diaendoСахарный диабетDiabetes mellitus2072-03512072-0378Endocrinology research centre10.14341/2072-0351-5546diaendo-5546Research ArticleСтатьиArticlesВоздействие на факторы риска - реальный путь профилактики сосудистых осложнений сахарного диабета 2 типаTargeting risk factors: a feasible way for prevention of vascular complications in type 2 diabetes mellitusКононенкоИрина ВладимировнаKononenkoIrina Vladimirovnashakhtarina@bk.ruСмирноваОльга МихайловнаSmirnovaOlga Mikhailovnadr_smr@mail.ruФГБУ "Эндокринологический научный центр" Минздрава РоссииРоссияEndocrinology Research CentreRussian Federation201215122012154№4 (2012)103108Copyright © Кононенко И.В., Смирнова О.М., 20122012Кононенко И.В., Смирнова О.М.Kononenko I.V., Smirnova O.M.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.dia-endojournals.ru/jour/article/view/5546

Настоящая статья посвящена проблеме профилактики сосудистых осложнений у больных сахарным диабетом 2 типа (СД2) и необходимости мультифакторного подхода в лечении данной категории больных. Представлены результаты самого масштабного в диабетологии исследования ADVANCE (Action in Diabetes and Vascular Disease: Preterax and Diamicron Modified Release Controlled Evaluation) о сочетанном влиянии гипотензивной терапии и ин- тенсивной сахароснижающей терапии на риск развития микро- и макрососудистых осложнений СД2.

The article addresses challenges in the prevention of microvascular complications in type 2 diabetes mellitus (T2DM) and discusses necessity of multifactorial approach to management of these conditions. We present results of a large-scale ADVANCE (Action in Diabetes and Vascular Disease: Preterax and Diamicron Modified Release Controlled Evaluation) trial that elucidates the combined influence of antihypertensive and of intensive glucose-lowering therapy on the risk of development of micro- and macrovascular complications of T2DM

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The authors declare that there are no conflicts of interest present.