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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">diaendo</journal-id><journal-title-group><journal-title xml:lang="ru">Сахарный диабет</journal-title><trans-title-group xml:lang="en"><trans-title>Diabetes mellitus</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2072-0351</issn><issn pub-type="epub">2072-0378</issn><publisher><publisher-name>Endocrinology research centre</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14341/2072-0351-5811</article-id><article-id custom-type="elpub" pub-id-type="custom">diaendo-5811</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Articles</subject></subj-group></article-categories><title-group><article-title>Взаимосвязь ингибитора активатора плазминогена и свободных жирных кислот с инсулинорезистентностью у больных инфарктом миокарда</article-title><trans-title-group xml:lang="en"><trans-title>Role of plasminogen activator inhibitor and free fatty acids in diagnosis of insulin resistance in patients with myocardial infarction</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Груздева</surname><given-names>Ольга Викторовна</given-names></name><name name-style="western" xml:lang="en"><surname>Gruzdeva</surname><given-names>Olga Viktorovna</given-names></name></name-alternatives><email xlink:type="simple">-</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Барбараш</surname><given-names>Ольга Леонидовна</given-names></name><name name-style="western" xml:lang="en"><surname>Barbarash</surname><given-names>Olga Leonidovna</given-names></name></name-alternatives><email xlink:type="simple">-</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Акбашева</surname><given-names>Ольга Евгеньевна</given-names></name><name name-style="western" xml:lang="en"><surname>Akbasheva</surname><given-names>Olga Evgen'evna</given-names></name></name-alternatives><email xlink:type="simple">-</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Федорова</surname><given-names>Татьяна Сергеевна</given-names></name><name name-style="western" xml:lang="en"><surname>Fedorova</surname><given-names>Tatiana Sergeevna</given-names></name></name-alternatives><email xlink:type="simple">-</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Паличева</surname><given-names>Елена Ивановна</given-names></name><name name-style="western" xml:lang="en"><surname>Palicheva</surname><given-names>Elena Ivanovna</given-names></name></name-alternatives><email xlink:type="simple">-</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кашталап</surname><given-names>Vasiliy Васильевич</given-names></name><name name-style="western" xml:lang="en"><surname>Kashtalap</surname><given-names>Vasil'evich</given-names></name></name-alternatives><email xlink:type="simple">-</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дылева</surname><given-names>Юлия Александровна</given-names></name><name name-style="western" xml:lang="en"><surname>Dyleva</surname><given-names>Yulia Alexandrovna</given-names></name></name-alternatives><email xlink:type="simple">-</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Силонова</surname><given-names>Анна Александровна</given-names></name><name name-style="western" xml:lang="en"><surname>Silonova</surname><given-names>Anna Alexandrovna</given-names></name></name-alternatives><email xlink:type="simple">-</email><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сионина</surname><given-names>Екатерина Владимировна</given-names></name><name name-style="western" xml:lang="en"><surname>Sionina</surname><given-names>Ekaterina Vladimirovna</given-names></name></name-alternatives><email xlink:type="simple">-</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Учасова</surname><given-names>Евгения Геннадьевна</given-names></name><name name-style="western" xml:lang="en"><surname>Uchasova</surname><given-names>Evgenia Gennad'evna</given-names></name></name-alternatives><email xlink:type="simple">-</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>НИИ Комплексных проблем сердечно-сосудистых заболеваний, Кемерово</institution></aff><aff xml:lang="en"><institution>Research Institute of complex problems of cardiovascular disease RAMS, Kemerovo</institution></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>НИИ Комплексных проблем сердечно-сосудистых заболеваний, Кемерово; ГБОУ Кемеровская