diaendoСахарный диабетDiabetes mellitus2072-03512072-0378Endocrinology research centre10.14341/2072-0351-5936diaendo-5936Research ArticleКардиологияCardiologyПроблемы острого инфаркта миокарда у больных сахарным диабетом: эхо МюнхенаProblemy ostrogo infarkta miokarda u bol'nykh sakharnym diabetom: ekho MyunkhenaДедовИван ИвановичDedovIvan Ivanovichdedov@endocrincentr.ruАлександровАндрей АлексеевичAleksandrovAndrey Alexeevichendocar@mail.ruГУ Эндокринологический научный центр РАМН, МоскваРоссияEndocrinology Research Centre, MoscowRussian Federation200815032008111№1 (2008)410Copyright © Дедов И.И., Александров А.А., 20082008Дедов И.И., Александров А.А.Dedov I.I., Aleksandrov A.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.dia-endojournals.ru/jour/article/view/5936

Вопрос о сахароснижающей терапии в остром периоде инфаркта миокарда не исчерпан. Доказательством этого является активный интерес ведущих клиник мира к применению в этот период пероральных сахароснижающих препаратов сульфанилмочевины. Пока выбор наиболее адекватного препарата этой группы для применения в остром периоде инфаркта миокарда еще не сделан, но результаты ?Мюнхена? позволяют уже сейчас широко использовать их в практике лечения больных сахарным диабетом в острый период инфаркта миокарда.

инфаркт миокардасахарный диабетReferencesRyden L et al. Guideline on diabetes, pre-diabetes, and cardiovascular diseases,executive summary. Europ Heart J 2007; 28: 88-136.Ryden L et al. Guideline on diabetes, pre-diabetes, and cardiovascular diseases,executive summary. Europ Heart J 2007; 28: 88-136.Александров А.А., Оганов Р.Г., Бунаева В.Е., Виноградова И.В. Воздействие на метаболизм сердца у больных острым инфарктом миокарда. Кардиология. 1977; 4: 22-29.Александров А.А., Оганов Р.Г., Бунаева В.Е., Виноградова И.В. Воздействие на метаболизм сердца у больных острым инфарктом миокарда. Кардиология. 1977; 4: 22-29.Bartnik M, Ryden L, Ferrari R et al. Euro Heart Survei Investigstors. The prevalence of abnormal glucose regulation in patients with coronary artery disease across Europe. Eur Heart J 2004; 25: 1880-1890.Bartnik M, Ryden L, Ferrari R et al. Euro Heart Survei Investigstors. The prevalence of abnormal glucose regulation in patients with coronary artery disease across Europe. Eur Heart J 2004; 25: 1880-1890.Bartnik M. Studies on prevalence recognition and prognostic implication. Glucose regulation and coronary artery disease. Karolinska Institutet, Stockholm 2005 (ISBN: 91-7140-401-5).Bartnik M. Studies on prevalence recognition and prognostic implication. Glucose regulation and coronary artery disease. Karolinska Institutet, Stockholm 2005 (ISBN: 91-7140-401-5).Malmberg K, Ryden L. Myocardial infarction in patients with diabetes mellitus. Eur Heart J 1988; 9: 256-264.Malmberg K, Ryden L. Myocardial infarction in patients with diabetes mellitus. Eur Heart J 1988; 9: 256-264.Karlson BW, Herlitz J, Hjalmarson A. Prognosis of acute myocardial infarction in diabetic and non-diabetic patients. Diabet Med 1993; 10 (5): 449-454.Karlson BW, Herlitz J, Hjalmarson A. Prognosis of acute myocardial infarction in diabetic and non-diabetic patients. Diabet Med 1993; 10 (5): 449-454.Rytter L, Beck-Nielsen H, Troelsen S. Diabetic patients and myocardial infarction. Acta Endocrinologica 1984; suppl. 262: 83-87.Rytter L, Beck-Nielsen H, Troelsen S. Diabetic patients and myocardial infarction. Acta Endocrinologica 1984; suppl. 262: 83-87.Herlitz J, Malmberg K, Karlsson B et al. Mortality and morbidity during a five year follow-up of diabetics with myocardial infarction. Acta Med Scand 1988; 24: 31-38.Herlitz J, Malmberg K, Karlsson B et al. Mortality and morbidity during a five year follow-up of diabetics with myocardial infarction. Acta Med Scand 1988; 24: 31-38.Ulvenstam G, Aberg A, Bergstrang R et al. Long-term prognosis after myocardial infarction in men with diabetes mellitus. Diabetes 1985; 34: 787-792.Ulvenstam G, Aberg A, Bergstrang R et al. Long-term prognosis after myocardial infarction in men with diabetes mellitus. Diabetes 1985; 34: 787-792.Orlander PR, Goff DC, Morrissey M et al. The relation of diabetes to the severity of acute myocardial infarction and post-myocardial infarction survival in Mexican-Americfns and non-Hispanic whites. The Corpus Christi heart project. Diabetes 1994; 43 (7): 897-902.Orlander PR, Goff DC, Morrissey M et al. The relation of diabetes to the severity of acute myocardial infarction and post-myocardial infarction survival in