diaendoСахарный диабетDiabetes mellitus2072-03512072-0378Endocrinology research centre10.14341/2072-0351-5671diaendo-5671Research ArticleСтатьиArticlesВлияние гликозаминогликанов на течение диабетической нефропатии на стадии микроальбуминурии у больных сахарным диабетом 2 типаEffect of glycosoaminoglycans on the clinical course of diabetic nephropathy at the stage of microalbuminuria in patients with type 2 diabetes mellitusСеменоваИя ВладимировнаSemenovaIya Vladimirovnaiya_semenova@mail.ruЧугуноваЛюдмила АлександровнаChugunovaLyudmila AlexandrovnaИльинАлександр ВикторовичIl'inAlexander ViktorovichКнязеваАнна ПетровнаKnyazevaAnna PetrovnaЧирковаЛидия ДмитриевнаChirkovaLidia DmitrievnaШестаковаМарина ВладимировнаShestakovaMarina Vladimirovnanephro@endocrincentr.ruДедовИван ИвановичDedovIvan Ivanovichdedov@endocrincentr.ruФГУ Эндокринологический научный центр, МоскваРоссияEndocrinology Research Centre, MoscowRussian Federation201015062010132№2 (2010)3439Copyright © Семенова И.В., Чугунова Л.А., Ильин А.В., Князева А.П., Чиркова Л.Д., Шестакова М.В., Дедов И.И., 20102010Семенова И.В., Чугунова Л.А., Ильин А.В., Князева А.П., Чиркова Л.Д., Шестакова М.В., Дедов И.И.Semenova I.V., Chugunova L.A., Il'in A.V., Knyazeva A.P., Chirkova L.D., Shestakova M.V., Dedov I.I.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.dia-endojournals.ru/jour/article/view/5671сахарный диабетдиабетическая нефропатиямикроальбуминуриягепарансульфатсулодексидdibetes mellitusdiabetic nephropathymicroalbuminuriaheparin sulfatesulodexideReferencesДедов И.И., Шестакова М.В. Диабетическая нефропатия. - М.: Уни- версум Паблишинг, 2000. - C. 114.Дедов И.И., Шестакова М.В. Диабетическая нефропатия. - М.: Уни- версум Паблишинг, 2000. - C. 114.Yildirimtьrk O., Kilicgedik M., Tuğcu A., Aytekin V., Aytekin S. The relationship of microalbuminuria with left ventricular functions and silent myocardial ischemia in asymptomatic patients with type 2 diabetes // Arch. Turk. Soc. Cardiol. - 2009. - 37(2). - Р. 91-97.Yildirimtьrk O., Kilicgedik M., Tuğcu A., Aytekin V., Aytekin S. The relationship of microalbuminuria with left ventricular functions and silent myocardial ischemia in asymptomatic patients with type 2 diabetes // Arch. Turk. Soc. Cardiol. - 2009. - 37(2). - Р. 91-97.Borch-Johnsen K., Feldt-Rasmussen B., Strandgaard S., Schroll M., Jensen J.S. Urinary albumin excretion. An independent predictor of ischemic heart disease // Arterioscler Thromb. Vasc. Biol. - 1999. - 19. - P. 1992-1997.Borch-Johnsen K., Feldt-Rasmussen B., Strandgaard S., Schroll M., Jensen J.S. Urinary albumin excretion. An independent predictor of ischemic heart disease // Arterioscler Thromb. Vasc. Biol. - 1999. - 19. - P. 1992-1997.Dinneen S.F., Gerstein H.C. The association of microalbuminuria and mortality in non-insulin-dependent diabetes mellitus. A systematic overview of the literature // Arch. Intern. Med. - 1997. - 157. - P. 1413-1418.Dinneen S.F., Gerstein H.C. The association of microalbuminuria and mortality in non-insulin-dependent diabetes mellitus. A systematic overview of the literature // Arch. Intern. Med. - 1997. - 157. - P. 1413-1418.Wei-Wei Zhan, Yu-Hong