<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">diaendo</journal-id><journal-title-group><journal-title xml:lang="ru">Сахарный диабет</journal-title><trans-title-group xml:lang="en"><trans-title>Diabetes mellitus</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2072-0351</issn><issn pub-type="epub">2072-0378</issn><publisher><publisher-name>Endocrinology research centre</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14341/2072-0351-5974</article-id><article-id custom-type="elpub" pub-id-type="custom">diaendo-5974</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Articles</subject></subj-group></article-categories><title-group><article-title>Стратификация больных сахарным диабетом 2 типа по риску развития безболевой ишемии миокарда</article-title><trans-title-group xml:lang="en"><trans-title>Stratification of patients with type 2 diabetes mellitus for painless ischemic heart disease</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Волкова</surname><given-names>Наталья Ивановна</given-names></name><name name-style="western" xml:lang="en"><surname>Volkova</surname><given-names>Natalya Ivanovna</given-names></name></name-alternatives><email xlink:type="simple">-</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Харахашян</surname><given-names>Андрей Владимирович</given-names></name><name name-style="western" xml:lang="en"><surname>Kharakhashyan</surname><given-names>Andrey Vladimirovich</given-names></name></name-alternatives><email xlink:type="simple">-</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сорокина</surname><given-names>Юлия Алексеевна</given-names></name><name name-style="western" xml:lang="en"><surname>Sorokina</surname><given-names>Yulia Alekseevna</given-names></name></name-alternatives><email xlink:type="simple">-</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Давиденко</surname><given-names>Илья Юрьевич</given-names></name><name name-style="western" xml:lang="en"><surname>Davidenko</surname><given-names>Il'ya Yur'evich</given-names></name></name-alternatives><email xlink:type="simple">-</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГОУ ВПО Ростовский государственный медицинский университет, Ростов-на-Дону</institution></aff><aff xml:lang="en"><institution>Rostov State Medical University, Rostov-on-Don</institution></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Медицинский центр «Алком», Ростов-на-Дону</institution></aff><aff xml:lang="en"><institution>Medical center "Alcom", Rostov-on-Don</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2012</year></pub-date><pub-date pub-type="epub"><day>15</day><month>03</month><year>2012</year></pub-date><volume>15</volume><issue>1</issue><issue-title>№1 (2012)</issue-title><fpage>19</fpage><lpage>24</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Волкова Н.И., Харахашян А.В., Сорокина Ю.А., Давиденко И.Ю., 2012</copyright-statement><copyright-year>2012</copyright-year><copyright-holder xml:lang="ru">Волкова Н.И., Харахашян А.В., Сорокина Ю.А., Давиденко И.Ю.</copyright-holder><copyright-holder xml:lang="en">Volkova N.I., Kharakhashyan A.V., Sorokina Y.A., Davidenko I.Y.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.dia-endojournals.ru/jour/article/view/5974">https://www.dia-endojournals.ru/jour/article/view/5974</self-uri><abstract/><trans-abstract xml:lang="en"/><kwd-group xml:lang="ru"><kwd>сахарный диабет 2 типа</kwd><kwd>безболевая ишемия миокарда</kwd><kwd>факторы риска</kwd><kwd>сердечно-сосудистые заболева- ния</kwd><kwd>метод отбора</kwd></kwd-group><kwd-group xml:lang="en"><kwd>diabetes mellitus type 2</kwd><kwd>silent myocardial ischemia</kwd><kwd>risk factors</kwd><kwd>cardiovascular diseases</kwd><kwd>screening method</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Colagiuri S, Best J. Lipid-lowering therapy in people with type 2 diabetes. Curr Opin Lipidol. 2002 Dec;13(6):617-623.</mixed-citation><mixed-citation xml:lang="en">Colagiuri S, Best J. Lipid-lowering therapy in people with type 2 diabetes. Curr Opin Lipidol. 