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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">diaendo</journal-id><journal-title-group><journal-title xml:lang="ru">Сахарный диабет</journal-title><trans-title-group xml:lang="en"><trans-title>Diabetes mellitus</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2072-0351</issn><issn pub-type="epub">2072-0378</issn><publisher><publisher-name>Endocrinology research centre</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14341/2072-0351-5879</article-id><article-id custom-type="elpub" pub-id-type="custom">diaendo-5879</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Articles</subject></subj-group></article-categories><title-group><article-title>Проблемы и перспективы гиполипидемической терапии при сахарном диабете (Сообщение 1)</article-title><trans-title-group xml:lang="en"><trans-title>Problemy i perspektivy gipolipidemicheskoy terapii pri sakharnom diabete (Soobshchenie 1)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дедов</surname><given-names>Иван Иванович</given-names></name><name name-style="western" xml:lang="en"><surname>Dedov</surname><given-names>Ivan Ivanovich</given-names></name></name-alternatives><email xlink:type="simple">-</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Александров</surname><given-names>Андрей Алексеевич</given-names></name><name name-style="western" xml:lang="en"><surname>Aleksandrov</surname><given-names>Andrey Alexeevich</given-names></name></name-alternatives><email xlink:type="simple">-</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Эндокринологический научный центр РАМН, Москва</institution></aff><aff xml:lang="en"><institution>Endocrinology Research Centre, Moscow</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2000</year></pub-date><pub-date pub-type="epub"><day>15</day><month>06</month><year>2000</year></pub-date><volume>3</volume><issue>2</issue><issue-title>№2 (2000)</issue-title><fpage>9</fpage><lpage>12</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Дедов И.И., Александров А.А., 2000</copyright-statement><copyright-year>2000</copyright-year><copyright-holder xml:lang="ru">Дедов И.И., Александров А.А.</copyright-holder><copyright-holder xml:lang="en">Dedov I.I., Aleksandrov A.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.dia-endojournals.ru/jour/article/view/5879">https://www.dia-endojournals.ru/jour/article/view/5879</self-uri><abstract><p>Сердечно-сосудистые заболевания являются основной причиной смерти больных сахарным диабетом (СД) старше 30 лет. В настоящее время каждый четвертый больной ишемической болезнью сердца (ИБС) страдает СД; каждый пятый больной, оперируемый по поводу коронарной болезни сердца, - это тоже больной СД. Быстрое развитие осложнений ИБС и высокая летальность при этом у больных СД  свидетельствуют о необходимости ранней, активной и настойчивой профилактики коронарного атеросклероза. В настоящее время отмечается нарастание данных, подтверждающих независимую роль диабетической дислипидемии в целом и каждого из ее компонентов в отдельности в развитии ИБС при СД. При первичной профилактике основной целью гиполипидемичеких мероприятий является снижение концентрации холестерина ЛПНП ниже уровня 130 мг/дл. Достижение более низкого уровня холестерина ЛПНП (менее 100 мг/дл) рекомендуется при первичной профилактике ИБС у больных с наличием одного или более факторов риска ИБС. Целями второго уровня при первичной профилактике ИБС у больных СД являются повышение концентрации холестерина ЛПНП более 35 мг/дл и снижение концентрации триглицеридов менее 200 мг/дл. Основной целью вторичной профилактики ИБС у больных СД является снижение концентрации холестерина ЛПНП ниже 100 мг/дл. Целями второго уровня вторичной профилактики ИБС при СД являются повышение концентрации холестерина ЛПВП более 35мг/дл и снижение уровня триглицеридов менее 200 мг/дл. Сформулированные в настоящее время цели гиполипидемической терапии для больных сахарным диабетом, являясь обоснованным руководством к практической деятельности.</p></abstract><kwd-group xml:lang="ru"><kwd>сахарный диабет</kwd><kwd>гиполипидемическая терапия</kwd><kwd>ИБС</kwd><kwd>дислипидемия</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">American Diabetes Association. 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