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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">diaendo</journal-id><journal-title-group><journal-title xml:lang="ru">Сахарный диабет</journal-title><trans-title-group xml:lang="en"><trans-title>Diabetes mellitus</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2072-0351</issn><issn pub-type="epub">2072-0378</issn><publisher><publisher-name>Endocrinology research centre</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14341/2072-0351-5827</article-id><article-id custom-type="elpub" pub-id-type="custom">diaendo-5827</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Articles</subject></subj-group></article-categories><title-group><article-title>Ингибиторы АПФ как фактор риска гипогликемии</article-title><trans-title-group xml:lang="en"><trans-title>ACE inhibitors as a risk factor for hypoglycemia</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Александров</surname><given-names>Андрей Алексеевич</given-names></name><name name-style="western" xml:lang="en"><surname>Aleksandrov</surname><given-names>Andrey Alexeevich</given-names></name></name-alternatives><email xlink:type="simple">endocar@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кухаренко</surname><given-names>Светлана Семеновна</given-names></name><name name-style="western" xml:lang="en"><surname>Kukharenko</surname><given-names>Svetlana Semenovna</given-names></name></name-alternatives><email xlink:type="simple">-</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кулиева</surname><given-names>Мария Николаевна</given-names></name><name name-style="western" xml:lang="en"><surname>Kulieva</surname><given-names>Maria Nikolaevna</given-names></name></name-alternatives><email xlink:type="simple">-</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шацкая</surname><given-names>Олеся Михайловна</given-names></name><name name-style="western" xml:lang="en"><surname>Shatskaya</surname><given-names>Olesya Mikhailovna</given-names></name></name-alternatives><email xlink:type="simple">-</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шацкая</surname><given-names>Ольга Александровна</given-names></name><name name-style="western" xml:lang="en"><surname>Shatskaya</surname><given-names>Olga Alexandrovna</given-names></name></name-alternatives><email xlink:type="simple">-</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мартьянова</surname><given-names>Ирина Ивановна</given-names></name><name name-style="western" xml:lang="en"><surname>Mart'yanova</surname><given-names>Irina Ivanovna</given-names></name></name-alternatives><email xlink:type="simple">-</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дроздова</surname><given-names>Елена Николаевна</given-names></name><name name-style="western" xml:lang="en"><surname>Drozdova</surname><given-names>Elena Nikolaevna</given-names></name></name-alternatives><email xlink:type="simple">-</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кудряшова</surname><given-names>Александра Леонидовна</given-names></name><name name-style="western" xml:lang="en"><surname>Kudryashova</surname><given-names>Alexandra Leonidovna</given-names></name></name-alternatives><email xlink:type="simple">-</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ Эндокринологический научный центр, Москва</institution></aff><aff xml:lang="en"><institution>Endocrinology Research Centre, Moscow</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2011</year></pub-date><pub-date pub-type="epub"><day>15</day><month>12</month><year>2011</year></pub-date><volume>14</volume><issue>4</issue><issue-title>№4 (2011)</issue-title><fpage>107</fpage><lpage>110</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Александров А.А., Кухаренко С.С., Кулиева М.Н., Шацкая О.М., Шацкая О.А., Мартьянова И.И., Дроздова Е.Н., Кудряшова А.Л., 2011</copyright-statement><copyright-year>2011</copyright-year><copyright-holder xml:lang="ru">Александров А.А., Кухаренко С.С., Кулиева М.Н., Шацкая О.М., Шацкая О.А., Мартьянова И.И., Дроздова Е.Н., Кудряшова А.Л.</copyright-holder><copyright-holder xml:lang="en">Aleksandrov A.A., Kukharenko S.S., Kulieva M.N., Shatskaya O.M., Shatskaya O.A., Mart'yanova I.I., Drozdova E.N., Kudryashova A.L.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.dia-endojournals.ru/jour/article/view/5827">https://www.dia-endojournals.ru/jour/article/view/5827</self-uri><abstract><p>В настоящее время доказано, что гипогликемия является независимым фактором риска сердечно-сосудистых событий. Назначениепрепаратов из группы ингибиторов ангиотензинпревращающего фермента (иАПФ) улучшает чувствительность тканей к инсулинуи может вызывать гипогликемические состояния. На данном клиническом примере демонстрируется необходимость тщательного кон-троля гликемии в начальный период назначения иАПФ больным сахарным диабетом.</p></abstract><trans-abstract xml:lang="en"><p>It is known that hypoglycemia is associated with an increased risk of cardiovascular adverse events including death. ACE-inhibitors, when taken withantidiabetic drugs, can cause hypoglycemic episodes by improving insulin sensitivity. This clinical case illustrates the necessity to monitor plasmaglucose in the early phase of the treatment by the ACE-inhibitors in diabetic patients.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>сахарный диабет</kwd><kwd>гипогликемия</kwd><kwd>ингибиторы АПФ</kwd></kwd-group><kwd-group xml:lang="en"><kwd>diabetes mellitus</kwd><kwd>hypoglycemia</kwd><kwd>ACE inhibitors</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Desouza C., Bolli G., Fonseca V. Hypoglycemia, Diabetes, and Cardiovascular Events // Diabetes Care. - 2010. - Vol. 33. - P. 1389-1394.</mixed-citation><mixed-citation xml:lang="en">Desouza C., Bolli G., Fonseca V. 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