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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">diaendo</journal-id><journal-title-group><journal-title xml:lang="ru">Сахарный диабет</journal-title><trans-title-group xml:lang="en"><trans-title>Diabetes mellitus</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2072-0351</issn><issn pub-type="epub">2072-0378</issn><publisher><publisher-name>Endocrinology research centre</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14341/DM2001438-41</article-id><article-id custom-type="elpub" pub-id-type="custom">diaendo-7480</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Articles</subject></subj-group></article-categories><title-group><article-title>Клинические преимущества Старликса? в лечении больных сахарным диабетом 2 типа</article-title><trans-title-group xml:lang="en"><trans-title>Klinicheskie preimushchestva Starliksa? v lechenii bol'nykh sakharnym diabetom 2 tipa</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мкртумян</surname><given-names>Ашот Мусаелович</given-names></name><name name-style="western" xml:lang="en"><surname>Mkrtumyan</surname><given-names>Ashot Musaelovich</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кафедра эндокринологии</p></bio><bio xml:lang="en"/><email xlink:type="simple">-</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>ФППО ММ А им. И. М. Сеченова М3 РФ</institution></aff><pub-date pub-type="collection"><year>2001</year></pub-date><pub-date pub-type="epub"><day>15</day><month>12</month><year>2001</year></pub-date><volume>4</volume><issue>4</issue><issue-title>№4 (2001)</issue-title><fpage>38</fpage><lpage>41</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Мкртумян А.М., 2001</copyright-statement><copyright-year>2001</copyright-year><copyright-holder xml:lang="ru">Мкртумян А.М.</copyright-holder><copyright-holder xml:lang="en">Mkrtumyan A.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.dia-endojournals.ru/jour/article/view/7480">https://www.dia-endojournals.ru/jour/article/view/7480</self-uri><abstract><p>Основываясь на данных исследований, доказывающих важную роль аминокислот (помимо глюкозы) в процессе секреции инсулина бета-клетками непосредственно в процессе еды, было начато изучение сахароснижающей активности аналогов фенилаланина, увенчавшееся синтезом натеглинида. Настоящая статья посвящена описанию молекулярного механизма действия препарата, доказательствам его клинической эффективности и особенностей применения.</p></abstract><kwd-group xml:lang="ru"><kwd>Старликс</kwd><kwd>сахарный диабет 2 типа</kwd><kwd>лечение</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Diabetes Саге, 1997,20, 1183-1197.</mixed-citation><mixed-citation xml:lang="en">Diabetes Саге, 1997,20, 1183-1197.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Unger RH. Science, 1991,251, 1200-1205.</mixed-citation><mixed-citation xml:lang="en">Unger RH. Science, 1991,251, 1200-1205.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Балаболкин М.И. 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