2002 Dec;13(6):617-623.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Rydén L, Standl E, Bartnik M, Van den Berghe G, Betteridge J, de Boer MJ, Cosentino F, Jönsson B, Laakso M, Malmberg K, Priori S, Ostergren J, Tuomilehto J, Thrainsdottir I, Vanhorebeek I, Stramba-Badiale M, Lindgren P, Qiao Q, Priori SG, Blanc JJ, Budaj A, Camm J, Dean V, Deckers J, Dickstein K, Lekakis J, McGregor K, Metra M, Morais J, Osterspey A, Tamargo J, Zamorano JL, Deckers JW, Bertrand M, Charbonnel B, Erdmann E, Ferrannini E, Flyvbjerg A, Gohlke H, Juanatey JR, Graham I, Monteiro PF, Parhofer K, Pyörälä K, Raz I, Schernthaner G, Volpe M, Wood D; Task Force on Diabetes and Cardiovascular Diseases of the European Society of Cardiology (ESC); European Association for the Study of Diabetes (EASD). Guidelines on diabetes, pre-diabetes, and cardiovascular diseases: executive summary. The Task Force on Diabetes and Cardiovascular Diseases of the European Society of Cardiology (ESC) and of the European Association for the Study of Diabetes (EASD). Eur Heart J. 2007 Jan;28(1):88-136.</mixed-citation><mixed-citation xml:lang="en">Rydén L, Standl E, Bartnik M, Van den Berghe G, Betteridge J, de Boer MJ, Cosentino F, Jönsson B, Laakso M, Malmberg K, Priori S, Ostergren J, Tuomilehto J, Thrainsdottir I, Vanhorebeek I, Stramba-Badiale M, Lindgren P, Qiao Q, Priori SG, Blanc JJ, Budaj A, Camm J, Dean V, Deckers J, Dickstein K, Lekakis J, McGregor K, Metra M, Morais J, Osterspey A, Tamargo J, Zamorano JL, Deckers JW, Bertrand M, Charbonnel B, Erdmann E, Ferrannini E, Flyvbjerg A, Gohlke H, Juanatey JR, Graham I, Monteiro PF, Parhofer K, Pyörälä K, Raz I, Schernthaner G, Volpe M, Wood D; Task Force on Diabetes and Cardiovascular Diseases of the European Society of Cardiology (ESC); European Association for the Study of Diabetes (EASD). Guidelines on diabetes, pre-diabetes, and cardiovascular diseases: executive summary. The Task Force on Diabetes and Cardiovascular Diseases of the European Society of Cardiology (ESC) and of the European Association for the Study of Diabetes (EASD). Eur Heart J. 2007 Jan;28(1):88-136.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Лупанов ВП, Наумов ВГ. Безболевая ишемия миокарда: диа- гностика и лечение. Сердце. 2002;1(6):276-282.</mixed-citation><mixed-citation xml:lang="en">Лупанов ВП, Наумов ВГ. Безболевая ишемия миокарда: диа- гностика и лечение. Сердце. 2002;1(6):276-282.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Верткин АЛ, Ткачева ОН, Новикова ИМ. Безболевая ишемия и диабетическая автономная нейропатия. Русский медицинский журнал. 2005; 13(20):1036-1038.</mixed-citation><mixed-citation xml:lang="en">Верткин АЛ, Ткачева ОН, Новикова ИМ. Безболевая ишемия и диабетическая автономная нейропатия. Русский медицинский журнал. 2005; 13(20):1036-1038.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Gutterman DD. Silent myocardial ischemia. Circ J. 2009 May;73(5):785-797. Epub 2009 Mar 13.</mixed-citation><mixed-citation xml:lang="en">Gutterman DD. Silent myocardial ischemia. Circ J. 2009 May;73(5):785-797. Epub 2009 Mar 13.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Zellweger MJ. Prognostic significance of silent coronary artery disease in type 2 diabetes. Herz. 2006 May;31(3):240-245.</mixed-citation><mixed-citation xml:lang="en">Zellweger MJ. Prognostic significance of silent coronary artery disease in type 2 diabetes. Herz. 2006 May;31(3):240-245.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Young LH, Wackers FJ, Chyun DA, Davey JA, Barrett EJ, Taillefer R, Heller GV, Iskandrian AE, Wittlin SD, Filipchuk N, Ratner RE, Inzucchi SE; DIAD Investigators. Cardiac outcomes after screening for asymptomatic coronary artery disease in patients with type 2 diabetes: the DIAD study: a randomized controlled trial. JAMA. 2009 Apr 15;301(15):1547-1555.