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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">diaendo</journal-id><journal-title-group><journal-title xml:lang="ru">Сахарный диабет</journal-title><trans-title-group xml:lang="en"><trans-title>Diabetes mellitus</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2072-0351</issn><issn pub-type="epub">2072-0378</issn><publisher><publisher-name>Endocrinology research centre</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14341/2072-0351-5685</article-id><article-id custom-type="elpub" pub-id-type="custom">diaendo-5685</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Articles</subject></subj-group></article-categories><title-group><article-title>Базальная инсулинотерапия у пациентов с сахарным диабетом 2 типа с неудовлетворительным контролем гликемиина пероральной сахароснижающей терапии: результаты прямого сравнительного исследования аналогов инсулина Лантус и Левемир</article-title><trans-title-group xml:lang="en"><trans-title>Basal insulin therapy in patients with type 2 diabetes mellitus and poor control of glycemia by oral hypoglycemic agents: results of direct comparative study of insulin analogs Lantus and Levemir</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Залевская</surname><given-names>Алсу Гафуровна</given-names></name><name name-style="western" xml:lang="en"><surname>Zalevskaya</surname><given-names>Alsu Gafurovna</given-names></name></name-alternatives><email xlink:type="simple">-</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Вербовая</surname><given-names>Нелли Ильинична</given-names></name><name name-style="western" xml:lang="en"><surname>Verbovaya</surname><given-names>Nelli Il'inichna</given-names></name></name-alternatives><email xlink:type="simple">-</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Родионова</surname><given-names>Татьяна Игоревна</given-names></name><name name-style="western" xml:lang="en"><surname>Rodionova</surname><given-names>Tatiana Igorevna</given-names></name></name-alternatives><email xlink:type="simple">-</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Викулова</surname><given-names>Ольга Константиновна</given-names></name><name name-style="western" xml:lang="en"><surname>Vikulova</surname><given-names>Olga Konstantinovna</given-names></name></name-alternatives><email xlink:type="simple">nephro@endocrincentr.ru</email><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шестакова</surname><given-names>Марина Владимировна</given-names></name><name name-style="western" xml:lang="en"><surname>Shestakova</surname><given-names>Marina Vladimirovna</given-names></name></name-alternatives><email xlink:type="simple">-</email><xref ref-type="aff" rid="aff-4"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГОУ ВПО Санкт-Петербургский медицинский университет им. И.П. Павлова, городская многопрофильная больница № 2, Санкт-Петербург</institution></aff><aff xml:lang="en"><institution>I.P. Pavlov Sankt-Peterburg Medical University, City multi-field hospital № 2, Sankt-Peterburg</institution></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ООО «Центр Диабет», Самара</institution></aff><aff xml:lang="en"><institution>Samara State Medical University, Diabet Centre, Samara</institution></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ГОУ ВПО Саратовский государственный медицинский университет им. В.И. Разумовского, Саратов</institution></aff><aff xml:lang="en"><institution>V.I. Razumovsky State Medical University, Saratov</institution></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>ФГУ Эндокринологический научный центр, Москва</institution></aff><aff xml:lang="en"><institution>Endocrinology Research Centre, Moscow</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2010</year></pub-date><pub-date pub-type="epub"><day>15</day><month>06</month><year>2010</year></pub-date><volume>13</volume><issue>2</issue><issue-title>№2 (2010)</issue-title><fpage>106</fpage><lpage>112</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Залевская А.Г., Вербовая Н.И., Родионова Т.И., Викулова О.К., Шестакова М.В., 2010</copyright-statement><copyright-year>2010</copyright-year><copyright-holder xml:lang="ru">Залевская А.Г., Вербовая Н.И., Родионова Т.И., Викулова О.К., Шестакова М.В.</copyright-holder><copyright-holder xml:lang="en">Zalevskaya A.G., Verbovaya N.I., Rodionova T.I., Vikulova O.K., Shestakova M.