государственная медицинская академия, Кемерово</institution></aff><aff xml:lang="en"><institution>Research Institute of complex problems of cardiovascular disease RAMS, Kemerovo; Kemerovskaya State Medical Academy, Kemerovo</institution></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ГБОУ Сибирский государственный медицинский университет, Томск</institution></aff><aff xml:lang="en"><institution>Siberian State Medical University, Tomsk</institution></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>ГБОУ Кемеровская государственная медицинская академия, Кемерово</institution></aff><aff xml:lang="en"><institution>Kemerovskaya State Medical Academy, Kemerovo</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2011</year></pub-date><pub-date pub-type="epub"><day>15</day><month>12</month><year>2011</year></pub-date><volume>14</volume><issue>4</issue><issue-title>№4 (2011)</issue-title><fpage>18</fpage><lpage>23</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Груздева О.В., Барбараш О.Л., Акбашева О.Е., Федорова Т.С., Паличева Е.И., Кашталап V.В., Дылева Ю.А., Силонова А.А., Сионина Е.В., Учасова Е.Г., 2011</copyright-statement><copyright-year>2011</copyright-year><copyright-holder xml:lang="ru">Груздева О.В., Барбараш О.Л., Акбашева О.Е., Федорова Т.С., Паличева Е.И., Кашталап V.В., Дылева Ю.А., Силонова А.А., Сионина Е.В., Учасова Е.Г.</copyright-holder><copyright-holder xml:lang="en">Gruzdeva O.V., Barbarash O.L., Akbasheva O.E., Fedorova T.S., Palicheva E.I., Кашталап V.В., Dyleva Y.A., Silonova A.A., Sionina E.V., Uchasova E.G.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.dia-endojournals.ru/jour/article/view/5811">https://www.dia-endojournals.ru/jour/article/view/5811</self-uri><abstract/><trans-abstract xml:lang="en"/><kwd-group xml:lang="ru"><kwd>сахарный диабет 2 типа</kwd><kwd>инфаркт миокарда</kwd><kwd>инсулинорезистентность</kwd><kwd>свободные жирные кислоты</kwd><kwd>ингибитор ак- тиватора плазминогена</kwd></kwd-group><kwd-group xml:lang="en"><kwd>type 2 diabetes mellitus</kwd><kwd>myocardial infarction</kwd><kwd>insulin resistance</kwd><kwd>free fatty acids</kwd><kwd>plasminogen activator inhibitor type-1</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Collet J.P., Montalescot G., Vicaut E. Acute release of plasminogen activator inhibitor-1 in ST-segment elevation myocardial infarction predicts mortality // Circulation. - 2003. - Vol. 108. - P. 391-394.</mixed-citation><mixed-citation xml:lang="en">Collet J.P., Montalescot G., Vicaut E. Acute release of plasminogen activator inhibitor-1 in ST-segment elevation myocardial infarction predicts mortality // Circulation. - 2003. - Vol. 108. - P. 391-394.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Ishihara M., Kojima S., Sakamoto T. Acute hyperglycemia is associated with adverse outcome after acute myocardial infarction in the coronary intervention era // J. Am. Heart. - 2005. - Vol. 150. - P. 814-820.</mixed-citation><mixed-citation xml:lang="en">Ishihara M., Kojima S., Sakamoto T. Acute hyperglycemia is associated with adverse outcome after acute myocardial infarction in the coronary intervention era // J. Am. Heart. - 2005. - Vol. 150. - P. 814-820.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Alessi M., Juhan-Vague I. PAI-1 and the Metabolic Syndrome // Arteriosclerosis, Thrombosis, and Vascular Biology. - 2006. - Vol. 26. - P. 2200-2207.</mixed-citation><mixed-citation xml:lang="en">Alessi M., Juhan-Vague I. PAI-1 and the Metabolic Syndrome // Arteriosclerosis, Thrombosis, and Vascular Biology. - 2006. - Vol. 26. - P. 2200-2207.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Lopez-Alemany R., Redondo J. M., Nagamine Y., Munoz-Canoves P. Plasminogen activator inhibitor type-1 inhibits insulin signaling by competing with avb3 integrin for vitronectin binding // J. Eur. Biochem. - 2003. - Vol. 270. - P. 814-821.</mixed-citation><mixed-citation xml:lang="en">Lopez-Alemany R., Redondo J. M., Nagamine Y., Munoz-Canoves P. Plasminogen activator inhibitor type-1 inhibits insulin signaling by competing with avb3 integrin for vitronectin binding // J. Eur. Biochem. - 2003. - Vol. 270. - P. 814-821.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Campbell I.W. The role of metformin and pioglitazone in early combination treatment of type 2 diabetes mellitus // Brit. J. of Diabetes &amp;amp; Vasc. Dis. - 2006. - Vol. 6. - P. 207-215.