diaendoСахарный диабетDiabetes mellitus2072-03512072-0378Endocrinology research centre10.14341/2072-0351-6121diaendo-6121Research ArticleСтатьиArticlesСовременные аспекты патогенеза пародонтита у больных сахарным диабетомSovremennye aspekty patogenezaparodontita u bol'nykh sakharnym diabetomГригорянК РGrigoryanK R-БарерГ МBarerG M-ГригорянОльга РафаэльевнаGrigoryanOlga Rafael'evna-МельниченкоГалина АфанасьеваMel'nichenkoGalina Afanas'evna-ДедовИван ИвановичDedovIvan Ivanovich-Московский государственный медико-стоматологический университет, МоскваГУ Эндокринологический научный центр РАМН, МоскваEndocrinology Research Centre, Moscow20061506200692№2 (2006)6468Copyright © Григорян К.Р., Барер Г.М., Григорян О.Р., Мельниченко Г.А., Дедов И.И., 20062006Григорян К.Р., Барер Г.М., Григорян О.Р., Мельниченко Г.А., Дедов И.И.Grigoryan K.R., Barer G.M., Grigoryan O.R., Mel'nichenko G.A., Dedov I.I.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.dia-endojournals.ru/jour/article/view/6121

В настоящее время среди лиц обоего пола, находящихся в репродуктивном периоде, резко повысилась распространенность заболеваний пародонта. По данным ВОЗ (1990), наличие заболеваний пародонта (по сравнению с осложнениями кариеса) увеличивает в 5 раз развитие функциональных расстройств зубочелюстной системы, приводящих к потере зубов. Общеизвестно, что у больных СД пародонтит встречается практически в 100% случаев и характеризуется агрессивным характером течения. Данный патологический процесс имеет уникальную морфологическую структуру, значительно отличающуюся от воспалительных заболеваний пародонта у лиц без СД. Частота и тяжесть указанного процесса имеет прямую корреляционную зависимость от длительности нарушений углеводного обмена.

