diaendoСахарный диабетDiabetes mellitus2072-03512072-0378Endocrinology research centre10.14341/2072-0351-5701diaendo-5701Research ArticleСтатьиArticlesАктуальные проблемы компенсации сахарного диабета при беременностиTopical problems of diabetes treatment during pregnancyДемидоваИрина ЮрьевнаDemidovaIrina Yur'evna-АрбатскаяНаталья ЮрьевнаArbatskayaNatalya Yur'evnanarbatskaya@yandex.ruМельниковаЕлена ПетровнаMel'nikovaElena Petrovna-ГОУ ВПО Российский государственный медицинский университет, МоскваRussian State Medical University, MoscowГОУ ВПО Российский государственный медицинский университет, Москва; Городская клиническая больница №1 им. Н.И. Пирогова, МоскваRussian State Medical University, Moscow; N.I. Pirogov City Clinical Hospital, Moscow200915122009124№4 (2009)3236Copyright © Демидова И.Ю., Арбатская Н.Ю., Мельникова Е.П., 20092009Демидова И.Ю., Арбатская Н.Ю., Мельникова Е.П.Demidova I.Y., Arbatskaya N.Y., Mel'nikova E.P.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.dia-endojournals.ru/jour/article/view/5701

Рассмотрены основные причины декомпенсации сахарного диабета (СД) во время беременности: метаболические и гормональные из-менения, влияющие на изменение потребности в инсулине на разных сроках беременности, вариабельность гликемии в связи с особен-ностями фармакокинетики и фармакодинамики препаратов инсулина. Представлены современные данные о целевых значенияхгликемии у беременных с СД, о частоте самоконтроля гликемии, принципах интенсифицированной инсулинотерапии. Обсуждаютсяпреимущества постоянной подкожной инфузии инсулина в обеспечении стабильной компенсации углеводного обмена во время беремен-ности.

The main causes behind decompensation of diabetes mellitus (DM) in pregnant women are consid-ered, such as metabolic and hormonal disturbancesinfluencing insulin requirement in different periods of pregnancy and variability of glycemia related to pharmacokinetic and pharmacodynamicproperties of insu-lin preparations. Recommended target levels of glycemia in pregnant women with DM are cited. The fre-quencyof self-monitoring blood glucose and principles of intensive insulin therapy are discussed. Advan-tages of continuous subcutaneous insulin infusionand its role in the maintenance of stable control of car-bohydrate metabolism during pregnancy are discussed.

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The authors declare that there are no conflicts of interest present.