</mixed-citation><mixed-citation xml:lang="en">Young LH, Wackers FJ, Chyun DA, Davey JA, Barrett EJ, Taillefer R, Heller GV, Iskandrian AE, Wittlin SD, Filipchuk N, Ratner RE, Inzucchi SE; DIAD Investigators. Cardiac outcomes after screening for asymptomatic coronary artery disease in patients with type 2 diabetes: the DIAD study: a randomized controlled trial. JAMA. 2009 Apr 15;301(15):1547-1555.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Cohn PF, Fox KM, Daly C. Silent Myocardial Ischemia. Circulation. 2003 Sep 9;108(10):1263-1277.</mixed-citation><mixed-citation xml:lang="en">Cohn PF, Fox KM, Daly C. Silent Myocardial Ischemia. Circulation. 2003 Sep 9;108(10):1263-1277.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Machecourt J, Vanzetto G, Fagret D. Strategy of investigation of coronary artery disease in diabetes: from screening to suspicion of acute coronary syndromes. Arch Mal Coeur Vaiss. 2004 Dec;97 Spec No 3:41-46.</mixed-citation><mixed-citation xml:lang="en">Machecourt J, Vanzetto G, Fagret D. Strategy of investigation of coronary artery disease in diabetes: from screening to suspicion of acute coronary syndromes. Arch Mal Coeur Vaiss. 2004 Dec;97 Spec No 3:41-46.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Оганов РГ, Поздняков ЮМ, Акчурин РС и др. Комитет экспертов ВНОК. Диагностика и лечение стабильной стенокардии. Российские рекомендации (второй пересмотр). Кардиоваскулярная терапия и профилактика. 2008;7(6):5-25.</mixed-citation><mixed-citation xml:lang="en">Оганов РГ, Поздняков ЮМ, Акчурин РС и др. Комитет экспертов ВНОК. Диагностика и лечение стабильной стенокардии. Российские рекомендации (второй пересмотр). Кардиоваскулярная терапия и профилактика. 2008;7(6):5-25.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Executive summary: Standards of medical care in diabetes-- 2010. Diabetes Care. 2010 Jan;33 Suppl 1:S4-10.</mixed-citation><mixed-citation xml:lang="en">Executive summary: Standards of medical care in diabetes-- 2010. Diabetes Care. 2010 Jan;33 Suppl 1:S4-10.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Yildirimtürk O, Kiliçgedik M, Tuğcu A, Aytekin V, Aytekin S. The relationship of microalbuminuria with left ventricular functions and silent myocardial ischemia in asymptomatic patients with type 2 diabetes. Turk Kardiyol Dern Ars. 2009 Mar;37(2):91-97.</mixed-citation><mixed-citation xml:lang="en">Yildirimtürk O, Kiliçgedik M, Tuğcu A, Aytekin V, Aytekin S. The relationship of microalbuminuria with left ventricular functions and silent myocardial ischemia in asymptomatic patients with type 2 diabetes. Turk Kardiyol Dern Ars. 2009 Mar;37(2):91-97.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Gazzaruso C, Solerte SB, De Amici E, Mancini M, Pujia A, Fratino P, Giustina A, Garzaniti A. Association of the metabolic syndrome and insulin resistance with silent myocardial ischemia in patients with type 2 diabetes mellitus. Am J Cardiol. 2006 Jan 15;97(2):236-239. Epub 2005 Dec 1.</mixed-citation><mixed-citation xml:lang="en">Gazzaruso C, Solerte SB, De Amici E, Mancini M, Pujia A, Fratino P, Giustina A, Garzaniti A. Association of the metabolic syndrome and insulin resistance with silent myocardial ischemia in patients with type 2 diabetes mellitus. Am J Cardiol. 2006 Jan 15;97(2):236-239. Epub 2005 Dec 1.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Дедов ИИ, Мельниченко ГА. Клинические рекомендации. Эндокринология. М: ГЭОТАР-Медиа; 2008.</mixed-citation><mixed-citation xml:lang="en">Дедов ИИ, Мельниченко ГА. Клинические рекомендации. Эндокринология. М: ГЭОТАР-Медиа; 2008.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Кишкун АА. Руководство по лабораторным методам диагно- стики. М: ГЭОТАР-Медиа; 2007.</mixed-citation><mixed-citation xml:lang="en">Кишкун АА. Руководство по лабораторным методам диагно- стики. М: ГЭОТАР-Медиа; 2007.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Wallace TM, Levy JC, Matthews DR. Use and abuse of HOMA modeling. Diabetes Care. 2004 Jun;27(6):1487-1495.</mixed-citation><mixed-citation xml:lang="en">Wallace TM, Levy JC, Matthews DR. Use and abuse of HOMA modeling. Diabetes Care. 2004 Jun;27(6):1487-1495.