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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">diaendo</journal-id><journal-title-group><journal-title xml:lang="ru">Сахарный диабет</journal-title><trans-title-group xml:lang="en"><trans-title>Diabetes mellitus</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2072-0351</issn><issn pub-type="epub">2072-0378</issn><publisher><publisher-name>Endocrinology research centre</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14341/2072-0351-5780</article-id><article-id custom-type="elpub" pub-id-type="custom">diaendo-5780</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Articles</subject></subj-group></article-categories><title-group><article-title>Оценка клинического применения Лантуса (инсулина гларгин) в практике работы эндокринологической службы Москвы</article-title><trans-title-group xml:lang="en"><trans-title>Otsenka klinicheskogo primeneniya Lantusa (insulina glargin) v praktike raboty endokrinologicheskoy sluzhby Moskvy</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Анциферов</surname><given-names>Михаил Борисович</given-names></name><name name-style="western" xml:lang="en"><surname>Antsiferov</surname><given-names>Mikhail Borisovich</given-names></name></name-alternatives><email xlink:type="simple">-</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дорофеева</surname><given-names>Л Г</given-names></name><name name-style="western" xml:lang="en"><surname>Dorofeeva</surname><given-names>L G</given-names></name></name-alternatives><email xlink:type="simple">-</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>Эндокринологический диспансер Департамента здравоохранения г. Москвы</institution></aff><pub-date pub-type="collection"><year>2005</year></pub-date><pub-date pub-type="epub"><day>15</day><month>06</month><year>2005</year></pub-date><volume>8</volume><issue>2</issue><issue-title>№2 (2005)</issue-title><fpage>36</fpage><lpage>41</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Анциферов М.Б., Дорофеева Л.Г., 2005</copyright-statement><copyright-year>2005</copyright-year><copyright-holder xml:lang="ru">Анциферов М.Б., Дорофеева Л.Г.</copyright-holder><copyright-holder xml:lang="en">Antsiferov M.B., Dorofeeva L.G.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.dia-endojournals.ru/jour/article/view/5780">https://www.dia-endojournals.ru/jour/article/view/5780</self-uri><abstract><p>Несмотря на результаты DCCT и UKPDS , доказавшие необходимость адекватного гликемического контроля, большинство пациентов с СД 1 и 2 типа находятся в состоянии суб- и декомпенсации углеводного обмена. Внедрение в клиническую практику инсулина гларгин, имеющего по сравнению с НПХ-инсулином беспиковый профиль действия, более длительный период действия и простой алгоритм титрования дозы, возможно , позволит преодолеть барьеры, препятствующие достижению компенсации углеводного обмена у пациентов с СД 1 и 2 типа не только в условиях клинического исследования , но и в реальной клинической практике.</p></abstract><kwd-group xml:lang="ru"><kwd>инсулин гларгин</kwd><kwd>Лантус</kwd><kwd>сахарный диабет</kwd><kwd>эндокринологическая служба</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Fritsche et al. Glimepiride combined with morning insulin glargine, bedtime NPH insulin, or bedtime insulin glargine in patients with type 2 diabetes mellitus. A randomized control trial. Ann Intern Med 2003, 138: 952-959.</mixed-citation><mixed-citation xml:lang="en">Fritsche et al. 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