</mixed-citation><mixed-citation xml:lang="en">Campbell I.W. The role of metformin and pioglitazone in early combination treatment of type 2 diabetes mellitus // Brit. J. of Diabetes &amp;amp; Vasc. Dis. - 2006. - Vol. 6. - P. 207-215.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Cefalu W.T. Insulin resistance: cellular and clinical concepts // Exp. Biol. Med. - 2001. - Vol. 226. - P. 13-26.</mixed-citation><mixed-citation xml:lang="en">Cefalu W.T. Insulin resistance: cellular and clinical concepts // Exp. Biol. Med. - 2001. - Vol. 226. - P. 13-26.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Huxley R., Barzi F., Woodward M. Excess risk of fatal coronary heart disease associated with diabetes in men and women: meta-analysis of 37 prospective cohort studies // B.M.J. - 2006. - Vol. 332. - P. 73-78.</mixed-citation><mixed-citation xml:lang="en">Huxley R., Barzi F., Woodward M. Excess risk of fatal coronary heart disease associated with diabetes in men and women: meta-analysis of 37 prospective cohort studies // B.M.J. - 2006. - Vol. 332. - P. 73-78.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Leclercq I.A., Da Silva Morais A., Schroyen B., Van Hul N., Geerts A. Insulin resistance in hepatocytes and sinusoidal liver cells: mechanisms and consequences // J. Hepatol. - 2007. - Vol. 47. - № 1. - P. 142-156.</mixed-citation><mixed-citation xml:lang="en">Leclercq I.A., Da Silva Morais A., Schroyen B., Van Hul N., Geerts A. Insulin resistance in hepatocytes and sinusoidal liver cells: mechanisms and consequences // J. Hepatol. - 2007. - Vol. 47. - № 1. - P. 142-156.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Lopaschuk G.D., Ussher J.R., Folmes C.D.L., Jaswal J.S., Stanley W.C. Myocardial Fatty Acid Metabolism in Health and Disease // Physiol. Rev. - 2010. - Vol. 90. - P. 207-258.</mixed-citation><mixed-citation xml:lang="en">Lopaschuk G.D., Ussher J.R., Folmes C.D.L., Jaswal J.S., Stanley W.C. Myocardial Fatty Acid Metabolism in Health and Disease // Physiol. Rev. - 2010. - Vol. 90. - P. 207-258.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Katz A., Nambi S.S., Mather K., Baron A.D., Follmann D.A., Sullivan G., Quon M.L. Quantitative insulin sensitivity check index: a simple, accurate method for assessing insulin sensitivity in humans // J. Clin. Endocrinol. Metab. - 2000. - Vol. 85. - P. 2402-2410.</mixed-citation><mixed-citation xml:lang="en">Katz A., Nambi S.S., Mather K., Baron A.D., Follmann D.A., Sullivan G., Quon M.L. Quantitative insulin sensitivity check index: a simple, accurate method for assessing insulin sensitivity in humans // J. Clin. Endocrinol. Metab. - 2000. - Vol. 85. - P. 2402-2410.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Juhan-Vague I., Morange P.E., Frere C., Aillaud M.F., Alessi M.C., Hawe E., Boquist S., Tornvall P., Yudkin J.S., Tremoli L., Margaglione M., Di Minno G., Hamsten A., Humphries S.E. The Plasminogen Activator Inhibitor-1 -675 4G/5G genotype influences the risk of Myocardial Infarction associated with elevated plasma proinsulin/insulin levels in men from Europe // J. Thromb. Haemost. - 2003. - Vol. 1. - P. 2322-2329.</mixed-citation><mixed-citation xml:lang="en">Juhan-Vague I., Morange P.E., Frere C., Aillaud M.F., Alessi M.C., Hawe E., Boquist S., Tornvall P., Yudkin J.S., Tremoli L., Margaglione M., Di Minno G., Hamsten A., Humphries S.E. The Plasminogen Activator Inhibitor-1 -675 4G/5G genotype influences the risk of Myocardial Infarction associated with elevated plasma proinsulin/insulin levels in men from Europe // J. Thromb. Haemost. - 2003. - Vol. 1. - P. 2322-2329.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Liang X., Kanjanabuch T., Mao S.L., Hao Chuan-Ming, Tang Yi-Wei, Declerck P.J., Hasty A.H., Wasserman D.H., Fogo A.B., Ma Li-Jun Plasminogen activator inhibitor-1 modulates adipocyte differentiation // J. Physiol. Endocrinol. Metab. - 2006. - Vol. 290. - P. 10-113.</mixed-citation><mixed-citation xml:lang="en">Liang X., Kanjanabuch T., Mao S.L., Hao Chuan-Ming, Tang Yi-Wei, Declerck P.J., Hasty A.H., Wasserman D.H., Fogo A.B., Ma Li-Jun Plasminogen activator inhibitor-1 modulates adipocyte differentiation // J. Physiol. Endocrinol. Metab. - 2006. - Vol. 290. - P. 10-113.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