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.dia-endojournals.ru/jour/article/view/5685">https://www.dia-endojournals.ru/jour/article/view/5685</self-uri><abstract/><trans-abstract xml:lang="en"/><kwd-group xml:lang="ru"><kwd>сахарный диабет 2 типа</kwd><kwd>базальная инсулинотерапия</kwd><kwd>аналоги инсулина человека гларгин и детемир</kwd><kwd>прямое сравни- тельное исследование</kwd></kwd-group><kwd-group xml:lang="en"><kwd>pe 2 diabetes mellitus</kwd><kwd>basal insulin therapy</kwd><kwd>insulin analogs glargin and detemir</kwd><kwd>direct comparative study</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Koro C.E., Bowlin S.J., Bourgeois N., Fedder D.O. Glycemic control from 1988 to 2000 among U.S. adults diagnosed with type 2 diabetes: a preliminary report // Diabetes Care. - 2004. - 27. - P. 17-20.</mixed-citation><mixed-citation xml:lang="en">Koro C.E., Bowlin S.J., Bourgeois N., Fedder D.O. Glycemic control from 1988 to 2000 among U.S. adults diagnosed with type 2 diabetes: a preliminary report // Diabetes Care. - 2004. - 27. - P. 17-20.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Saydah S.H., Fradkin J., Cowie C.C. Poor control of risk factors for vascular disease among adults with previously diagnosed diabetes // JAMA. - 2004. - 291. - Р. 335-342.</mixed-citation><mixed-citation xml:lang="en">Saydah S.H., Fradkin J., Cowie C.C. Poor control of risk factors for vascular disease among adults with previously diagnosed diabetes // JAMA. - 2004. - 291. - Р. 335-342.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Turner R.C., Cull C.A., Frighi V., Holman R.R. UK Prospective Diabetes Study (UKPDS) Group. Glycemic control with diet, sulfonylurea, metformin, or insulin in patients with type 2 diabetes mellitus: prospective requirement for multiple therapies (UKPDS 49) // JAMA. - 1999. - 281. - Р. 2005-2012.</mixed-citation><mixed-citation xml:lang="en">Turner R.C., Cull C.A., Frighi V., Holman R.R. UK Prospective Diabetes Study (UKPDS) Group. Glycemic control with diet, sulfonylurea, metformin, or insulin in patients with type 2 diabetes mellitus: prospective requirement for multiple therapies (UKPDS 49) // JAMA. - 1999. - 281. - Р. 2005-2012.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Nathan D.M., Buse J.B., Davidson M.B. et al. Medical management of hyperglycemia in type 2 diabetes: a consensus algorithm for the initiation and adjustment of therapy. A consensus statement of the American Diabetes Association and the European Association of the study of diabetes // Diabetes care. - 2008. - 31. - Р. 1-11.</mixed-citation><mixed-citation xml:lang="en">Nathan D.M., Buse J.B., Davidson M.B. et al. Medical management of hyperglycemia in type 2 diabetes: a consensus algorithm for the initiation and adjustment of therapy. A consensus statement of the American Diabetes Association and the European Association of the study of diabetes // Diabetes care. - 2008. - 31. - Р. 1-11.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">American Diabetes Association. Standards of medical care in diabetes - 2008 // Diabetes care. - 2008. - 31(suppl 1). - S12-S54.</mixed-citation><mixed-citation xml:lang="en">American Diabetes Association. Standards of medical care in diabetes - 2008 // Diabetes care. - 2008. - 31(suppl 1). - S12-S54.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Guideline for management of postmeal glucose // International Diabetes Federation. - 2007. - Available at: http://www.idf.org.</mixed-citation><mixed-citation xml:lang="en">Guideline for management of postmeal glucose // International Diabetes Federation. - 2007. - Available at: http://www.idf.org.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Алгоритмы специализированной помощи больным сахарным диабетом / Под ред. И.И. Дедова, М.В. Шестаковой. - М., 2009.</mixed-citation><mixed-citation xml:lang="en">Алгоритмы специализированной помощи больным сахарным диабетом / Под ред. И.И. Дедова, М.В. Шестаковой. - М., 2009.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Holman R.R., Paul S.K., Bethel M.A., Mattews D.R., Neil H.A. 10-year follow-up of intensive glucose control in type 2 diabetes mellitus // N. Engl. J. Med. - 2008. - 359. - Р. 1577-1589.</mixed-citation><mixed-citation xml:lang="en">Holman R.R., Paul S.K., Bethel M.A., Mattews D.R., Neil H.A. 10-year follow-up of intensive glucose control in type 2 diabetes mellitus // N. Engl. J. Med. - 2008. - 359. - Р. 1577-1589.