit39"><label>39</label><citation-alternatives><mixed-citation xml:lang="ru">Cassidy S, Chau JY, Catt M, et al. Cross-sectional study of diet, physical activity, television viewing and sleep duration in 233,110 adults from the UK Biobank; the behavioural phenotype of cardiovascular disease and type 2 diabetes. BMJ Open. 2016;6(3):e010038. doi: 10.1136/bmjopen-2015-010038</mixed-citation><mixed-citation xml:lang="en">Cassidy S, Chau JY, Catt M, et al. Cross-sectional study of diet, physical activity, television viewing and sleep duration in 233,110 adults from the UK Biobank; the behavioural phenotype of cardiovascular disease and type 2 diabetes. BMJ Open. 2016;6(3):e010038. doi: 10.1136/bmjopen-2015-010038</mixed-citation></citation-alternatives></ref><ref id="cit40"><label>40</label><citation-alternatives><mixed-citation xml:lang="ru">Sadarangani KP, Hamer M, Mindell JS, et al. Physical activity and risk of all-cause and cardiovascular disease mortality in diabetic adults from Great Britain: pooled analysis of 10 population-based cohorts. Diabetes Care. 2014;37(4):1016-1023. doi: 10.2337/dc13-1816</mixed-citation><mixed-citation xml:lang="en">Sadarangani KP, Hamer M, Mindell JS, et al. Physical activity and risk of all-cause and cardiovascular disease mortality in diabetic adults from Great Britain: pooled analysis of 10 population-based cohorts. Diabetes Care. 2014;37(4):1016-1023. doi: 10.2337/dc13-1816</mixed-citation></citation-alternatives></ref><ref id="cit41"><label>41</label><citation-alternatives><mixed-citation xml:lang="ru">Aune D, Norat T, Leitzmann M, et al. Physical activity and the risk of type 2 diabetes: a systematic review and dose-response meta-analysis. Eur J Epidemiol. 2015;30(7):529-542. doi: 10.1007/s10654-015-0056-z</mixed-citation><mixed-citation xml:lang="en">Aune D, Norat T, Leitzmann M, et al. Physical activity and the risk of type 2 diabetes: a systematic review and dose-response meta-analysis. Eur J Epidemiol. 2015;30(7):529-542. doi: 10.1007/s10654-015-0056-z</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
