diaendoСахарный диабетDiabetes mellitus2072-03512072-0378Endocrinology research centre10.14341/2072-0351-6094diaendo-6094Research ArticleСтатьиArticlesПреодоление выраженной инсулинорезистентности у больной сахарным диабетом 2 типа с помощью помповой инсулинотерапииOvercoming marked insulin resistance in a patient with type 2 diabetes mellitus by means of insulin pumptherapyАртемоваЕкатерина ВикторовнаArtemovaEkaterina Viktorovna-КононенкоИрина ВладимировнаKononenkoIrina Vladimirovnashakhtarina@bk.ruСмирноваОльга МихайловнаSmirnovaOlga Mikhailovna-МайоровАлександр ЮрьевичMayorovAlexander Yur'evich-ФГБУ Эндокринологический научный центр, МоскваEndocrinology Research Centre, Moscow201215092012153№3 (2012)110116Copyright © Артемова Е.В., Кононенко И.В., Смирнова О.М., Майоров А.Ю., 20122012Артемова Е.В., Кононенко И.В., Смирнова О.М., Майоров А.Ю.Artemova E.V., Kononenko I.V., Smirnova O.M., Mayorov A.Y.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.dia-endojournals.ru/jour/article/view/6094

У больных сахарным диабетом (СД) часто отмечается резистентность как к эндогенному, так и к экзогенно вводимомуинсулину. Преодолеть это состояние довольно трудно. В настоящей статье описан клинический случай СД 2 типа (СД2)с выраженной инсулинорезистентностью. Назначение высоких доз инсулина не позволило достичь компенсации углеводногообмена. На данном клиническом примере рассматривается возможность хронической передозировки инсулина как однойиз причин, препятствующих достижению компенсации СД, а также возможности помповой инсулинотерапии в стольнепростой клинической ситуации.

Patients with type 2 diabetes mellitus (T2DM) often feature resistance to endogenous and exogenous insulin which is a serious problemto overcome. Current paper presents clinical case of T2DM characterized by marked insulin resistance, where high dosage regimenfailed to compensate carbohydrate metabolism. Regarding the case in question we discuss chronic insulin overdosage as one of the possiblefactors to interfere with compensation of diabetes, as well as capacity of insulin pump therapy to resolve such complicated clinicalsituation.

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The authors declare that there are no conflicts of interest present.