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Yki-Jarvinen H. Less nocturnal hypoglycemia and better post-dinner glucose control with bedtime insulin glargine compared with bedtime NPH insulin during insulin combination therapy in type 2 diabetes // Diabetes Care. - 2000. - 23. - Р. 1130-1136.</mixed-citation><mixed-citation xml:lang="en">Yki-Jarvinen H. Less nocturnal hypoglycemia and better post-dinner glucose control with bedtime insulin glargine compared with bedtime NPH insulin during insulin combination therapy in type 2 diabetes // Diabetes Care. - 2000. - 23. - Р. 1130-1136.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Riddle M. The Treat-to-Target Trial: Randomized addition of glargine or human NPH insulin to oral therapy of type 2 diabetic patients // Diabetes Care. - 2003. - 26. - Р. 3080-3086.</mixed-citation><mixed-citation xml:lang="en">Riddle M. The Treat-to-Target Trial: Randomized addition of glargine or human NPH insulin to oral therapy of type 2 diabetic patients // Diabetes Care. - 2003. - 26. - Р. 3080-3086.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Rosenstock J. Reduced hypoglycemia risk with insulin glargine: a metaanalysis comparing insulin glargine with human NPH in type 2 diabetes // Diabetes Care. - 2005. - 28. - Р. 950-955.</mixed-citation><mixed-citation xml:lang="en">Rosenstock J. Reduced hypoglycemia risk with insulin glargine: a metaanalysis comparing insulin glargine with human NPH in type 2 diabetes // Diabetes Care. - 2005. - 28. - Р. 950-955.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Plank J. et al. A double-blind, randomized, dose-response study investigating the pharmacodynamic and pharmacokinetic properties of a longacting insulin analog detemir // Diabetes Care. - 2005. - 28. - Р. 1107-1112.</mixed-citation><mixed-citation xml:lang="en">Plank J. et al. A double-blind, randomized, dose-response study investigating the pharmacodynamic and pharmacokinetic properties of a longacting insulin analog detemir // Diabetes Care. - 2005. - 28. - Р. 1107-1112.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">European Public Assessment Report, LEVEMIR, EMEA 2004, http:www.emea.europa.eu/humandocs/Humans/EPAR/levemir/levemir. htm.</mixed-citation><mixed-citation xml:lang="en">European Public Assessment Report, LEVEMIR, EMEA 2004, http:www.emea.europa.eu/humandocs/Humans/EPAR/levemir/levemir. htm.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Hermansen K., Davies M., Derezinski T. et al. A 26-week, randomized, parallel, treat-to-target trial comparing insulin detemir with NPH insulin as add-on therapy to oral glucose-lowering drugs in insulin-naive people with type 2 diabetes // Diabetes Care. - 2006. - 29. - Р. 1269-1274.</mixed-citation><mixed-citation xml:lang="en">Hermansen K., Davies M., Derezinski T. et al. A 26-week, randomized, parallel, treat-to-target trial comparing insulin detemir with NPH insulin as add-on therapy to oral glucose-lowering drugs in insulin-naive people with type 2 diabetes // Diabetes Care. - 2006. - 29. - Р. 1269-1274.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Philis-Tsimikas A., Charpentier G., Clauson P. et al. Comparison of oncedaily insulin detemir with NPH insulin added to a regimen of oral antidiabetic drugs in poorly controlled type 2 diabetes // Clin. Ther. - 2006. - 28. - Р. 1569-1581.</mixed-citation><mixed-citation xml:lang="en">Philis-Tsimikas A., Charpentier G., Clauson P. et al. Comparison of oncedaily insulin detemir with NPH insulin added to a regimen of oral antidiabetic drugs in poorly controlled type 2 diabetes // Clin. Ther. - 2006. - 28. - Р. 1569-1581.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Rosenstock J., Davies M., Home P.D. et al. A randomized, 52-week, treat-to-target trial comparing insulin detemir with insulin glargine when administered as add-on to glucse-lowering drugs in insulin-naпve people with type 2 diabetes // Diabetologia. - 2008. - 51. - Р. 408-416.</mixed-citation><mixed-citation xml:lang="en">Rosenstock J., Davies M., Home P.D. et al. A randomized, 52-week, treat-to-target trial comparing insulin detemir with insulin glargine when administered as add-on to glucse-lowering drugs in insulin-naпve people with type 2 diabetes // Diabetologia. - 2008. - 51. - Р. 408-416.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
