diaendoСахарный диабетDiabetes mellitus2072-03512072-0378Endocrinology research centre10.14341/DM7760diaendo-7760Research ArticleДиагностика, контроль, лечениеDiagnosis, control, treatmentДинамика развития методов контроля гликемии от инвазивных к неинвазивным. Актуальные перспективыThe dynamics of invasive and noninvasive blood glucose monitoring methods: Recent trendshttps://orcid.org/0000-0002-0559-697XБабенкоАлина ЮрьевнаBabenkoAlina Yur'evna

доктор медицинских наук, заведующая НИЛ диабетологии института эндокринологии

alina_babenko@mail.ruhttps://orcid.org/0000-0002-6531-767XКононоваЮлия АлексеевнаKononovaYulia Alexeevna

аспирант института эндокринологии СЗФМИЦ им.В.А.Алмазова

graduate student of institute of endocrinology of Federal Almazov North-West Medical Research Centre

yukonon@mail.ruhttps://orcid.org/0000-0001-6587-4313ЦиберкинАлександр ИвановичTsiberkinAlexandr Ivanovich

клинический ординатор института эндокринологии СЗФМИЦ им.В.А.Алмазован

clinical intern of institute of endocrinology of Federal Almazov North-West Medical Research Centre

tsibern1@gmail.comhttps://orcid.org/0000-0001-7261-8350ХодзицкийМихаил КонстантиновичKhodzitskyMichail Konstantinovich

руководитель лаборатории "Терагерцовой биомедицины"

ответственный исполнитель Международного Института

Фотоники и Оптоинформатики,

доцент, к.ф.-м.н, кафедра Фотоники и Оптоинформатики, Университетf ИТМО 

 

Chief of Terahertz Biomedicine Laboratory,

 

Vice-chief of International Institute of

Photonics and Optoinformatics, Associate professor, Photonics and Optical Information Technologies Dept. ITMO University

 

khodzitskiy@yandex.ruГриневаЕлена НиколаевнаGrinevaElena Nilkolaevna

директор института эндокринологии СЗФМИЦ им.В.А.Алмазова, д.м.н., профессор

director of institute of endocrinology of Federal Almazov North-West Medical Research Centre, MD, professor

grineva_e@mail.ruФГБУ Северо-Западный федеральный медицинский исследовательский центр им. В.А. Алмазова; ФГАОУ ВО Санкт-Петербургский национальный исследовательский университет информационных технологий, механики и оптикиРоссияV.A. Almazov Federal North-West Medical Research Centre; Saint-Petersburg National Research University of Information Technologies, Mechanics and OpticsRussian FederationФГБУ Северо-Западный федеральный медицинский исследовательский центр им. В.А. АлмазоваРоссияV.A. Almazov Federal North-West Medical Research CentreRussian FederationФГАОУ ВО Санкт-Петербургский национальный исследовательский университет информационных технологий, механики и оптикиРоссияSaint-Petersburg National Research University of Information Technologies, Mechanics and OpticsRussian Federation201631122016195397405Copyright © Бабенко А.Ю., Кононова Ю.А., Циберкин А.И., Ходзицкий М.К., Гринева Е.Н., 20162016Бабенко А.Ю., Кононова Ю.А., Циберкин А.И., Ходзицкий М.К., Гринева Е.Н.Babenko A.Y., Kononova Y.A., Tsiberkin A.I., Khodzitsky M.K., Grineva E.N.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.dia-endojournals.ru/jour/article/view/7760

Улучшение прогноза пациентов, страдающих диабетом 2 типа, в высокой степени определяется адекватным контролем всех параметров гликемии (коррекция гипер- и гипогликемии, нормализация вариабельности гликемии). Для полноценной идентификации и своевременной коррекции всех отклонений уровня гликемии чрезвычайно важен ее самоконтроль. Используемые в настоящее время для самоконтроля методы имеют ряд существенных недостатков, ограничивающих их использование. Наиболее значимые проблемы существующих методов самоконтроля включают недостаточную точность, инвазивность, высокую стоимость, что приводит к отсутствию должной частоты измерения уровня гликемии и, соответственно, вносит трудности в компенсацию сахарного диабета. Эти факторы определяют необходимость создания неинвазивных, рентабельных и высокоточных методов оценки гликемии. Для неинвазивного определения уровня глюкозы предложено большое количество различных подходов, начиная от оптических методов анализа, заканчивая ультразвуковыми и биоимпедансными методиками. Несмотря на то, что первые разработки в области неинвазивного определения глюкозы появились около 30 лет назад, до настоящего момента большинство методик находится на ранних стадиях развития и не может быть использовано в клинической практике. В настоящем обзоре представлен анализ наиболее перспективных разработок в этом направлении.

Improved prognoses of patients with type 2 diabetes are primarily determined by the extent of blood glucose control (correction of both hyper- and hypoglycemia and normalization of blood glucose levels). The proper identification and timely correction of abnormal blood glucose levels require frequent blood glucose monitoring by the patient. Currently used methods for the self-monitoring of blood glucose have significant drawbacks that limit their use. The most significant problems with these methods include insufficient accuracy, invasiveness and high cost, leading to noncompliance and difficult assessment of disease status. Such factors underscore the need for a noninvasive, cost-effective and highly accurate method to measure blood glucose levels. There are several different approaches for the noninvasive measurement of blood glucose levels, including optical analysis, ultrasound and bioimpedance. The concept of a noninvasive glucometer was launched more than 30 years ago. Nevertheless, most noninvasive technologies are still in early stages of development and are not used in clinical practice. This review describers the most promising developments in this area.

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The authors declare that there are no conflicts of interest present.