пародонтитпатогенезсахарный диабетReferencesKaslow R.A. Infections in diabetics. Diabetes in America.// NIH Publication №. 85, p.1468.Kaslow R.A. Infections in diabetics. Diabetes in America.// NIH Publication №. 85, p.1468.Wilson R.M. Infection and diabetes mellitus. // Textbook of Diabetes Blackwell Scientific Publications, London: 813-818.Wilson R.M. Infection and diabetes mellitus. // Textbook of Diabetes Blackwell Scientific Publications, London: 813-818.Rayfield E.J., Ault M.J., Keusch G.T., Brothers M.J., Nechemias C., Smith H. Infection and diabetes: the case for glucose control.// American Journal of Medicine, 1982., № 72:439-450.Rayfield E.J., Ault M.J., Keusch G.T., Brothers M.J., Nechemias C., Smith H. Infection and diabetes: the case for glucose control.// American Journal of Medicine, 1982., № 72:439-450.Wheat J.L. Infection in diabetes melllitus.// Diabetes Care, 1980, № 3: 187-197.Wheat J.L. Infection in diabetes melllitus.// Diabetes Care, 1980, № 3: 187-197.Lewis R.P., Sutter V.L., Finegold S.M. Bone infections involving anaerobic bacteria.// Medicine, 2003, 57: 279-305.Lewis R.P., Sutter V.L., Finegold S.M. Bone infections involving anaerobic bacteria.// Medicine, 2003, 57: 279-305.Genco R.J. Classification and clinical and radiographic features of periodontal disease. // Contempory periodontics. St. Louis: Mosby, 2004, 63-81.Genco R.J. Classification and clinical and radiographic features of periodontal disease. // Contempory periodontics. St. Louis: Mosby, 2004, 63-81.Page R.C. Gingivitis.// J Clin. Perio. № 13: 345-355.Page R.C. Gingivitis.// J Clin. Perio. № 13: 345-355.Shah H.N., Collins D.M. Proposal for classification of Bacteroides asaccharolyticus, Bacteroides gingivalis, and Bacteroides endodontalis in a new genus, Porphyromonas.// International Journal of Systematic Bacteriology, 2002, № 38: 128-131.Shah H.N., Collins D.M. Proposal for classification of Bacteroides asaccharolyticus, Bacteroides gingivalis, and Bacteroides endodontalis in a new genus, Porphyromonas.// International Journal of Systematic Bacteriology, 2002, № 38: 128-131.Shah H.N., Collins D.M. Prevotella, a new genus to include Bacteroides melaninogenicus and related species formerly classified in the genus Bacteroides. // International Journal of Systematic Bacteriology, № 40: 205-208.Shah H.N., Collins D.M. Prevotella, a new genus to include Bacteroides melaninogenicus and related species formerly classified in the genus Bacteroides. // International Journal of Systematic Bacteriology, № 40: 205-208.Dzink J.L., Socransky S.S., Haffajee A.D. The predominant cultivable microbiota of active and inactive lesions of destructive periodontal diseases. // Journal of Clinical Periodontology № 15: 316-323.Dzink J.L., Socransky S.S., Haffajee A.D. The predominant cultivable microbiota of active and inactive lesions of destructive periodontal diseases. // Journal of Clinical Periodontology № 15: 316-323.Loesche W.J., Syed S.A., Schmidt E., Morrison E.C. Bacterial profiles of subgingival plaques in periodontitis. // Periodontol, № 56: 447-156.Loesche W.J., Syed S.A., Schmidt E., Morrison E.C. Bacterial profiles of subgingival plaques in periodontitis. // Periodontol, № 56: 447-156.Slots J., Genco R.J. Black-pigmented Bacteroides species, Capnocytophaga species, and Actinobacillus actinomycetemcomitans in human periodontal disease: Virulence factors in colonization, survival and tissue destruction.// J Dent Res., 1980, № 63: 412-421.Slots J., Genco R.J. Black-pigmented Bacteroides species, Capnocytophaga species, and Actinobacillus actinomycetemcomitans in human periodontal disease: Virulence factors in colonization, survival and tissue destruction.// J Dent Res., 1980, № 63: 412-421.Moore W.E. Microbiology of periodontal disease // Journal of Periodontolal Research, 1987; № 22: 335-341.Moore W.E. Microbiology of periodontal disease // Journal of Periodontolal Research, 1987; № 22: 335-341.Zambon J.J. Actinobacillus actinomycetemcomitans in human periodontal disease // Journal of Clinical Periodontology, 1996, № 12:1-20.Zambon J.J. Actinobacillus actinomycetemcomitans in human periodontal disease // Journal of Clinical Periodontology, 1996, № 12:1-20.Kornman K.S., Robertson P.B. Clinical and microbiological evaluation of therapy for juvenile periodontitis // Journal of Periodontic Research, 1988, № 56: 443-446.Kornman K.S., Robertson P.B. Clinical and microbiological evaluation of therapy for juvenile periodontitis // Journal of Periodontic Research, 1988, № 56: 443-446.Slots J., Hafstrom C., Rosling B., Dahlen G. Detection of Actinobacillus actinomycetemcomitans and Bacteroides gingivalis in subgingival smears by the indirect fluorescent-antibody technique // Journal of Periodontolal Research, 1988 № 20: 613-620.Slots J., Hafstrom C., Rosling B., Dahlen G. Detection of Actinobacillus actinomycetemcomitans and Bacteroides gingivalis in subgingival smears by the indirect fluorescent-antibody technique // Journal of Periodontolal Research, 1988 № 20: 613-620.Genco R.J., Zambon J.J., Christersson L.A. The origin of periodontal infections // Advances in Dental Research, 1988, № 2: 245-259.Genco R.J., Zambon J.J., Christersson L.A. The origin of periodontal infections // Advances in Dental Research, 1988, № 2: 245-259.Loe H., Morrison E. Periodontal health and disease in young people: screening for priority care// International Dental Journal № 36:162-167.Loe H., Morrison E. Periodontal health and disease in young people: screening for priority care// International Dental Journal № 36:162-167.Socransky S.S., Haffajee A.D., Goodson J.M., Lindhe J. New concepts of destructive periodontal disease // Journal of Clinical Periodontology, № 11: 21-32.Socransky S.S., Haffajee A.D., Goodson J.M., Lindhe J. New concepts of destructive periodontal disease // Journal of Clinical Periodontology, № 11: 21-32.Miller L. S., Manwell M. A., Newbold D., Reding M. E., Rasheed A., Blodgett J., Kornman K. S. The relationship between reduction in periodontal inflammation and diabetes control: A report of 9 cases. // Journal of Periodontolal Research 1992; vol. 63, p. 843-848.Miller L. S., Manwell M. A., Newbold D., Reding M. E., Rasheed A., Blodgett J., Kornman K. S. The relationship between reduction in periodontal inflammation and diabetes control: A report of 9 cases. // Journal of Periodontolal Research 1992; vol. 63, p. 843-848.Albandar J.M., Kingman A. Gingival recession, gingival bleeding, and dental calculus in adults 30 years of age and older in the United States, 1988-1994// Journal of Periodontology № 70: 30-43.Albandar J.M., Kingman A. Gingival recession, gingival bleeding, and dental calculus in adults 30 years of age and older in the United States, 1988-1994// Journal of Periodontology № 70: 30-43.Albandar J.M., Brunelle J.A., Kingman A. Destructive periodontal disease in adults 30 years of age and older in the United States, 1988-1994 // Journal of Periodontology, 1999; № 70(1): 13-29.Albandar J.M., Brunelle J.A., Kingman A. Destructive periodontal disease in adults 30 years of age and older in the United States, 1988-1994 // Journal of Periodontology, 1999; № 70(1): 13-29.Goteiner D., Vogel R., Deasy M., Goteiner С. Periodontal and caries experience in children with insulin-dependent diabetes mellitus// Journal of the American Dental Association, 1999, № 113: 277-279.Goteiner D., Vogel R., Deasy M., Goteiner С. Periodontal and caries experience in children with insulin-dependent diabetes mellitus// Journal of the American Dental Association, 1999, № 113: 277-279.Harrison R., Bowen W.H. Periodontal health, dental caries, and metabolic control in insulin-dependent diabetic children and adolescents// Pediatric Dentistry, 1996, № 9: 283-286.Harrison R., Bowen W.H. Periodontal health, dental caries, and metabolic control in insulin-dependent diabetic children and adolescents// Pediatric Dentistry, 1996, № 9: 283-286.Novaes Jr. A.B., de Moraes N., Novaes A.B. Manifestations of insulindependent diabetes mellitus in the periodontium of young brazilian patients // Journal of Periodontology, № 62:116-122.Novaes Jr. A.B., de Moraes N., Novaes A.B. Manifestations of insulindependent diabetes mellitus in the periodontium of young brazilian patients // Journal of Periodontology, № 62:116-122.

The authors declare that there are no conflicts of interest present.