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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">diaendo</journal-id><journal-title-group><journal-title xml:lang="ru">Сахарный диабет</journal-title><trans-title-group xml:lang="en"><trans-title>Diabetes mellitus</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2072-0351</issn><issn pub-type="epub">2072-0378</issn><publisher><publisher-name>Endocrinology research centre</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14341/2072-0351-6117</article-id><article-id custom-type="elpub" pub-id-type="custom">diaendo-6117</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Articles</subject></subj-group></article-categories><title-group><article-title>Использование инкретинов в лечении сахарного диабета 2 типа - вчерашняя мечта, близкая к реальности сегодня</article-title><trans-title-group xml:lang="en"><trans-title>Ispol'zovanie inkretinov v lecheniisakharnogo diabeta 2 tipa - vcherashnyaya mechta,blizkaya k real'nosti segodnya</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мкртумян</surname><given-names>Ашот Мусаелович</given-names></name><name name-style="western" xml:lang="en"><surname>Mkrtumyan</surname><given-names>Ashot Musaelovich</given-names></name></name-alternatives><email xlink:type="simple">-</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бирюкова</surname><given-names>Елена Валерьевна</given-names></name><name name-style="western" xml:lang="en"><surname>Biryukova</surname><given-names>Elena Valer'evna</given-names></name></name-alternatives><email xlink:type="simple">-</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>Московский государственный медико-стоматологический университет, Москва</institution></aff><pub-date pub-type="collection"><year>2006</year></pub-date><pub-date pub-type="epub"><day>15</day><month>06</month><year>2006</year></pub-date><volume>9</volume><issue>2</issue><issue-title>№2 (2006)</issue-title><fpage>34</fpage><lpage>39</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Мкртумян А.М., Бирюкова Е.В., 2006</copyright-statement><copyright-year>2006</copyright-year><copyright-holder xml:lang="ru">Мкртумян А.М., Бирюкова Е.В.</copyright-holder><copyright-holder xml:lang="en">Mkrtumyan A.M., Biryukova E.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.dia-endojournals.ru/jour/article/view/6117">https://www.dia-endojournals.ru/jour/article/view/6117</self-uri><abstract><p>Регуляция гомеостаза глюкозы осуществляется сложной мультигормональной системой, включающей гормоны поджелудочной железы и гормоны-инкретины. После открытия в 1902 г. секретина Старлинг предположил, что сигналы, возникающие в желудочно-кишечном тракте (ЖКТ) после поступления нутриентов, активно влияют на эндокринный ответ поджелудочной железы. В 1930 г. Labbarre ввел термин ?инкретин?, обозначив им гормональную активность кишечника, которая повышает эндокринную секрецию поджелудочной железы.</p></abstract><kwd-group xml:lang="ru"><kwd>инкретины</kwd><kwd>лечение</kwd><kwd>сахарный диабет 2 типа</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Aronoff SL, Berkowitz K, Shreiner B et al. Glucose metabolism and regulation: beyond insulin and glucagon. // Diabetes Spectrum. 2004;17:183-190</mixed-citation><mixed-citation xml:lang="en">Aronoff SL, Berkowitz K, Shreiner B et al. 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