Mexican-Americfns and non-Hispanic whites. The Corpus Christi heart project. Diabetes 1994; 43 (7): 897-902.Jaffe A, Spadaro J, Schehtmann K et al. Increased congestive heart failure myocardial infarction of modest extent in patients with diabetes mellitus. Am Heart J 1984; 108: 31-37.Jaffe A, Spadaro J, Schehtmann K et al. Increased congestive heart failure myocardial infarction of modest extent in patients with diabetes mellitus. Am Heart J 1984; 108: 31-37.Abbud Z, Shindler D, Wilson A, Kostis J. Effect of diabetes mellitus on short and long term mortality rates of patients with acute myocardial infarction: a statewide study . Am Heart J 1995; 130: 51-58.Abbud Z, Shindler D, Wilson A, Kostis J. Effect of diabetes mellitus on short and long term mortality rates of patients with acute myocardial infarction: a statewide study . Am Heart J 1995; 130: 51-58.Smith J, Marcus F, Serokman R. Prognosis of patients with diabetes mellitus after myocardial infarction. Am J Cardiol 1984; 54: 718-721.Smith J, Marcus F, Serokman R. Prognosis of patients with diabetes mellitus after myocardial infarction. Am J Cardiol 1984; 54: 718-721.Granger CB, Callif RM, Young S et al. Outcome of patients with diabetes mellitus and acute myocardial infarction treated with thrombolytic agents. The thrombolysis and angioplasty in myocardial infarction (TAMI) study group. J Am Coll Cardiol 1993; 21 (4): 920-925.Granger CB, Callif RM, Young S et al. Outcome of patients with diabetes mellitus and acute myocardial infarction treated with thrombolytic agents. The thrombolysis and angioplasty in myocardial infarction (TAMI) study group. J Am Coll Cardiol 1993; 21 (4): 920-925.Singer D, Moulton A, Nathan D. Diabetic myocardial infarction. Interaction of diabetes with other preinfarction risk factors. Diabetes 1989; 38: 350-357.Singer D, Moulton A, Nathan D. Diabetic myocardial infarction. Interaction of diabetes with other preinfarction risk factors. Diabetes 1989; 38: 350-357.Stone P, Muller J, Hartwell T et al. The effect of diabetes mellitus on prognosis and serial left ventricular function after acute myocardial infarction: contribution of both coronary disease and diastolic left ventricular dysfunction to the adverse prognosis. JACC 1989; 14; 49-57.Stone P, Muller J, Hartwell T et al. The effect of diabetes mellitus on prognosis and serial left ventricular function after acute myocardial infarction: contribution of both coronary disease and diastolic left ventricular dysfunction to the adverse prognosis. JACC 1989; 14; 49-57.Savage M, Krolevski A, Kenien G et al. Acute myocardial infarction in diabetes mellitus and significance of congestive heart failure as a prognostic factor. Am J Cardiol 1988; 62: 665-9.Savage M, Krolevski A, Kenien G et al. Acute myocardial infarction in diabetes mellitus and significance of congestive heart failure as a prognostic factor. Am J Cardiol 1988; 62: 665-9.Jacoby R, Nesto R. Acute myocardial infarction in the diabetic patients: pathophysiology, clinical course and prognosis. J Am Coll Cardiol 1992; 20: 736-44.Jacoby R, Nesto R. Acute myocardial infarction in the diabetic patients: pathophysiology, clinical course and prognosis. J Am Coll Cardiol 1992; 20: 736-44.Malgorzata Bartnik, Lars Ryden, Roberto Ferrari, Klas Malmberg, Kalevi Pyoraa, Maarten Simoons, Eberhard Standl, Jordi Soler-Soler, and John Ohrvik on behalf of the Euro Heart Survey Investigators. The prevalence of abnormal glucose regulation in patients with coronary artery disease across Europe: The Euro Heart Survey on diabetes and the heart. Eur Heart J 2004 25: 1880-1890.Malgorzata Bartnik, Lars Ryden, Roberto Ferrari, Klas Malmberg, Kalevi Pyoraa, Maarten Simoons, Eberhard Standl, Jordi Soler-Soler, and John Ohrvik on behalf of the Euro Heart Survey Investigators. The prevalence of abnormal glucose regulation in patients with coronary artery disease across Europe: The Euro Heart Survey on diabetes and the heart. Eur Heart J 2004 25: 1880-1890.Klas Malmberg, Anna Norhammar, Hans Wedel, and Lars Ryd n. Glycometabolic State at Admission: Important Risk Marker of Mortality in Conventionally Treated Patients With Diabetes Mellitus and Acute Myocardial Infarction : Long-Term Results From the Diabetes and Insulin-Glucose Infusion in Acute Myocardial Infarction (DIGAMI) Study. Circulation 1999 99: 2626 - 2632Klas Malmberg, Anna Norhammar, Hans Wedel, and Lars Ryd n. Glycometabolic State at Admission: Important Risk Marker of Mortality in Conventionally Treated