diaendoСахарный диабетDiabetes mellitus2072-03512072-0378Endocrinology research centre10.14341/2072-0351-5522diaendo-5522Research ArticleСтатьиArticlesСтатины и сахарный диабет: цена сотрудничестваStatins and diabetes mellitus: price of collaborationАлександровАндрей АлексеевичAleksandrovAndrey Alexeevichendocar@mail.ruЯдрихинскаяМария НиколаевнаYadrikhinskayaMaria Nikolaevna-КухаренкоСветлана СеменовнаKukharenkoSvetlana Semenovna-ШацкаяОльга АлександровнаShatskayaOlga Alexandrovna-ФГБУ Эндокринологический научный центр, МоскваEndocrinology Research Centre, Moscow201215062012152№2 (2012)7076Copyright © Александров А.А., Ядрихинская М.Н., Кухаренко С.С., Шацкая О.А., 20122012Александров А.А., Ядрихинская М.Н., Кухаренко С.С., Шацкая О.А.Aleksandrov A.A., Yadrikhinskaya M.N., Kukharenko S.S., Shatskaya O.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.dia-endojournals.ru/jour/article/view/5522

Клиническое использование статинов для первичной и вторичной профилактики сердечно-сосудистых осложнений у боль-ных сахарным диабетом достоверно улучшает продолжительность жизни этих больных. Мета-анализ основных рандоми-зированных исследований свидетельствует о том, что при применении статинов отмечается повышение уровня глюкозыв крови и увеличение количества больных с симптомами сахарного диабета. Особенно это выражено у больных с высокимриском развития нарушений углеводного обмена. Сопоставление положительных и нежелательных свойств статинов,однако, свидетельствует о клинической пользе назначения данной группы препаратов.

It is now well established that clinical use of statins for primary and secondary prevention of cardiovascular complications in patientswith diabetes mellitus (DM) increases life expectancy. At the same time, meta-analysis of major randomized trials shows statins to increaseglycemic levels and incidence of diabetic symptoms, especially in patients at risk for developing glycemic disorders. However,comparison of positive and negative effects of statins suggests prevalence of clinically beneficial factors.

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The authors declare that there are no conflicts of interest present.