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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">diaendo</journal-id><journal-title-group><journal-title xml:lang="ru">Сахарный диабет</journal-title><trans-title-group xml:lang="en"><trans-title>Diabetes mellitus</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2072-0351</issn><issn pub-type="epub">2072-0378</issn><publisher><publisher-name>Endocrinology research centre</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14341/2072-0351-5949</article-id><article-id custom-type="elpub" pub-id-type="custom">diaendo-5949</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Articles</subject></subj-group></article-categories><title-group><article-title>Можно ли достигнуть эффективного гликемического контроля сахарного диабета 2 типа: преимущества раннего назначения инсулина</article-title><trans-title-group xml:lang="en"><trans-title>Mozhno li dostignut' effektivnogo glikemicheskogo kontrolya sakharnogo diabeta 2 tipa: preimushchestva rannego naznacheniya insulina</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бирюкова</surname><given-names>Елена Валерьевна</given-names></name><name name-style="western" xml:lang="en"><surname>Biryukova</surname><given-names>Elena Valer'evna</given-names></name></name-alternatives><email xlink:type="simple">info@endojournals.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Московский государственный медико-стоматологический университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Moscow State University of Medicine and Dentistry</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2008</year></pub-date><pub-date pub-type="epub"><day>15</day><month>03</month><year>2008</year></pub-date><volume>11</volume><issue>1</issue><issue-title>№1 (2008)</issue-title><fpage>67</fpage><lpage>72</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Бирюкова Е.В., 2008</copyright-statement><copyright-year>2008</copyright-year><copyright-holder xml:lang="ru">Бирюкова Е.В.</copyright-holder><copyright-holder xml:lang="en">Biryukova E.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.dia-endojournals.ru/jour/article/view/5949">https://www.dia-endojournals.ru/jour/article/view/5949</self-uri><abstract><p>Приоритеты при выборе фармакотерапии СД 2 в настоящее время достаточно обоснованно и точно определены в достигнутом консенсусе ADA и EASD. Прогрессирующее ухудшение метаболического статуса и толерантность к улучшению функции ?-клеток обосновывает более агрессивную тактику лечения СД 2, оправданную уже на начальных стадиях заболевания. Ранняя инсулинотерапия в индивидуально подобранных дозах с использованием современных аналогов человеческого инсулина (Лантус) в виде комбинации с ПСП или монотерапия инсулином ? это лучший путь достижения основных целей лечения, открывающий широкие перспективы: поддержание долгосрочного метаболического контроля и предотвращения или отсрочки сосудистых осложнений. </p></abstract><kwd-group xml:lang="ru"><kwd>сахарный диабет</kwd><kwd>гликемический контроль</kwd><kwd>инсулин</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Федеральная целевая программа «Сахарный диабет»: Методические рекомендации - Москва, 2002</mixed-citation><mixed-citation xml:lang="en">Федеральная целевая программа «Сахарный диабет»: Методические рекомендации - Москва, 2002</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Adeghate E., Schatiner P., Dunn E. 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