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Ткачева ОН, Зорина СА, Хайбулина ЭТ, Ибраги- мова ЛМ, Полупанова ЮС, Верткин АЛ. Диабетическая автономная нейропатия: распространенность, патогенез, лечение. Русский медицинский журнал. 2005;13(20):1329-1333.</mixed-citation><mixed-citation xml:lang="en">Ткачева ОН, Зорина СА, Хайбулина ЭТ, Ибраги- мова ЛМ, Полупанова ЮС, Верткин АЛ. Диабетическая автономная нейропатия: распространенность, патогенез, лечение. Русский медицинский журнал. 2005;13(20):1329-1333.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Ahmed AH, Shankar K, Eftekhari H, Munir M, Robertson J, Brewer A, Stupin IV, Casscells SW. Silent myocardial ischemia: Current perspectives and future directions. Exp Clin Cardiol. 2007 Winter;12(4):189-196.</mixed-citation><mixed-citation xml:lang="en">Ahmed AH, Shankar K, Eftekhari H, Munir M, Robertson J, Brewer A, Stupin IV, Casscells SW. Silent myocardial ischemia: Current perspectives and future directions. Exp Clin Cardiol. 2007 Winter;12(4):189-196.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Chyun DA, Melkus GD, Katten DM, Price WJ, Davey JA, Grey N, Heller G, Wackers FJ. The association of psychological factors, physical activity, neuropathy, and quality of life in type 2 diabetes. Biol Res Nurs. 2006 Apr;7(4):279-288.</mixed-citation><mixed-citation xml:lang="en">Chyun DA, Melkus GD, Katten DM, Price WJ, Davey JA, Grey N, Heller G, Wackers FJ. The association of psychological factors, physical activity, neuropathy, and quality of life in type 2 diabetes. Biol Res Nurs. 2006 Apr;7(4):279-288.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Vermeulen A, Verdonck L, Kaufman JM. A critical evaluation of simple method for the estimation of free testosterone in serium. J Clin Endocrinol Metab. 1999 Oct;84(10):3666-3672.</mixed-citation><mixed-citation xml:lang="en">Vermeulen A, Verdonck L, Kaufman JM. A critical evaluation of simple method for the estimation of free testosterone in serium. J Clin Endocrinol Metab. 1999 Oct;84(10):3666-3672.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Рыбакова МК, Алехин МН, Митьков ВВ. Практическое руководство по ультразвуковой диагностике. Эхокардиография. М: Издательский дом Видар-М; 2008.</mixed-citation><mixed-citation xml:lang="en">Рыбакова МК, Алехин МН, Митьков ВВ. Практическое руководство по ультразвуковой диагностике. Эхокардиография. М: Издательский дом Видар-М; 2008.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Беленков ЮН, Оганов РГ. Руководство по амбулаторно-поликлинической кардиологии. М: ГЭОТАР-Медиа; 2007.</mixed-citation><mixed-citation xml:lang="en">Беленков ЮН, Оганов РГ. Руководство по амбулаторно-поликлинической кардиологии. М: ГЭОТАР-Медиа; 2007.</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Zweig MH., Campbell G. Receiver-operating characteristic (ROC) plots: a fundamental evaluation tool in clinical medicine. Clin Chem. 1993 Apr;39(4):561-577.</mixed-citation><mixed-citation xml:lang="en">Zweig MH., Campbell G. Receiver-operating characteristic (ROC) plots: a fundamental evaluation tool in clinical medicine. Clin Chem. 1993 Apr;39(4):561-577.</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Davis J, Goadrich M. The Relationship Between Precision-Recall and ROC Curves. Proc. Of 23 International Conference on Machine Learning, Pittsburgh, PA, 2006.</mixed-citation><mixed-citation xml:lang="en">Davis J, Goadrich M. The Relationship Between Precision-Recall and ROC Curves. Proc. Of 23 International Conference on Machine Learning, Pittsburgh, PA, 2006.</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Александров АА. Клинические горизонты кардиопротекции: «кальциевый след» триметазидина. Consilium Medicum. 2005;7(9):757-763.</mixed-citation><mixed-citation xml:lang="en">Александров АА. Клинические горизонты кардиопротекции: «кальциевый след» триметазидина. Consilium Medicum. 2005;7(9):757-763.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