Chen, Yi-Fei Zhang. Carotid stiffness and microalbuminuria in patients with type 2 diabetes // Endocrine. - 2009. - 35 - P. 409-413.Wei-Wei Zhan, Yu-Hong Chen, Yi-Fei Zhang. Carotid stiffness and microalbuminuria in patients with type 2 diabetes // Endocrine. - 2009. - 35 - P. 409-413.Aekplakorn W., Srivanichakorn S., Sangwatanaroj S. Microalbuminuria and metabolic risk factors in patients with type 2 diabetes in primary care setting in Thailand // Diabetes Res. Clin. Pract. - 2009. - 84(1). - P. 92-98.Aekplakorn W., Srivanichakorn S., Sangwatanaroj S. Microalbuminuria and metabolic risk factors in patients with type 2 diabetes in primary care setting in Thailand // Diabetes Res. Clin. Pract. - 2009. - 84(1). - P. 92-98.Zhou J., Jia W.P., Ma X.J., Bao Y.Q., Lu W., Li M., Li Q., Hu C., Xiang K.S. Relationship between blood glucose variability and microalbuminuria in type 2 diabetic patients with well-controlled glycosylated hemoglobin // Article in Chinese. Zhonghua Yi Xue Za Zhi. - 2008. - 18(42). - P. 2977-2981.Zhou J., Jia W.P., Ma X.J., Bao Y.Q., Lu W., Li M., Li Q., Hu C., Xiang K.S. Relationship between blood glucose variability and microalbuminuria in type 2 diabetic patients with well-controlled glycosylated hemoglobin // Article in Chinese. Zhonghua Yi Xue Za Zhi. - 2008. - 18(42). - P. 2977-2981.Stehouwer C.D., Fischer H.R., van Kuijk A.W., Polak B.C., Donker A.J. Endothelial dysfunction precedes development of microalbuminuria in IDDM // Diabetes. - 1995. - 44. - P. 561-564.Stehouwer C.D., Fischer H.R., van Kuijk A.W., Polak B.C., Donker A.J. Endothelial dysfunction precedes development of microalbuminuria in IDDM // Diabetes. - 1995. - 44. - P. 561-564.Deckert T., Feldt-Rasmussen B., Borch-Johnsen K., Jensen T., Kofoed-Enevoldsen A. Albuminuria reflects widespread vascular damage. The Steno hypothesis // Diabetologia. - 1989. - 32(4). - P. 219-226.Deckert T., Feldt-Rasmussen B., Borch-Johnsen K., Jensen T., Kofoed-Enevoldsen A. Albuminuria reflects widespread vascular damage. The Steno hypothesis // Diabetologia. - 1989. - 32(4). - P. 219-226.Amann K., Wanner C., Ritz E. Cross-talk between the kidney and the cardiovascular system // J. Am. Soc. Nephrol. - 2006. - 17. - P. 2112- 2119.Amann K., Wanner C., Ritz E. Cross-talk between the kidney and the cardiovascular system // J. Am. Soc. Nephrol. - 2006. - 17. - P. 2112- 2119.Satchell S., Anderson K., Mathieson P. Angiopoietin 1 and vascular endothelial growth factor modulate human glomerular endothelial cell barrier properties // J. Am. Soc. Nephrol. - 2004. - 15. - P. 566-574.Satchell S., Anderson K., Mathieson P. Angiopoietin 1 and vascular endothelial growth factor modulate human glomerular endothelial cell barrier properties // J. Am. Soc. Nephrol. - 2004. - 15. - P. 566-574.Jarad G., Miner J. Update on the glomerular filtration barrier // Curr. Opin. Nephrol. Hypertens. - 2009. - 18(3). - P. 226-232.Jarad G., Miner J. Update on the glomerular filtration barrier // Curr. Opin. Nephrol. Hypertens. - 2009. - 18(3). - P. 226-232.Pries A., Secomb T., Gaehtgens P. The endothelial surface layer // Pflugers. Arch. - 2000. - 440. - P. 653-666.Pries A., Secomb