diaendoСахарный диабетDiabetes mellitus2072-03512072-0378Endocrinology research centre10.14341/2072-0351-5917diaendo-5917Research ArticleСтатьиArticlesВлияние препаратов сульфонилмочевины на сердечно-сосудистую системуVliyanie preparatov sul'fonilmocheviny na serdechno-sosudistuyu sistemuШестаковаМарина ВладимировнаShestakovaMarina Vladimirovna-ФГУ Эндокринологический научный центр Росмедтехнологий, МоскваEndocrinology Research Centre, Moscow200715032007101№1 (2007)5459Copyright © Шестакова М.В., 20072007Шестакова М.В.Shestakova M.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.dia-endojournals.ru/jour/article/view/5917

Исследование UKPDS показало, что хороший контроль гликемии у больных СД 2 может предотвратить сердечно-сосудистые осложнения. Тем не менее оказалось, что существуют различия между разными вариантами противодиабетического лечения в отношении их кардиопротективного действия. Недавние клинические испытания выявили значительные различия между препаратами сульфонилмочевины разных поколений в отношении их влияния на развитие сердечно-сосудистых заболеваний. Защитные свойства препаратов нового поколения, таких как гликлазид МВ, связывают как с их антиатерогенным, антитромботическим и антиоксидантным эффектами, так и с отсутствием влияния на ишемическое прекондиционирование.

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The authors declare that there are no conflicts of interest present.