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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">diaendo</journal-id><journal-title-group><journal-title xml:lang="ru">Сахарный диабет</journal-title><trans-title-group xml:lang="en"><trans-title>Diabetes mellitus</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2072-0351</issn><issn pub-type="epub">2072-0378</issn><publisher><publisher-name>Endocrinology research centre</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14341/2072-0351-6089</article-id><article-id custom-type="elpub" pub-id-type="custom">diaendo-6089</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Articles</subject></subj-group></article-categories><title-group><article-title>Расчет доз инсулина с помощью инсулиновой помпы: оптимизация настроек калькуляторов болюсов?</article-title><trans-title-group xml:lang="en"><trans-title>Dose adjustment in insulin pump therapy: optimization of bolus calculator settings</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Филиппов</surname><given-names>Юрий Иванович</given-names></name><name name-style="western" xml:lang="en"><surname>Filippov</surname><given-names>Yury Ivanovich</given-names></name></name-alternatives><email xlink:type="simple">yuriyivanovich@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ибрагимова</surname><given-names>Людмила Ибрагимовна</given-names></name><name name-style="western" xml:lang="en"><surname>Ibragimova</surname><given-names>Lyudmila Ibragimovna</given-names></name></name-alternatives><email xlink:type="simple">-</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Пекарева</surname><given-names>Елена Владимировна</given-names></name><name name-style="western" xml:lang="en"><surname>Pekareva</surname><given-names>Elena Vladimirovna</given-names></name></name-alternatives><email xlink:type="simple">-</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ Эндокринологический научный центр, Москва</institution></aff><aff xml:lang="en"><institution>Endocrinology Research Centre, Moscow</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2012</year></pub-date><pub-date pub-type="epub"><day>15</day><month>09</month><year>2012</year></pub-date><volume>15</volume><issue>3</issue><issue-title>№3 (2012)</issue-title><fpage>74</fpage><lpage>80</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Филиппов Ю.И., Ибрагимова Л.И., Пекарева Е.В., 2012</copyright-statement><copyright-year>2012</copyright-year><copyright-holder xml:lang="ru">Филиппов Ю.И., Ибрагимова Л.И., Пекарева Е.В.</copyright-holder><copyright-holder xml:lang="en">Filippov Y.I., Ibragimova L.I., Pekareva E.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.dia-endojournals.ru/jour/article/view/6089">https://www.dia-endojournals.ru/jour/article/view/6089</self-uri><abstract><p>Точное дозирование инсулина на еду и коррекцию гликемии - необходимое условие поддержания оптимальной концентра-ции глюкозы в крови. Современные инсулиновые дозаторы (помпы) способны не только вводить инсулин с большой точно-стью, но и рассчитывать необходимую дозу инсулина с помощью встроенных программ - калькуляторов болюсов?. Однакодля достижения необходимой точности расчетов необходим индивидуальный подбор настроек программы для каждогопациента и своевременная их коррекция. Несмотря на единый принцип работы, у разных калькуляторов болюсов? естьсущественные отличия, без учета которых подбор оптимальных настроек крайне затруднителен. Настоящий обзор посвя-щен доказательствам эффективности работы калькуляторов болюсов? в инсулиновых помпах, их сравнению и описаниюключевых отличий этих программ.</p></abstract><trans-abstract xml:lang="en"><p>Precise dosing of insulin at meals and for correction of glycemia is crucial for sustention of optimal blood glucose concentration. Moderninsulin delivery systems (such as insulin pumps) not only provide high dosing precision, but are also capable of calculating necessarydose by means of built-in software - so called bolus calculators. However, patient-oriented approach to calculator settings, as wellas their timely correction is imperative for attainment of desired precision. Though similar in their principle, various calculatorsalso feature essential peculiarities that have to be considered for optimal adjustment. The review addresses current evidence for boluscalculator efficiency, comparative analysis of these applications and description of their key distinctions.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>сахарный диабет</kwd><kwd>инсулиновые помпы</kwd><kwd>дозирование инсулина</kwd><kwd>калькулятор болюсо</kwd></kwd-group><kwd-group xml:lang="en"><kwd>diabetes mellitus</kwd><kwd>insulin pump</kwd><kwd>insulin dosing</kwd><kwd>bolus calculator</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) Research Group, Nathan DM, Zinman B, Cleary PA, Backlund JY, Genuth S, Miller R, Orchard TJ. 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