diaendoСахарный диабетDiabetes mellitus2072-03512072-0378Endocrinology research centre10.14341/2072-0351-6062diaendo-6062Research ArticleСтатьиArticlesСочетанная или изолированная трансплантация поджелудочной железы и почки в терминальной стадии диабетической нефропатииCombined or isolated transplantation of pancreas and kidney at the terminal stage of diabetic nephropathyКварацхелияМалхаз ВиктововичKvaratskheliyaMalkhaz Viktorovichmalkhaz2007@yandex.ruФГУ Эндокринологический научный центр, МоскваEndocrinological Research Centre, Moscow201015122010134№4 (2010)7682Copyright © Кварацхелия М.В., 20102010Кварацхелия М.В.Kvaratskheliya M.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.dia-endojournals.ru/jour/article/view/6062

В обзоре представлен анализ разных вариантов трансплантации поджелудочной железы и почки при терминальной почечной недоста-точности в исходе диабетической нефропатии, приведенный в современной зарубежной литературе. Сочетанную пересадку поджелу-дочной железы и почки, по данным большинства наблюдений, следует считать методом выбора у данной категории больных.При функционирующем трансплантате поджелудочной железы указанный вариант пересадки обеспечивает максимальную сохранностьпочечного трансплантата и выживаемость реципиента. Альтернативой сочетанной пересадке можно считать изолированную транс-плантацию почки от живого донора с последовательной пересадкой поджелудочной железы. При изолированной пересадке почки от труп-ного донора показатели выживаемости трансплантата и реципиента наиболее низкие

This review of current foreign literature is focused on the analysis of different variants of pancreas and kidney transplantation in patients with terminalrenal insufficiency resulting from diabetic nephropathy. Most authors consider combined pancreas and kidney transplantation to be the method ofchoice for patients with this pathology. Given the adequately functioning pancreas implant, this operation ensures excellent engaftment of the kidneyimplant and survival of the recipient. An alternative method is isolated transplantation of a kidney from a live donor with subsequent transplantationof the pancreas. Isolated transplantation of a cadaveric kidney results in transplant and recipient.

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The authors declare that there are no conflicts of interest present.