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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">diaendo</journal-id><journal-title-group><journal-title xml:lang="ru">Сахарный диабет</journal-title><trans-title-group xml:lang="en"><trans-title>Diabetes mellitus</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2072-0351</issn><issn pub-type="epub">2072-0378</issn><publisher><publisher-name>Endocrinology research centre</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14341/DM2015357-69</article-id><article-id custom-type="elpub" pub-id-type="custom">diaendo-6859</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Синдром диабетической стопы</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Diabetic foot</subject></subj-group></article-categories><title-group><article-title>Особенности клинического течения критической ишемии нижних конечностей и роль эндоваскулярной реваскуляризации у больных сахарным диабетом</article-title><trans-title-group xml:lang="en"><trans-title>The clinical course of critical limb ischaemia and the role of endovascular revascularisation in patients with diabetes</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бондаренко</surname><given-names>Ольга Николаевна</given-names></name><name name-style="western" xml:lang="en"><surname>Bondarenko</surname><given-names>Olga Nikolaevna</given-names></name></name-alternatives><bio xml:lang="ru"><p>кандидат медицинских наук, старший научный сотрудник отделения диабетической стопы</p></bio><bio xml:lang="en"><p>MD, PhD, Cheif Researcher at Diabetic foot dapertment, Diabetes institute</p></bio><email xlink:type="simple">olga-foot@bk.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Галстян</surname><given-names>Гагик Радикович</given-names></name><name name-style="western" xml:lang="en"><surname>Galstyan</surname><given-names>Gagik Radikovich</given-names></name></name-alternatives><bio xml:lang="ru"><p>доктор медицинских наук, профессор, заведующий отделением диабетической стопы</p></bio><bio xml:lang="en"><p>MD, PhD, Head of the Diabetic foot department, Diabetes institute</p></bio><email xlink:type="simple">mariagrishina2006@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8175-7886</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дедов</surname><given-names>Иван Иванович</given-names></name><name name-style="western" xml:lang="en"><surname>Dedov</surname><given-names>Ivan Ivanovich</given-names></name></name-alternatives><bio xml:lang="ru"><p>академик РАН, директор ФГБУ «Эндокринологический научный центр» Минздрава России</p></bio><bio xml:lang="en"><p>MD, PhD, Professor, academician of Russian academy of Sciences, Director of Endocrinology Research Centre</p></bio><email xlink:type="simple">dedov@endocrincentr.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ "Эндокринологический научный центр" Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Endocrinology Research Centre</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2015</year></pub-date><pub-date pub-type="epub"><day>12</day><month>05</month><year>2015</year></pub-date><volume>18</volume><issue>3</issue><fpage>57</fpage><lpage>69</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Бондаренко О.Н., Галстян Г.Р., Дедов И.И., 2015</copyright-statement><copyright-year>2015</copyright-year><copyright-holder xml:lang="ru">Бондаренко О.Н., Галстян Г.Р., Дедов И.И.</copyright-holder><copyright-holder xml:lang="en">Bondarenko O.N., Galstyan G.R., Dedov I.I.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.dia-endojournals.ru/jour/article/view/6859">https://www.dia-endojournals.ru/jour/article/view/6859</self-uri><abstract><p>Критическая ишемия нижних конечностей (КИНК) до сих пор является основной причиной ампутаций у больных сахарным диабетом (СД). Большая распространенность КИНК среди пациентов с СД ассоциирована с клиническими и морфологическими особенностями заболевания периферических артерий. Чрескожная транслюминальная баллонная ангиопластика (ЧТБА) является основным методом лечения КИНК. Тем не менее, возможность восстановления артериального кровотока не всегда оценивается адекватно и своевременно, приводя к потере конечности. Низкая первичная проходимость, несмотря на оптимальные клинические исходы, является отличительной особенностью эндоваскулярной ЧТБА, особенно у пациентов с СД. Таким образом, определение показаний к восстановлению кровотока, оценка технического успеха и клинических исходов эндоваскулярных вмешательств у пациентов с СД во многих случаях может представлять трудную задачу и требовать междисциплинарного подхода.</p></abstract><trans-abstract xml:lang="en"><p>Recent data suggest that chronic critical limb ischaemia (CLI) is the most important reason for amputation among diabetic patients. The high prevalence of CLI in this patient group is associated with specific clinical and morphological properties of peripheral arterial disease. Percutaneous transluminal angioplasty is an appropriate primary therapy, but it is not considered early in the disease process, and is instead reserved as a limb salvage strategy. Low primary patency, despite optimal clinical effects, remains a typical issue of percutaneous transluminal angioplasty for diabetic patients in particular. Thus, the indications, technical success and clinical results of endovascular revascularisation need to be clarified in patients with diabetes. Although difficult, the procedure can be effective through a multidisciplinary approach.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>сахарный диабет</kwd><kwd>заболевания периферических артерий</kwd><kwd>критическая ишемия нижних конечностей</kwd><kwd>эндоваскулярное лечение артерий нижних конечностей</kwd></kwd-group><kwd-group xml:lang="en"><kwd>diabetes</kwd><kwd>critical limb ischemia</kwd><kwd>endovascular revascularization</kwd><kwd>arterial patency</kwd><kwd>limb salvage</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Lepantalo M, Matzke S. Outcome of unreconstructed chronic critical leg ischemia. Eur J Vasc Endovasc Surg. 1996;11(2):153-157. doi: 10.1016/S1078-5884(96)80044-X</mixed-citation><mixed-citation xml:lang="en">Lepantalo M, Matzke S. Outcome of unreconstructed chronic critical leg ischemia. 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