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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">diaendo</journal-id><journal-title-group><journal-title xml:lang="ru">Сахарный диабет</journal-title><trans-title-group xml:lang="en"><trans-title>Diabetes mellitus</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2072-0351</issn><issn pub-type="epub">2072-0378</issn><publisher><publisher-name>Endocrinology research centre</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14341/2072-0351-5544</article-id><article-id custom-type="elpub" pub-id-type="custom">diaendo-5544</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Articles</subject></subj-group></article-categories><title-group><article-title>Пошаговая индивидуальная интенсификация инсулинотерапии инсулиновыми аналогами при сахарном диабете 2 типа</article-title><trans-title-group xml:lang="en"><trans-title>Individual stepwise intensification of insulin analogue therapy in type 2 diabetes mellitus</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Аметов</surname><given-names>Александр Сергеевич</given-names></name><name name-style="western" xml:lang="en"><surname>Ametov</surname><given-names>Alexander Sergeevich</given-names></name></name-alternatives><email xlink:type="simple">nachendoc@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Черникова</surname><given-names>Наталья Альбертовна</given-names></name><name name-style="western" xml:lang="en"><surname>Chernikova</surname><given-names>Natalya Al'bertovna</given-names></name></name-alternatives><email xlink:type="simple">nachendoc@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГБОУ ДПО Российская медицинская академия последипломного образования</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Russian medical academy of postdegree education</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2012</year></pub-date><pub-date pub-type="epub"><day>15</day><month>12</month><year>2012</year></pub-date><volume>15</volume><issue>4</issue><issue-title>№4 (2012)</issue-title><fpage>89</fpage><lpage>94</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Аметов А.С., Черникова Н.А., 2012</copyright-statement><copyright-year>2012</copyright-year><copyright-holder xml:lang="ru">Аметов А.С., Черникова Н.А.</copyright-holder><copyright-holder xml:lang="en">Ametov A.S., Chernikova N.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.dia-endojournals.ru/jour/article/view/5544">https://www.dia-endojournals.ru/jour/article/view/5544</self-uri><abstract><p>В данной статье представлены основные этапы и режимы интенсификации инсулинотерапии при сахарном диабете 2 типа (СД2). Интенсификация инсулинотерапии наиболее часто осуществляется путем присоединения к базаль- ному инсулину прандиального инсулина в основные приемы пищи с учетом постпрандиальной гликемии. Обновленный консенсус ADA/EASD (апрель 2012 г.) особую роль отводит поэтапной, пошаговой, основанной на индивидуальном целевом уровне гликемии интенсификации инсулинотерапии. Назначая инсулиновые аналоги для интенсификации инсулинотерапии пациентам с СД2, врач значительно упрощает схему обучения и самоконтроля своим пациентам.</p></abstract><trans-abstract xml:lang="en"><p>Article reviews basic steps and regimens of insulin analogue therapy intensification in patients with type 2 diabetes mellitus (T2DM). Intensification of insulin therapy is commonly implemented by supplementation of basal insulin with prandial before breakfast, lunch and dinner. Updated EASD/ADA guidelines (August 2012) recommend individual stepwise intensification of T2DM insulin therapy. Application of insulin analogues simplifies diabetes training and patient self-monitoring.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>сахарный диабет 2 типа</kwd><kwd>интенсификация инсулинотерапии</kwd><kwd>обучение больных сахарным диабе- том</kwd><kwd>самоконтроль</kwd><kwd>инсулиновые аналоги</kwd></kwd-group><kwd-group xml:lang="en"><kwd>type 2 diabetes mellitus</kwd><kwd>insulin therapy intensification</kwd><kwd>diabetes training</kwd><kwd>self-monitoring</kwd><kwd>insulin analogues</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Ametov AS. Type 2 Diabetes Mellitus. Challenges and decisions . Moscow: GEOTAR-Media; 2011. p. 10-11.</mixed-citation><mixed-citation xml:lang="en">Ametov AS. Type 2 Diabetes Mellitus. Challenges and decisions . 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