Patients With Diabetes Mellitus and Acute Myocardial Infarction : Long-Term Results From the Diabetes and Insulin-Glucose Infusion in Acute Myocardial Infarction (DIGAMI) Study. Circulation 1999 99: 2626 - 2632Rogers W, Segal P, McDaniel H, Mantel J, Russet R, Rackley C. Prospective randomised trial of glucose-insulin-potassium in acute myocardial infarction. Am J Cardiol 1979;43:801-808.Rogers W, Segal P, McDaniel H, Mantel J, Russet R, Rackley C. Prospective randomised trial of glucose-insulin-potassium in acute myocardial infarction. Am J Cardiol 1979;43:801-808.K. Malmberg, L. Ryd n, H. Wedel, K. Birkeland, A. Bootsma, K. Dickstein, S. Efendic, M. Fisher, A. Hamsten, J. Herlitz, P. Hildebrandt, K. MacLeod, M. Laakso, C. Torp-Pedersen, and A. Waldenstr m for the DIGAMI 2 Investigator Intense metabolic control by means of insulin in patients with diabetes mellitus and acute myocardial infarction (DIGAMI 2): effects on mortality and morbidity. Eur Heart J 2005 26: 650-661.K. Malmberg, L. Ryd n, H. Wedel, K. Birkeland, A. Bootsma, K. Dickstein, S. Efendic, M. Fisher, A. Hamsten, J. Herlitz, P. Hildebrandt, K. MacLeod, M. Laakso, C. Torp-Pedersen, and A. Waldenstr m for the DIGAMI 2 Investigator Intense metabolic control by means of insulin in patients with diabetes mellitus and acute myocardial infarction (DIGAMI 2): effects on mortality and morbidity. Eur Heart J 2005 26: 650-661.Brady PA, Al-Suwaidi J, Kopekcy SL, Terzic A. Sulfonylureas and mortality in diabetic patients after myocardial infarction. Circulation 1998; 97: 709-710.Brady PA, Al-Suwaidi J, Kopekcy SL, Terzic A. Sulfonylureas and mortality in diabetic patients after myocardial infarction. Circulation 1998; 97: 709-710.Halkin A, Roth A, Jonas B, Behar S. Sulfonylureas are not associated with increased mortality in diabetics treated with thrombolysis for acute myocardial infarction. J Thromb Thrombolysis 2001; 12: 177-184.Halkin A, Roth A, Jonas B, Behar S. Sulfonylureas are not associated with increased mortality in diabetics treated with thrombolysis for acute myocardial infarction. J Thromb Thrombolysis 2001; 12: 177-184.Klamann A, Sarfert P, Launhardt V et al. Myocardial infarction in diabetic and non-diabetic subjects. Survival and infarct size following therapy with sulfonylureas (glibencklamide). Eur Heart J 2000; 21: 220-229.Klamann A, Sarfert P, Launhardt V et al. Myocardial infarction in diabetic and non-diabetic subjects. Survival and infarct size following therapy with sulfonylureas (glibencklamide). Eur Heart J 2000; 21: 220-229.Aronow WS, Ahn C. Incidence of new coronary events in older persons with diabetes mellitus and prior myocardial infarction treated with sulfonylureas, insulin, metformin, and diet alone. Am J Cardiol 2001; 88: 556-557.Aronow WS, Ahn C. Incidence of new coronary events in older persons with diabetes mellitus and prior myocardial infarction treated with sulfonylureas, insulin, metformin, and diet alone. Am J Cardiol 2001; 88: 556-557.Jollis JG, Simpson RJJr, Cascio WE et al. Relation between sulfonylurea therapy, complications, and outcome for elderly patients with acute myocardial infarction. Am Heart J 1999; 138 (5 Pt 1): S376-380.Jollis JG, Simpson RJJr, Cascio WE et al. Relation between sulfonylurea therapy, complications, and outcome for elderly patients with acute myocardial infarction. Am Heart J 1999; 138 (5 Pt 1): S376-380.Thisted H, Johnsen SP, Rungby J. Sulfonylureas and the risk of myocardial infarction. Metab Clinic Experiment J 2006; 55 (Suppl. 1): S16-S19.Thisted H, Johnsen SP, Rungby J. Sulfonylureas and the risk of myocardial infarction. Metab Clinic Experiment J 2006; 55 (Suppl. 1): S16-S19.Nicolas Danchin et al. Role of previous treatment with sulfonylureas in diabetic patients with acute myocardial infarction: results from a nation wide French registry. Diabetes Metab Res Rev 2005; 21: 143-149.Nicolas Danchin et al. Role of previous treatment with sulfonylureas in diabetic patients with acute myocardial infarction: results from a nation wide French registry. Diabetes Metab Res Rev 2005; 21: 143-149.Gustafsson I et al. Long-term prognosis of diabetic patients with myocardial infarction: relation to antidiabetic treatment regimen. Europe Heart J 2000; 21: 1937-1943.Gustafsson I et al. Long-term prognosis of diabetic patients with myocardial infarction: relation to antidiabetic treatment regimen. Europe Heart J 2000; 21: 1937-1943.

The authors declare that there are no conflicts of interest present.