T., Gaehtgens P. The endothelial surface layer // Pflugers. Arch. - 2000. - 440. - P. 653-666.Salmon A., Neal C., Harper S. New aspects of glomerular filtration barrier structure and function: five layers (at least) not three // Curr. Opin. Nephrol. Hypertens. - 2009. - 18(3). - P. 197-205.Salmon A., Neal C., Harper S. New aspects of glomerular filtration barrier structure and function: five layers (at least) not three // Curr. Opin. Nephrol. Hypertens. - 2009. - 18(3). - P. 197-205.Satchell S., Tooke J. What is the mechanism of microalbuminuria in diabetes: a role for the glomerular endothelium? // Diabetologia. - 2008. - 51(5). - P. 714-772.Satchell S., Tooke J. What is the mechanism of microalbuminuria in diabetes: a role for the glomerular endothelium? // Diabetologia. - 2008. - 51(5). - P. 714-772.Max Nieuwdorp, Hans L. Mooij, Kroon J. Endothelial Glycocalyx Damage Coincides With Microalbuminuria in Type 1 Diabetes // Diabetes. - 2006. - 55. -P. 1127-1132.Max Nieuwdorp, Hans L. Mooij, Kroon J. Endothelial Glycocalyx Damage Coincides With Microalbuminuria in Type 1 Diabetes // Diabetes. - 2006. - 55. -P. 1127-1132.Gambaro G., Kinalska I., Oksa A., Pont'uch P., Hertlovб M., Olsovsky J., Manitius J., Fedele D., Czekalski S., Perusicovб J., Skrha J., Taton J., Grzeszczak W., Crepaldi G. Oral sulodexide reduces albuminuria in microalbuminuric and macroalbuminuric type 1 and type 2 diabetic patients: The Di.N.A.S. randomized trial // J. Am. Soc. Nephrol. - 2002. - 13. - P. 1615-1625.Gambaro G., Kinalska I., Oksa A., Pont'uch P., Hertlovб M., Olsovsky J., Manitius J., Fedele D., Czekalski S., Perusicovб J., Skrha J., Taton J., Grzeszczak W., Crepaldi G. Oral sulodexide reduces albuminuria in microalbuminuric and macroalbuminuric type 1 and type 2 diabetic patients: The Di.N.A.S. randomized trial // J. Am. Soc. Nephrol. - 2002. - 13. - P. 1615-1625.Singh A., Satchell S.C., Neal C.R., McKenzie E.A., Tooke J.E., Mathieson P.W. Glomerular Endothelial Glycocalyx Constitutes a Barrier to Protein Permeability // J. Am. Soc. Nephrol. - 2007. - 18. - P. 2885-2893.Singh A., Satchell S.C., Neal C.R., McKenzie E.A., Tooke J.E., Mathieson P.W. Glomerular Endothelial Glycocalyx Constitutes a Barrier to Protein Permeability // J. Am. Soc. Nephrol. - 2007. - 18. - P. 2885-2893.Harvey S., Miner J. Revisiting the glomerular charge barrier in the molecular era // Curr. Opin. Nephrol. Hypertens. - 2008. - 17(4). - P. 393-398.Harvey S., Miner J. Revisiting the glomerular charge barrier in the molecular era // Curr. Opin. Nephrol. Hypertens. - 2008. - 17(4). - P. 393-398.Miner J.H. Renal basement membrane components // Kidney. Int. - 1999. - 56. - P. 2016-2024.Miner J.H. Renal basement membrane components // Kidney. Int. - 1999. - 56. - P. 2016-2024.Abaterusso C., Gambaro G. The role of glycosaminoglycans and sulodexide in the treatment of diabetic nephropathy // Treat. Endocrinol. - 2006. - 5(4). - P. 211-222.Abaterusso C., Gambaro G. The role of glycosaminoglycans and sulodexide in the treatment of diabetic nephropathy // Treat. Endocrinol. - 2006. - 5(4). - P. 211-222.
The authors declare that there are no conflicts of interest present.