diaendoСахарный диабетDiabetes mellitus2072-03512072-0378Endocrinology research centre10.14341/2072-0351-5542diaendo-5542Research ArticleСтатьиArticlesНарушения фосфорно-кальциевого обмена у пациентов с сахарным диабетом и хронической болезнью почекCompromised calcium and phosphorus metabolism in patients with diabetes mellitus and chronic kidney diseaseБираговаМаргарита СтаниславовнаBiragovaMargarita Stanislavovnarituzik-uezd@mail.ruГрачеваСветлана АлександровнаGrachevaSvetlana Alexandrovnaorg@endocrincentr.ruМартыновСергей АндреевичMartynovSergey Andreevichorg@endocrincentr.ruФГБУ "Эндокринологический научный центр" Минздрава РоссииРоссияEndocrinology Research CentreRussian Federation201215122012154№4 (2012)7480Copyright © Бирагова М.С., Грачева С.А., Мартынов С.А., 20122012Бирагова М.С., Грачева С.А., Мартынов С.А.Biragova M.S., Gracheva S.A., Martynov S.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.dia-endojournals.ru/jour/article/view/5542

Минеральные и костные нарушения (МКН) являются одним из проявлений хронической болезни почек (ХБП). Значимость МКН не ограничивается нарушениями только костного метаболизма. В настоящее время широко обсуждаются его внекостные проявления, такие как сосудистая кальцификация, анемия, артериальная гипертензия, увеличивающие смертность больных с ХБП. В связи с этим, ведется активный поиск и разработка новых подходов к коррекции МКН. Современные препараты способны не только нормализовать показатели фосфорно-кальциевого обмена, уровень паратиреоидного гормона, уменьшить морфологические изменения костной ткани, но и обладают кардио- и нефропротективными свойствами, что делает их препаратами выбора в лечении МКН при ХБП.

Disturbance of bone and mineral metabolism (BMM) is one of manifestations of chronic kidney disease (CKD), but its significance goes beyond bone disorders per se. Current discourse is as broad as to include vascular calcification, anemia and arterial hypertension, - conditions increasing mortality in patients with CKD. In this regard the active search for and development of novel approach to correction of BMM is under way. Apart from capacity to normalize calcium and phosphorus metabolism, parathyroid hormone secretion and to reduce morphologic alterations of bone tissue, modern therapeutic agents feature cardio- and renoprotective capabilities, which make them a treatment of choice for compromised BMM in CKD.

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The authors declare that there are no conflicts of interest present.