diaendoСахарный диабетDiabetes mellitus2072-03512072-0378Endocrinology research centre10.14341/2072-0351-5712diaendo-5712Research ArticleСтатьиArticlesНовые стратегии инсулинотерапии - путь к эффективному гликемическому контролю сахарного диабета 2 типаNew strategies of insulin therapy - a way to effective glycemic control of type 2 diabetes mellitusБирюковаЕлена ВалерьевнаBiryukovaElena Valer'evnalena@obsudim.ruГОУ ВПО Московский государственный медико-стоматологический университет, МоскваMoscow State Medico-Stomatological University, Moscow200915122009124№4 (2009)9092Copyright © Бирюкова Е.В., 20092009Бирюкова Е.В.Biryukova E.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.dia-endojournals.ru/jour/article/view/5712

Один из способов улучшения контроля гликемии - внедрение в клиническую практику современных стратегий интенсификации саха-роснижающей терапии с использованием инсулинов, обладающих улучшенными фармакокинетическими и фармакодинамическими свой-ствами. Приводятся данные международных исследований (OPAL, LACE, GINGER), подтверждающих эффективность стратегийинсулинотерапии ?Базал?, ?Базал-плюс?, что позволяет достичь контроля гликемии у большинства пациентов с сахарным диабетом2 типа без повышения риска гипогликемических состояний и потенциально снизить риск развития и прогрессирования сосудистых ослож-нений.

This paper focuses on the approaches to target glycemic control in patients with type 2 diabetes mellitus. It is emphasized that timely onset of insulintherapy enhances glycemic control and reduces the risk of vascular complications. One way to achieve this goal is to use modern strategies of intensivehypoglycemic therapy with insulins having improved pharmacokinetic and pharmakodynamic properties, e.g. glargine (Lantus) and glulysine (Apidra).Results of international clinical studies confirm effi-ciency of basal and basal-plus insulin strategies allowing to achieve glycemic control in type 2diabetes without heightening the risk of hypoglycemia, development and progression of vascular complications.

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The authors declare that there are no conflicts of interest present.