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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">diaendo</journal-id><journal-title-group><journal-title xml:lang="ru">Сахарный диабет</journal-title><trans-title-group xml:lang="en"><trans-title>Diabetes mellitus</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2072-0351</issn><issn pub-type="epub">2072-0378</issn><publisher><publisher-name>Endocrinology research centre</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14341/2072-0351-5646</article-id><article-id custom-type="elpub" pub-id-type="custom">diaendo-5646</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Articles</subject></subj-group></article-categories><title-group><article-title>Возможно ли безопасное достижение целевого уровня гликированного гемоглобина при интенсивном режиме сахароснижающей терапии (по результатам исследования ADVANCE)</article-title><trans-title-group xml:lang="en"><trans-title>Is it possible to achieve a safe glycated hemoglobin level during intensive hypoglycemic therapy? (results of ADVANCE study)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шестакова</surname><given-names>Марина Владимировна</given-names></name><name name-style="western" xml:lang="en"><surname>Shestakova</surname><given-names>Marina Vladimirovna</given-names></name></name-alternatives><email xlink:type="simple">-</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шамхалова</surname><given-names>Минара Шамхаловна</given-names></name><name name-style="western" xml:lang="en"><surname>Shamkhalova</surname><given-names>Minara Shamkhalovna</given-names></name></name-alternatives><email xlink:type="simple">shamkhalova@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГУ Эндокринологический научный центр, Москва</institution></aff><aff xml:lang="en"><institution>Endocrinological Research Centre, Moscow</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2011</year></pub-date><pub-date pub-type="epub"><day>15</day><month>06</month><year>2011</year></pub-date><volume>14</volume><issue>2</issue><issue-title>№2 (2011)</issue-title><fpage>110</fpage><lpage>115</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Шестакова М.В., Шамхалова М.Ш., 2011</copyright-statement><copyright-year>2011</copyright-year><copyright-holder xml:lang="ru">Шестакова М.В., Шамхалова М.Ш.</copyright-holder><copyright-holder xml:lang="en">Shestakova M.V., Shamkhalova M.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.dia-endojournals.ru/jour/article/view/5646">https://www.dia-endojournals.ru/jour/article/view/5646</self-uri><abstract/><trans-abstract xml:lang="en"/><kwd-group xml:lang="ru"><kwd>сахарный диабет</kwd><kwd>гликлазид с модифицированным высвобождением</kwd><kwd>гликированный гемоглобин</kwd><kwd>интенсивный контроль глюкозы</kwd><kwd>исследование ADVANCE</kwd></kwd-group><kwd-group xml:lang="en"><kwd>diabetes mellitus</kwd><kwd>glyclazide modified release</kwd><kwd>glycated hemoglobin</kwd><kwd>intensive blood glucose control</kwd><kwd>ADVANCE study</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">IDF Diabetes Atlas, 4-H edition, 2009.</mixed-citation><mixed-citation xml:lang="en">IDF Diabetes Atlas, 4-H edition, 2009.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Moss S.E., Klein R., Klein B.E., Meuer S.M. 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